Head Injury

[David PS]

This appeared in my new feed.

Possible anti-inflammatory, antioxidant, and neuroprotective effects of apigenin in the setting of mild traumatic brain injury: an investigation - PubMed

The results of this study revealed that apigenin 20 and 40 mg treatment may have neuroprotective effects in mild TBI via decreasing the level of luminol and lucigenin and increasing the IL-10 levels. Additionally, apigenin 20 mg treatment ameliorated the trauma-induced cortical tissue damage.

pubmed.ncbi.nlm.nih.gov

 

[Peatness]

This appeared in my new feed.

Possible anti-inflammatory, antioxidant, and neuroprotective effects of apigenin in the setting of mild traumatic brain injury: an investigation - PubMed

The results of this study revealed that apigenin 20 and 40 mg treatment may have neuroprotective effects in mild TBI via decreasing the level of luminol and lucigenin and increasing the IL-10 levels. Additionally, apigenin 20 mg treatment ameliorated the trauma-induced cortical tissue damage.

pubmed.ncbi.nlm.nih.gov

Thank you

 

[Peatness]

Iodine Redistribution During Trauma, Sepsis, and... : Critical Care Explorations

arctic ground squirrels. Preclinical interventional study using hind-limb ischemia and reperfusion injury in mice. Setting: Level I trauma center emergency room and ICU and animal research laboratories. Subjects: Adult human sepsis and trauma patients, wild-caught adult arctic ground...

journals.lww.com

Conclusion: Iodide redistributes during stress and improves outcome after injury. Essential functions of iodide may have contributed to its evolutionary selection and be useful as a therapeutic intervention for human patients.

 

[Peatness]

Thyroid test abnormalities in traumatic brain injury: correlation with neurologic impairment and sympathetic nervous system activation

Thyroid test abnormalities in traumatic brain injury: correlation with neurologic impairment and sympathetic nervous system activation - PubMed

Acute illness is well known to affect thyroid function, but there are few studies correlating the severity of the underlying medical problem with indexes of thyroid function and little is known about its cause. Traumatically brain-injured patients were selected because they were a relatively...

pubmed.ncbi.nlm.nih.gov

 

[Peatness]

Does anyone have experience with healing scalp injury? The issue is scalp tension (scarring). The hair growth is normal but the scalp is tender and hard.

 

[Peatness]

Traumatic brain injury alters the gut-derived serotonergic system and associated peripheral organs - PubMed

Most efforts to understand the pathology of traumatic brain injury (TBI) have been centered on the brain, ignoring the role played by systemic physiology. Gut-derived serotonin is emerging as a major regulator of systemic homeostasis involving various organs and tissues throughout the body...

pubmed.ncbi.nlm.nih.gov

 

[Peatness]

Effectiveness of bed rest after mild traumatic brain injury: a randomised trial of no versus six days of bed rest - PubMed

As a means of speeding up recovery of patients with PTC after MTBI, bed rest is no more effective than no bed rest at all. Bed rest probably has some palliative effect within the first two weeks after the trauma.

pubmed.ncbi.nlm.nih.gov

Conclusions: As a means of speeding up recovery of patients with PTC after MTBI, bed rest is no more effective than no bed rest at all. Bed rest probably has some palliative effect within the first two weeks after the trauma.

 

[Peatness]

Traumatic brain injury results in mast cell increase and changes in regulation of central histamine receptors - PubMed

Experimental fluid-percussion models produce brain injury by rapidly injecting saline into the closed cranium of rats. In this study our purpose was to determine how the central histaminergic system, which controls excitability and neurotransmitter release through G-protein coupled receptors, is...

pubmed.ncbi.nlm.nih.gov

A PhD thesis, not read. Might have some useful references.

HEAD TRAUMA RELEASE OF HISTAMINE FROM DURAL MAST CELLS ALTERS BLOOD-BRAIN BARRIER: ATTENUATION WITH ZOLANTIDINE

https://digital.library.unt.edu/ark:/67531/metadc2714/m2/1/high_res_d/Dissertation.pdf

 

[Peatness]

3 Micronutrients to Help with Wound Healing

By Lauren Lazarevski, RN, BSN, CWOCN Could metallic micronutrients be the missing link for your patient with a chronic wound? When we consider the nutrition required to optimize wound healing, protein supplementation is usually the star of the show. However, there are micronutrients involved in...

www.woundsource.com

 

[Peatness]

Histamine seems to be slowing done the healing process. If I have to eliminate histamine foods then I will be living on air for a while (not peaty). There's got to be a solution besides cypro which is only going to contribute to an already expanding waistline. I can just about get into my jeans as it stands.

 

[Peatness]

Wow just like that, my prayers answered - all roads lead to thiamine

Regional changes in brain histamine levels following dietary-induced thiamine deficiency in rats

Regional changes in brain histamine levels following dietary-induced thiamine deficiency in rats - PubMed

Histamine levels in thiamine deficient rats were significantly lower in the hippocampus, amygdala, olfactory bulb, thalamus and pons-medulla oblongata than those of normal and pair-fed groups. In the case of the hypothalamus, thiamine deficiency produced a significant increase in histamine...

pubmed.ncbi.nlm.nih.gov

Effects of thiamine administration on hypothermia and hypothalamic histamine levels in dietary-induced thiamine deficient rats - PubMed

The rats maintained on a thiamine-deficient diet for 30 days showed hypothermia, and their histamine levels increased significantly in both the anterior and posterior hypothalamus. When these rats were administered, thiamine disulfide and/or provided with thiamine-added diet for a further 30...

pubmed.ncbi.nlm.nih.gov

 

[Peatness]

View: https://youtu.be/ZgrxfB9zjf0

 

[Peatness]

Myelin and traumatic brain injury: The copper deficiency hypothesis

Nearly two million people suffer traumatic brain injury in the US each year. These injuries alter adversely the metabolism of myelin, a major lipid ma…

www.sciencedirect.com

Serum ceruloplasmin and copper are early biomarkers for traumatic brain injury-associated elevated intracranial pressure - PubMed

High intracranial pressure (ICP) is a prominent secondary pathology after traumatic brain injury (TBI) and is a major contributor to morbidity and mortality. Currently, there are no clinically proven methods for predicting which TBI patients will develop high ICP. In the present study, we...

pubmed.ncbi.nlm.nih.gov

Acquired Copper Deficiency: A Potentially Serious and Preventable Complication Following Gastric Bypass Surgery

Copper is an essential cofactor in many enzymatic reactions vital to the normal function of the hematologic, vascular, skeletal, antioxidant, and neurologic systems. Copper deficiency in the United States is believed to be relatively rare but has been ...

www.ncbi.nlm.nih.gov

Using Copper to Improve the Well-Being of the Skin

Copper has two key properties that are being exploited in consumer and medical device products in the last decade. On the one hand, copper has potent biocidal properties. On the other hand, copper is involved in numerous physiological and metabolic processes critical ...

www.ncbi.nlm.nih.gov

 

[Peatness]

@aliml posted this elsewhere

Dizzy - Nemechek Autonomic Medicine

Learn more about Autonomic Recovery and your health. Read Dizzy

www.nemechekconsultativemedicine.com

 

[Peatness]

Methods to Repair and Regenerate Myelin

Edited By NODE SMITH, ND From Max-Planck-Gesellschaft- The degradation and regeneration of myelin sheaths characterize neurological disorders such as multiple sclerosis. Cholesterol is an indispensable component of myelin sheaths. The […]

ndnr.com

Demyelinating Conditions Like MS Can Be Treated By Androgens

Ray wrote quite a bit on the topic of estrogen as a causative factor in demyelination and progesterone / pregnenolone as remyelinating agents. I posted an animal study recently on using DHT to completely reverse the pathology of the MS that model...

raypeatforum.com

 

[Meecho]

How's your head doing? My head trauma was on July 9. CO2 hat was the most helpful thing for me, by far. You can check the story on my Twitter account @meechomee

 

[Peatness]

How's your head doing? My head trauma was on July 9. CO2 hat was the most helpful thing for me, by far. You can check the story on my Twitter account @meechomee

Wow some great stuff there. Makes me emotional reading it. To be honest I don't know how I survived my injury - I think if I wasn't peating I would have died. My biggest problem is my spine got twisted in the fall exacerbating existing muscular skeletal problems. I have a history of radiation damage so I didn’t have the CT scan I was offered on the day of the fall – I’ve since had an MRI and it looked normal but there were two small clots. Strangely, I felt worse after the MRI (I’ve heard that heavy metals can be redistributed during an MRI – I was given contrast dye some years ago so I have plenty of tissue heavy metals). As it stands I‘ve been trying to figure it all out by myself because whenever I go to a “professional” I am injured in some way. I am going to read more of your tweeter posts – thank you for sharing it.

P.S Please feel free to post anything you think might be helpful on this thread.

 

[Peatness]

@Meecho have you been using high dose thiamine?

 

[BRMarshall]

More about the use of CO2 would be appreciated!

 

[Meecho]

I should probably create a new thread about that.