Restoring Metabolism Prevents / Reverses "permanent" Nerve Damage

[tankasnowgod]

If thyroid can reverse nerve damage, then why do injured tissues reduce T4's conversion to T3 and increase its conversion to reverse-T3?

Because injured tissues aren't the liver?

Also, the term "injured" itself implies that normal function has been impaired.

 

[tankasnowgod]

Healing Midbrain Damage (chronic Fatigue Syndrome)

I've seen this a lot recently, and I keep on thinking of this Krieger quote-

 

[orewashin]

Recoen is following her instincts. "Zinc is also an essential part of the enzyme deiodinase, which converts T4 into functional T3."
Orewashin stop taking T4, your body does not need it. Humble yourself it's far more complex than adding in x and saying I have brain fog right after.... Again what I've been saying this whole time, and I don't even think your understand Peat because you're not getting the relationship of minerals in enzyme cofactors to facilitate natural production and conversion. All this talk about brain fog, post exercise fatigue, chronic fatigue syndrome, neurocognitive testing

Have you tried incorporating more Zinc? Eating Muscle Meat? You understand why so many people are regaining their lives on The Vertical Diet??? Zinc from Beef Muscle Meat!!!!!

My T3 was high-normal on a blood test, there's no reason to convert T4 into T3 if supplemental T3 suffices.

T4 was below-normal and TSH was still high (9). My endo added a small amount of NDT, equivalent to 10 mcg of T4 and 2 mcg of T3, and it was enough for me to develop brain fog. Furthermore, T4 only went up a little bit, T3 went down to low-normal, and TSH skyrocketed to 27.

I've been eating muscle meat daily and nothing is any different. Before this, I'd eat shellfish of different varieties about once a week, much like other Peaters on this forum.

T4 is used for about 10% of metabolic processes and my endo disagrees with T3-only for this reason. While my case, or CFS cases in general, are different, and may benefit from T3-only, in most cases people need T4, or else it becomes a limiting factor in metabolism.

 

[Ledo]

My T3 was high-normal on a blood test, there's no reason to convert T4 into T3 if supplemental T3 suffices.

T4 was below-normal and TSH was still high (9). My endo added a small amount of NDT, equivalent to 10 mcg of T4 and 2 mcg of T3, and it was enough for me to develop brain fog. Furthermore, T4 only went up a little bit, T3 went down to low-normal, and TSH skyrocketed to 27.

I've been eating muscle meat daily and nothing is any different. Before this, I'd eat shellfish of different varieties about once a week, much like other Peaters on this forum.

T4 is used for about 10% of metabolic processes and my endo disagrees with T3-only for this reason. While my case, or CFS cases in general, are different, and may benefit from T3-only, in most cases people need T4, or else it becomes a limiting factor in metabolism.

Hi, You mentioned virus, pre-covid included, as a potential cause but have you ruled that out in your case?

 

[orewashin]

Hi, You mentioned virus, pre-covid included, as a potential cause but have you ruled that out in your case?

I have not. I suffered from a mild viral infection with sore throat and occasional coughing, I think during May or April, but I recovered from it quickly.

My symptoms started over a decade ago during adolescence. I’d be unable to maintain an exercise routine because I’d get tired. Then I caught a virus that was bad enough to prevent me from raising my hand, and I felt weak for months afterward. I already had a good idea of RP’s view and decided to get my thyroid tested.

From that point, I went on and off thyroid because I felt brain fog from T4, but I didn’t isolate it as an issue until recently. My brain fog was minimal on T3-only, but fatigue was still present, which made me suspect CFS.

 

[LeeLemonoil]

I think Asmorbids acids tissue restoring properties partly also stem from its pro metabolic effects ... it has been shown to modify electron transport too

 

[orewashin]

I think Asmorbids acids tissue restoring properties partly also stem from its pro metabolic effects ... it has been shown to modify electron transport too

*ascorbic

I don’t know what asmorbid acid is, but it sounds deadly.

 

[LeeLemonoil]

thanks for correcting that

 

[shine]

Did you do anything in particular to fix your mitochondria when you were ill? I am familiar with vitamin K2, selenium, CO2, b vitamins, COQ10, methylene blue, T3 etc. but just curious if there was anything else

PQQ is pretty good.

 

['peataphysique]

You've seen a neurologist but you have neuropathy in your feet? Assuming you are at an appropriate bmi.. And you have yet to have an MRI of your spine to look for MS lesions, or spinal stenosis? Which very much are significantly connected to autonomic dysreflexia as I have previously mentioned in spinal cord injuries or degrading disc disease, that can effect muscle tone, blood pressure etc.

You've seen an endocrinologist and all your blood labs must have been fine and you're taking t4 and t3 aimlessly and feel better not taking thyroid hormone? You understand that by chasing such a vague syndrome, you are literally not getting anywhere. Emg = nerve conductance, Table tilt test, lol omg how much money are you going to waste? & neurocognitive testing??? You seem like you'll be able to pass:

:Neurocognitive testing is a way to measure brain function non invasively. It uses paper-and-pencil tests or computerized tests to assess important aspects of cognition: attention, memory, language, reaction time, perception, and so on.

Keep barking up the thyroid tree, when your labs are fine.... You know that B vitamins assist in methylation, and various enzymatic processes right? Which you are directly saying some people get healed from CFS from b1 and b2. b2 - Riboflavin being extremely important for MTHFR variant carriers.

I'd get into into counseling, they do more than just help people with emotional problems. They are familiar with the ins and outs of healthcare and can direct you to the help you need. Seriously I'd get a spinal MRI, a gene test so you can now definitely if you are a MTHFR carrier and can supplement riboflavin and folate. But ultimately this shouldn't even be a problem if you are eating several ounces of liver a week...

VI. Diagnosis

In the absence of commercial techniques that reflect thyroid physiology realistically, there is no valid alternative to diagnosis based on the known physiological indicators of hypothyroidism and hyperthyroidism. The failure to treat sick people because of one or another blood test that indicates "normal thyroid function," or the destruction of patients' healthy thyroid glands because one of the tests indicates hyperthyroidism, isn't acceptable just because it's the professional standard, and is enforced by benighted state licensing boards.

Toward the end of the twentieth century, there has been considerable discussion of "evidence-based medicine." Good judgment requires good information, but there are forces that would over-rule individual judgment as to whether published information is applicable to certain patients. In an atmosphere that sanctions prescribing estrogen or insulin without evidence of an estrogen deficiency or insulin deficiency, but that penalizes practitioners who prescribe thyroid to correct symptoms, the published "evidence" is necessarily heavily biased. In this context, "meta-analysis" becomes a tool of authoritarianism, replacing the use of judgment with the improper use of statistical analysis.

Unless someone can demonstrate the scientific invalidity of the methods used to diagnose hypothyroidism up to 1945, then they constitute the best present evidence for evaluating hypothyroidism, because all of the blood tests that have been used since 1950 have been.shown to be, at best, very crude and conceptually inappropriate methods.

Thomas H. McGavack's 1951 book, The Thyroid, was representative of the earlier approach to the study of thyroid physiology. Familiarity with the different effects of abnormal thyroid function under different conditions, at different ages, and the effects of gender, were standard parts of medical education that had disappeared by the end of the century. Arthritis, irregularities of growth, wasting, obesity, a variety of abnormalities of the hair and skin, carotenemia, amenorrhea, tendency to miscarry, infertility in males and females, insomnia or somnolence, emphysema, various heart diseases, psychosis, dementia, poor memory, anxiety, cold extremities, anemia, and many other problems were known reasons to suspect hypothyroidism. If the physician didn't have a device for measuring oxygen consumption, estimated calorie intake could provide supporting evidence. The Achilles' tendon reflex was another simple objective measurement with a very strong correlation to the basal metabolic rate. Skin electrical resistance, or whole body impedance wasn't widely accepted, though it had considerable scientific validity.

A therapeutic trial was the final test of the validity of the diagnosis: If the patient's symptoms disappeared as his temperature and pulse rate and food intake were normalized, the diagnostic hypothesis was confirmed. It was common to begin therapy with one or two grains of thyroid, and to adjust the dose according to the patient's response. Whatever objective indicator was used, whether it was basal metabolic rate, or serum cholesterol. or core temperature, or reflex relaxation rate, a simple chart would graphically indicate the rate of recovery toward normal health.

Thyroid: Therapies, Confusion, and Fraud

 

[paymanz]

@haidut what do you think about creatine increase water content of body, where those extra water stored?

wouldn't that be an unfavored effect If that be intracellular water?!

 

[Texon]

*ascorbic

I don’t know what asmorbid acid is, but it sounds deadly.

Have you ruled out any kind of ongoing mold exposure or food sensitivities? If food related niacinamide can apparently help. Maybe trimethylglycine for liver support could help with mold? Or outright avoidance. Then thiamine comes to mind for autonomic issues. Dr. Derrick Lonsdale at www.hormonesmatter.com is THE expert for that.

 

[Vinny]

Isn't the daily HED more like 20-30g instead of 10-15g because they gave the dose twice daily?

good question

 

[Texon]

CFS is diagnosed when all other potential causes of fatigue are ruled out.

CFS often develops as a result of viral infections.

CFS is linked to differences in deep brain areas on MRI. Areas that are linked to autonomic regulation.

CFS has been researched for years and a treatment has not been found.

With all due respect have you tried one or more of the fat soluble thiamines taken along with a good magnesium supplement?

 

[Regina]

creatine, inosine, progesterone, pregnenolone, niacinamide, thyroid, magnesium, etc.
And I would add aspirin, K2 and minocycline to your mighty list.

I was talking to a man last night whose son (now 26 yr old) had a major spinal injury 2 yrs ago. His son is paralyzed and requires he and his wife's constant attention. The father looked utterly wracked with grief.

I'd have to tread carefully. They are taking him back out to some specialist in Colorado (who hasn't improved the son one iota) and they definitely come as "The Doctor says..." types. Phew.