I also happen to be taking 4 of the $0.88 Walmart 325mg pills, 1.3 grams, every day. I figure since I take plenty of K2 (and collagen) that there would be nothing wrong with that dose. Are there any downsides besides the risk blood thinning or GI upset? Heck, I used to take 5-6 of them because of the uncoupling thread and wanted to see if it would cause fat-burning via increased metabolism. Didn't seem to notice any "uncoupling" effect so I just take one with every meal and one at bedtime for prevention of diseases such as cancer and counteract inflammation from the HIV medicine and hopefully provide better metabolism for my hair follicles.