- May 4, 2019
You have lost more muscle?
Yeah It's one of the most scary things about this disease, don't want to think about how much bone and muscle mass I've lost from being sedentary. I try to eat lots of animal protein to sustain myself. Pregnenolone seems to help a bit with anabolism. Might look into something more potent to hold onto lean mass.
I've ordered some TUDCA and will be receiving it shortly. What can you tell me about your experience with TUDCA? What is your reason for taking it?
When I took TUDCA before I noticed immediate improvements with digestion and bile flow (which seem to be permanent). I think low-fat veganism messed up my gallbladder, and TUDCA "unmessed" it.
I have some left and I might as well take it considering the massive amount of research on TUDCA and bile, liver and gut health:
Lowers liver enzymes (Effect of tauroursodeoxycholic acid on serum liver enzymes and dyspeptic symptoms in patients with chronic active hepatitis) reduces gut inflammation, improves barrier function and gut microbiome (Tauroursodeoxycholic acid inhibits intestinal inflammation and barrier disruption in mice with non-alcoholic fatty liver disease - PubMed), increases T4 to T3 conversion, lowers endoplasmatic reticulum stress, anti-inflammatory effects in the brain by reducing glia cell activation, etc ,etc.
Can definitely feel the thyroid boosting effect and perhaps some of the reduced microglia activation, not quite as depressed as usual.