Norwegian 2-Day ME/CFS Exercise Study Adds Crucial Factor to Exercise Intolerance Findings - Health Rising
It's easy to think CFS is just a low thyroid, insufficient nutrients, endotoxin problem, etc. But why would it have this unique thing about it, unlike any other condition, unlike the healthy or the sick?? Two day exercise tests (unlike one day tests) reveal anomaly. But why is this happening?
"The remarkable thing is that virtually everyone, whether they’re healthy or sick with any manner of serious diseases, are able to get on a bike, pedal to exhaustion and then pump out the same amount of energy the next day. Whether we’re sick or healthy, somehow our bodies almost always retain the ability to produce energy when needed.
But not apparently in one disease. Chronic fatigue syndrome (ME/CFS) appears to be the odd man out. Put some people with ME/CFS on a bike, and their ability to generate energy (e.g. exercise) the next day plummets. That’s an important finding in a disease which introduced the term post-exertional malaise (PEM) to the medical lexicon.
If that finding holds up – and it’s held up in a number of small studies – it would suggest that exercise does things to people with ME/CFS that it doesn’t appear to do to people with other serious diseases.
When we exercise, our bodies use two different systems – anaerobic and aerobic – to produce energy.The aerobic energy production system dominates during exercise to provide a clean and abundant source of energy. When we reach the limits of our aerobic energy production capacity, the anaerobic energy production begins to dominate – but at a cost. Not only does it produce much less energy, but it also produces toxic by-products which, as they build up, produce pain and fatigue.
The VO2 max CPET exercise test has played an important role in ME/CFS because it measures the transition from aerobic to anaerobic energy. Past two-day exercise studies have suggested that many people with ME/CFS exhaust their aerobic energy production systems more quickly than usual. That leaves them dependent on less efficient anaerobic energy production – and suffering from symptoms of pain and fatigue that quickly kick in when that system predominates."
It's easy to think CFS is just a low thyroid, insufficient nutrients, endotoxin problem, etc. But why would it have this unique thing about it, unlike any other condition, unlike the healthy or the sick?? Two day exercise tests (unlike one day tests) reveal anomaly. But why is this happening?
"The remarkable thing is that virtually everyone, whether they’re healthy or sick with any manner of serious diseases, are able to get on a bike, pedal to exhaustion and then pump out the same amount of energy the next day. Whether we’re sick or healthy, somehow our bodies almost always retain the ability to produce energy when needed.
But not apparently in one disease. Chronic fatigue syndrome (ME/CFS) appears to be the odd man out. Put some people with ME/CFS on a bike, and their ability to generate energy (e.g. exercise) the next day plummets. That’s an important finding in a disease which introduced the term post-exertional malaise (PEM) to the medical lexicon.
If that finding holds up – and it’s held up in a number of small studies – it would suggest that exercise does things to people with ME/CFS that it doesn’t appear to do to people with other serious diseases.
When we exercise, our bodies use two different systems – anaerobic and aerobic – to produce energy.The aerobic energy production system dominates during exercise to provide a clean and abundant source of energy. When we reach the limits of our aerobic energy production capacity, the anaerobic energy production begins to dominate – but at a cost. Not only does it produce much less energy, but it also produces toxic by-products which, as they build up, produce pain and fatigue.
The VO2 max CPET exercise test has played an important role in ME/CFS because it measures the transition from aerobic to anaerobic energy. Past two-day exercise studies have suggested that many people with ME/CFS exhaust their aerobic energy production systems more quickly than usual. That leaves them dependent on less efficient anaerobic energy production – and suffering from symptoms of pain and fatigue that quickly kick in when that system predominates."
