Chemotherapy Causes Cancer Metastases, Tumor Evolution

haidut

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Most people on the forum are familiar with Ray's opinion on "treating" cancer by the "cut, poison, burn" method - i.e. not only it does not work but in many cases makes the cancer more resilient and spread when it otherwise it would not have done so. Well, it seems there is now validation of this idea. This very recent study backed up the two main points - i.e. chemotherapy caused the cancer to evolve (through genetic mutations) and also caused metastases to form. In the group of patients that were not given chemotherapy, none had metastases during the 5-year follow up. However, given that this is coming from Russia and the virtually unknown "Siberian Journal of Oncology" don't expect this to become breaking news in the Western world any time soon.

http://www.eurekalert.org/pub_releases/ ... 113015.php

"...Before the operation, the women received 2-4 courses of neoadjuvant chemotherapy (NAC). Repeated analyzes were taken after surgery to see the therapy effect on the tumor. TSU scientists have found that chemotherapy fully or partially destroyed the tumor clones in the majority of patients, but 23% of women surveyed showed new tumor formation under the influence of NHT. Some chromosomes or parts of them doubled in these clones, and the tumor cells became more resistant. This phenomenon is called amplification, and is a negative consequence of chemotherapy - almost all of these patients experienced development of metastases, while the remaining patients had not metastases in the five-year period of observation. The researchers concluded that under the influence of chemotherapy it is possible to stimulate the evolution of a resistant tumor - one that does not respond to the effects of chemotherapy. "We have preliminary results indicating that chemotherapy may cause the appearance of mutations which had not been observed before in the form of amplifications of chromosomal regions. In some cases it was a reason for occurrence of hematogenous metastasis" - says Marina Ibragimova. We should find out the causes and methods for anticipating tumor development. Thus there is no doubt that chemotherapy shall have strictly personalized character, depending on the properties of tumor and patient. Most of chemotherapy drugs are inherently mutagens; chemotherapy may cause genetic disorders in tumor cells. These genetic disorders may lead to illumination of tumor cells or to their changes. Thus we can observe occurrence of "clones" of the tumor cells, which are able to cope with the chemotherapy. Nowadays the researchers attempt to discover in which cases and how the tumor may develop under effect of chemotherapy."
 
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messtafarian

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There is no one who has had cancer or who knows someone who has cancer who has not been completely convinced this is true. Convinced before, after and during treatment. They have the suspicion they're being killed in some weird experiment to see if they survive. They dream about it. They're truly ill and they shake their heads. They know it is somehow - somehow - wrong.
 

mujuro

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Even in my wider circle of friends, most of whom are not medically inclined, there is developing belief that normal medical intervention in the case of cancer is a waste of time. I think it's a representation of the younger opinion at large, because they have all seen relatives be treated, their bodies deteriorate and watch them die in a sterile hospital bed.

My mother asked me what I would do and I said "5 grams aspirin daily, 500mg caffeine daily. That's probably it".
 

haidut

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mujuro said:
post 112267 Even in my wider circle of friends, most of whom are not medically inclined, there is developing belief that normal medical intervention in the case of cancer is a waste of time. I think it's a representation of the younger opinion at large, because they have all seen relatives be treated, their bodies deteriorate and watch them die in a sterile hospital bed.

My mother asked me what I would do and I said "5 grams aspirin daily, 500mg caffeine daily. That's probably it".

Not a bad approach:): You may want to up the caffeine to 1,500mg daily as a human study showed that patients with colon cancer ALL survived if they ingested that much caffeine daily. And I would add 15mg+ vitamin K2, 100mg doxycycline/minocycline, and 4mg - 8mg cyproheptadine.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923369/
"...These co-administered drugs are so diverse that clearly no common molecular denominator for their combinations is currently in sight. For example, preclinical studies in the rat inoculated with osteosarcoma exposed a striking enhancement by caffeine of the cytocidal effects of platinum-based anticancer drug cisplatin. The extent of tumor inhibition was closely correlated with the average plasma concentration of caffeine [127]. Likewise, adding caffeine to standard chemotherapy enhanced the antitumor response rates in patients with osteosarcoma. On the median follow-up period of 72 months, it extended event-free survival in all patients to 76%, whereas an overall survival reached 100% [128]. Caffeine has also been reported to modulate directly or indirectly the effect of antitumor agents, so as to greatly sensitize tumor cells to genotoxic stress and thus aid in cancer chemoprevention [86]. Chronic exposure to caffeine prior to the appearance of the palpable mammary tumors significantly reduced both the tumor burden and the metastatic colonization [129].


Human study:
http://www.ncbi.nlm.nih.gov/pubmed/19499290/
"...Hematological toxic events were well tolerated in both groups. Grade 4 leukocyte toxicity events occurred in both groups. In the nonmonitoring group grade 2 or higher toxicities included 5 elevated aspartate aminotransferase/alanine aminotransferase level events and 17 hyponatremia events versus 1 hyponatremia event in the monitoring group. Histological examination of excised tumor samples after preoperative chemotherapy revealed that chemotherapeutic efficacy in the monitoring group was as good as in the nonmonitoring group. The median follow-up period in all patients was 72 months. Event-free survival was 76%, and overall survival was 100%."
 
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burtlancast

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Both chemotherapy , radiotherapy AND surgery have long been known to enhance tumor spreading in the long term.

Eli Jones (1850-1933) recognized surgery was detrimental to the cancer patient, and used cancer herbal salves to achieve outstanding cure rates.
In 1911, before retiring, he compiled a book about his methods: Cancer - Its Causes, Symptoms and Treatment (free to download at archive.org: https://archive.org/details/canceritscauses00jonegoog)
https://en.wikipedia.org/wiki/Eli_Jones

Today, cancer specialists scare the bejesus out of you and don't give you any reflection time. 85% of people cannot manage their own health and would never distrust a doctor.

The bigger the lie, the more believable.

There's a lot of deliberate misinformation on the net about alternative cancer therapies, just as there a lot of excellent info.

The problem is having the time to sift through it (while you're dying).
 

jyb

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haidut said:
post 112305
mujuro said:
post 112267 Even in my wider circle of friends, most of whom are not medically inclined, there is developing belief that normal medical intervention in the case of cancer is a waste of time. I think it's a representation of the younger opinion at large, because they have all seen relatives be treated, their bodies deteriorate and watch them die in a sterile hospital bed.

My mother asked me what I would do and I said "5 grams aspirin daily, 500mg caffeine daily. That's probably it".

Not a bad approach:): You may want to up the caffeine to 1,500mg daily as a human study showed that patients with colon cancer ALL survived if they ingested that much caffeine daily. And I would add 15mg+ vitamin K2, 100mg doxycycline/minocycline, and 4mg - 8mg cyproheptadine.

Do you know if/how these patients tolerate 1.5g of caffeine? I am ready to believe that it is possible to build up to that and remain comfortable, as discussed in many threads on this forum, but for the average patient jumping into that?... Unless they are given something else too.
 
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moss

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mujuro said:
post 112267 Even in my wider circle of friends, most of whom are not medically inclined, there is developing belief that normal medical intervention in the case of cancer is a waste of time. I think it's a representation of the younger opinion at large, because they have all seen relatives be treated, their bodies deteriorate and watch them die in a sterile hospital bed.

My mother asked me what I would do and I said "5 grams aspirin daily, 500mg caffeine daily. That's probably it".

True and doctors are dealing with a more educated population and people are now recognizing doctors are not the only source of information. People are starting to question the over prescribing of screening programs. People are asking the questions, do I actually need to have this surgery? do I actually need to take this drug? What lifestyle measures could be tried first and what alternative ways to managing this rather than trust your doctor to 'fix it'.

burtlancast said:
post 114440 Today, cancer specialists scare the bejesus out of you and don't give you any reflection time. 85% of people cannot manage their own health and would never distrust a doctor.

And doctors do not like to be second guessed. The language of cancer prepares one to go into battle with oneself that is intimidating - creating fear and anxiety - people feel pressured into making quick decisions.

What happened to waiting and standing back?

Problem is everyone has an opinion and won't leave you alone long enough to give you time to think/read things through in a coherent and considered way.
 
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Spondive

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I love reading all your posts! I am a medical doctor and been reading Peat and this forum and really enjoy it. I think it is a system problem of corporate control and paternalism..the doctors are not totally to blame..for example I went 15 years of school and have a massive amount of debt..if I don't practice what they call the standard of care I would be labeled a quack or have the potential of losing my liscence..it is a perfect system of control. I think there are a lot of physicians that agree as so do I with you guys but is talked privately and not practiced publicly .

Anyway as I recall to add to what Haidut says I would ramp up thyroid possibly T3 until in a slight hyperthyroid state...I read Peat talking about this to get the heart rate above 100 if one has cancer. Any other thoughts I would always love to hear
 

moss

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Spondive said:
post 114469 I love reading all your posts! I am a medical doctor and been reading Peat and this forum and really enjoy it. I think it is a system problem of corporate control and paternalism..the doctors are not totally to blame..for example I went 15 years of school and have a massive amount of debt..if I don't practice what they call the standard of care I would be labeled a quack or have the potential of losing my liscence..it is a perfect system of control. I think there are a lot of physicians that agree as so do I with you guys but is talked privately and not practiced publicly .

Anyway as I recall to add to what Haidut says I would ramp up thyroid possibly T3 until in a slight hyperthyroid state...I read Peat talking about this to get the heart rate above 100 if one has cancer. Any other thoughts I would always love to hear

Spondive, thanks for the reminder. You are right, of course there are some great independent thinking physicians out there that agree with much that may be expressed here or with Peat writings....doctors do talk privately, not publicly and have their hands tied within the system.
I also think it is good to have the conversations and spread the word and speak out where possible.
 
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Spondive

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I agree Moss..I do bring it up and I get the cartoon six head pop up stare lol.. I wish I had more balls
 

burtlancast

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Spondive said:
post 114469.if I don't practice what they call the standard of care I would be labeled a quack or have the potential of losing my liscence..it is a perfect system of control.

If i may ask, around what time period in your training did you realize you're not free, as doctor, to prescribe what your consider best for your patients ?

This of course goes against everything advertised in the medias, 24/7, about the medical profession.
 
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haidut

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Spondive said:
post 114469 I love reading all your posts! I am a medical doctor and been reading Peat and this forum and really enjoy it. I think it is a system problem of corporate control and paternalism..the doctors are not totally to blame..for example I went 15 years of school and have a massive amount of debt..if I don't practice what they call the standard of care I would be labeled a quack or have the potential of losing my liscence..it is a perfect system of control. I think there are a lot of physicians that agree as so do I with you guys but is talked privately and not practiced publicly .

Anyway as I recall to add to what Haidut says I would ramp up thyroid possibly T3 until in a slight hyperthyroid state...I read Peat talking about this to get the heart rate above 100 if one has cancer. Any other thoughts I would always love to hear

Hi Spondive, thanks for the nice words! Here are some other cancer-specific threads I have posted. I think the tetracyclines and some the related quinones like beta-lapachone and emodin are very promising.
viewtopic.php?f=108&t=6763
viewtopic.php?t=5762
viewtopic.php?f=75&t=3637
viewtopic.php?t=7352
viewtopic.php?f=243&t=5579
viewtopic.php?f=116&t=5814
viewtopic.php?f=85&t=6213
viewtopic.php?t=6410
https://www.raypeatforum.com/forum/viewtopic.php?t=3211
viewtopic.php?t=6833
https://www.raypeatforum.com/forum/viewtopic.php?t=2508

And apparently, without much noise or public admission of guilt, the pharma industry has patented a form of the beta-lapachone quinone (derivative of vitamin K) and is using it for pancreatic cancer. If this works I would like to hear an explanation of its effects that would not contradict the genetics doctrine of cancer somehow. People will be probably too giddy to demand an explanation though...
https://clinicaltrials.gov/ct2/show/NCT02514031
https://clinicaltrials.gov/ct2/show/NCT00102700

Finally, in confirmation of Peat's writings on quinones, emodin from Cascara also seems effective against pancreatic cancer. I am not picking on pancreatic cancer specifically, it just seems that pharma is studying it more intensively than other conditions probably due to its deadliness and how newsworthy any treatment advance would be.
https://www.reddit.com/r/science/commen ... quinone_a/
http://journals.plos.org/plosone/articl ... ne.0042146

The human equivalent dose for emodin is only about 250mg, which is achievable with a few grams of Cascara bark.

And again, thanks for reaching out. It is always nice to hear that someone with official medical background is taking interest in such "fringe" work.
 
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Lilac

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Many years ago, I read a story about musician Melissa Etheridge, who had breast cancer, I believe. She was complaining bitterly about how horrible the treatments had been, and she said they have to find a better way. I remember thinking what a spoiled diva she was. "Modern medicine has kept you alive, and you're complaining." Now, I see, she was right!
 

Suikerbuik

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Thanks for bringing this up haidut.
Unfortunately it is no breaking news indeed; seemingly the same with that recent study pointing towards 70-90% of some cancers being due to enviromental stimuli.
...At least it is known that many cancer drugs bring on dna damage and with single cell nuclei sequencing, you should be able to prove/notice that easily.
Let's hope for a change soon.
 

mrsvacasey

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My mum has highly likely got colon cancer (huge lump, symptoms, awaiting diagnostics) - so 15mg Vit k2 but how do I get that much Caffeine into her? Di you need to build up? She isn't tolerating sweet things (watery diarrhoea) so if we ramp up her metabolism with Caffeine how can she cope?

:/
 

dookie

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My mum has highly likely got colon cancer (huge lump, symptoms, awaiting diagnostics) - so 15mg Vit k2 but how do I get that much Caffeine into her? Di you need to build up? She isn't tolerating sweet things (watery diarrhoea) so if we ramp up her metabolism with Caffeine how can she cope?

:/

What about applying the coffee "topically" directly to the tumor, by using coffee enemas? Gerson would have terminally cancer patients, often underweight and coming in on crutches, do a coffee enema every 4 hours, made from boiling about 3 tablespoons of coffee with 1 liter of water. Sometimes he'd have patients wake up in the middle of the night, to do a coffee enema. Maybe all those coffee enemas would average up-to 1500 mg of caffeine. He would then also feed patients fresh raw fruit and vegetable juices, I think the protocol says something like 1 gallon of freshly squeezed juices per day.

If terminally ill cancer patients, who we'd consider frail and weak, can be made to tolerate 1500 mg of caffeine, well then what about the rest of us
 

kayumochi

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Oct 7, 2015
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Both chemotherapy , radiotherapy AND surgery have long been known to enhance tumor spreading in the long term.

Eli Jones (1850-1933) recognized surgery was detrimental to the cancer patient, and used cancer herbal salves to achieve outstanding cure rates.
In 1911, before retiring, he compiled a book about his methods: Cancer - Its Causes, Symptoms and Treatment (free to download at archive.org: Cancer: Its Causes, Symptoms & Treatment, Giving the Results of Over Forty ... : Eli G Jones : Free Download & Streaming : Internet Archive)
Eli Jones - Wikipedia

Today, cancer specialists scare the bejesus out of you and don't give you any reflection time. 85% of people cannot manage their own health and would never distrust a doctor.

The bigger the lie, the more believable.

There's a lot of deliberate misinformation on the net about alternative cancer therapies, just as there a lot of excellent info.

The problem is having the time to sift through it (while you're dying).

there is a billboard of a local hospital system that claims to take it's patients "from diagnosis to treatment in 3 days" ... it scares me everytime I see it
 
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