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Folates Are Serotonin Reuptake Promoters

Discussion in 'Ask For Help or Advice' started by Joeyd, Apr 16, 2018.

  1. Joeyd

    Joeyd Member

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    For people who don't know, Dr. William Walsh wrote Nutrient Power, he's a scientist paving the way for nutrition-based psychiatry and nutritional medicine. He's studied 30,000 patients with mental disorders, and created a database of more than three million chemical assays during his clinical and research work.

    His work focuses on methylation but he's actually more peaty than you would expect, he advises against using SSRI's in most cases and explains that serotonin is largely not relevant when dealing with depression. He also thinks SSRIs are to blame for a lot of the mass school shootings in the US.

    Anyway, here's a excerpt from a podcast where he explains how folates are actually serotonin promoters (reducing serotonin further!)
    https://myersdetox.com/transcript-129-nutrition-and-the-mind-with-dr-william-walsh/

    "
    William Walsh: I have to say that’s not true of most undermethylators. It’s only true of undermethylators who have a brain chemistry problem. And that’s a very small percentage. Eighty or ninety percent of undermethylated people thrive on folic acid. They thrive on vegetables. They do. But ifthey have a tendency for low serotonin activity, they need to be careful.

    Wendy Myers: So then I need to be careful about eating the green leafy vegetables.

    William Walsh: Yeah, because they’re loaded with folate and folate has this powerful effect epigentically that affects reuptake, affects serotonin and dopamine reuptake.

    Wendy Myers: Yeah.

    William Walsh: Folic acid and all folates are wonderful serotonin reuptake promoters. They really enhance reuptake.
    "
     
  2. Peata

    Peata Member

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    I'll have to look into this. I've been taking 400 mcg. folate for a year now.
     
  3. SOMO

    SOMO Member

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    Folic Acid =/= Folate

    I stopped taking a generic One-a-Day-Men's Multivitamin, because of the Folic Acid (it had Folic Acid instead of Folate.) Haven't noticed much of a difference either way, but supposedly Folic Acid can get "stuck" in the body.

    Supplementing with folic acid or folate may interfere with methylation, but I'm fairly certain a healthy diet otherwise would make it so folic acid supplementation would be a net gain.
     
  4. lvysaur

    lvysaur Member

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    do you know your MTHFR status?
     
  5. High_Prob

    High_Prob Member

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    This is a cool find @Joeyd : If what Walsh is saying is true then Folates are acting like a Serotonin Reuptake Enhancer/Promoter (Tianeptine) and depleting Serotonin by increasing its reuptake (instead of inhibiting the reuptake like an SSRI)...Very cool
     
  6. OP
    Joeyd

    Joeyd Member

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    Exactly! I thought it was great news for us peaters
     
  7. Dobbler

    Dobbler Member

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    If you guys try experimenting with folate then go with methylfolate. Its the final and most active form of folate that doenst require any converting further like folate/folic acid.
     
  8. OP
    Joeyd

    Joeyd Member

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    yeah ive been taking it for years. i wouldnt touch folic acid
     
  9. managing

    managing Member

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    So . . . it increases dopamine reuptake also? We don't want this do we?
     
  10. OP
    Joeyd

    Joeyd Member

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    Depends. You could take some Dopamine raising supplements alongside Folate, to lower Serotonin and raise Dopamine overall
     
  11. griesburner

    griesburner Member

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    if you have many of the overmethylation symptoms, is methylfolate then ok? or is folic acid better in this regard, cause it doenst deliever any additional methyl groups? cause i would like to experiment with a folate supplement but i am not sure which to choose.
     
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