Exemestane Vs Letrozole

[dookie]

I've been reading around on these two aromatase inhibitors. It seems letrozole is the most powerful, with longer lasting effects, but exemestane seems "safer", with less side-effects.

Anyone who has tried them and can give a quick comparison?

 

[DennisX]

One of the small side effects I read with exemestane is hair loss in some users. An Arimidex a small side effect is hair thinning in some users. Haven't checked out Letrozole.

 

[redlight]

I take trt and arimidex and am losing hair, maybe its not trt and the arimidex

 

[ddjd]

ive heard exemestane is better because its a suicidal AI

 

[Lyall]

One of the small side effects I read with exemestane is hair loss in some users. An Arimidex a small side effect is hair thinning in some users. Haven't checked out Letrozole.

Would anyone be able to speculate as to the mechanism of hair Loss?

 

[benaoao]

I've read ONCE a progesterone receptor shutdown. So that'd be quite bad for hair health.

I think that taking AIs is a bid idea. Improving glucose metabolism and liver glucuronidation are much more important ie. eating a strict low fat diet

 

[Lyall]

@benaoao thank you for your insights.