Cancer cells can "infect" healthy cells and convert them

haidut

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Ray was written many articles on the "cancer field" and how there is no such thing as localized tumor. Trying to cut the tumor or kill it with radiation and chemotherapy invariably causes it to reoccur, and often also metastasize. Ray keeps stressing the long term interactions of cells and how important they are to health. Every cell in the organism is probably aware of the health status of all other cells.

http://www.sciencedaily.com/releases/20 ... 113910.htm

"...Several factors expelled by tumor cells are concentrated in the area immediately surrounding the tumor, called the tumor microenvironment. While it is established that these factors support and enhance cancer cell growth and multiplication, it was not known whether these factors influence neighboring normal cells. Now a team of researchers from the University of Delaware, Nemours/A.I. duPont Hospital for Children, St. Joseph's Hospital and Medical Center in Phoenix and Therapy Architects LLC in Wilmington, Delaware, has reported that cancer cells can actually cause neighboring normal cells to become cancerous. The research is documented in the current online edition of the Journal of Cell Science.

"...Ayyappan Rajasekaran, University of Delaware adjunct professor in materials science and engineering and president of Therapy Architects, says this is the first time research has demonstrated that a cancer cell can sequentially induce early and late stages of cancer development in neighboring normal cells--a fundamental finding that can inform future studies."

"...Like bacteria and viruses, cancer cells have the potential to infect normal cells and promote cancer progression," he adds. This finding opens up new cancer research areas, including determining how cancer cells interact with neighboring normal cells and promote cancer development."

"...From a clinical perspective, the discovery raises the question of whether reducing sE-cad levels in cancer patients will slow the progression of cancer and improve treatment options. "These future studies should give a new dimension to our understanding of cancer development and treatment," Rajasekaran says."

As you can see the lead scientists hypothesizes that reducing levels of sE-cad levels may be therapeutic. And since this would not be Peat-friendly post without the honorable mention of such a substance, here is a study showing that aspirin inhibits the effects of sE-cad and thus prevents tumor dissemination into neighboring cells.
http://link.springer.com/article/10.1007%2FBF02710369

"...In testing this system we observed that acetylsalicylic acid blocked the endothelial activation induced by soluble products secreted by tumour cell by: a) impeding the translocation of NF-κB; b) reducing the expresion of ICAM-1, and c) reducing the capacity of endothelial cells to adhere to the human lymphoma U937. These results can explain, in part, the mechanism by which acetylsalicytic acid impedes the dissemination of malignant tumours.
 
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haidut

haidut

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Hugh Johnson said:
post 112526 Doesn't the conversion go both ways? As in if you put a cancer cell into a healthy environment it becomes normal.

Exactly! So far I have posted studies on thyroid hormone and aspirin triggering such "normalization" of cancer.
viewtopic.php?f=75&t=3637
viewtopic.php?f=108&t=6763

I suppose that the more general statement would be that pro-energetic substances reverse the cancer phenotype. Non-chemical approaches like red light and depletion of PUFA should have similar effects.
 
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hmac

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My grandmother has had what has been coined 'pre-cancerous lesions' on the skin of her arms and legs which have been being 'monitored' by a 'specialist' for the last year or so. I bought her some progesterone to apply to the areas and they healed completely in 3 days. Not that this will come as a surprise to anyone on the forum, but this seems to prove that progesterone can reverse the cancer phenotype.
 
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haidut

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hmac said:
post 112609 My grandmother has had what has been coined 'pre-cancerous lesions' on the skin of her arms and legs which have been being 'monitored' by a 'specialist' for the last year or so. I bought her some progesterone to apply to the areas and they healed completely in 3 days. Not that this will come as a surprise to anyone on the forum, but this seems to prove that progesterone can reverse the cancer phenotype.

That's awesome! Thanks for sharing. Adding just a little DHEA may make this even more effective. As little as 1mg topically on the lesions together with progesterone should suffice. Caffeine and aspirin, both topically are also great for skin conditions.
 
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hmac

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haidut said:
post 112631
hmac said:
post 112609 My grandmother has had what has been coined 'pre-cancerous lesions' on the skin of her arms and legs which have been being 'monitored' by a 'specialist' for the last year or so. I bought her some progesterone to apply to the areas and they healed completely in 3 days. Not that this will come as a surprise to anyone on the forum, but this seems to prove that progesterone can reverse the cancer phenotype.

That's awesome! Thanks for sharing. Adding just a little DHEA may make this even more effective. As little as 1mg topically on the lesions together with progesterone should suffice. Caffeine and aspirin, both topically are also great for skin conditions.

Thanks - I'll add the Dhea if they come back but but at the moment it isn't necessary as there's nothing to put it on! I'm keen, generally, to try more of thes things to help her; her issues are pretty much a textbook example of the situation described in every one of Peats articles: edema, osteoporosis etc etc. In fact, in general, it has been very painful to watch the way she has been treated - being knowledgeable about the concepts expressed on this forum and by Peat really made me aware of the senselessness of conventional methods. Watching her being 'ventilated' with pure oxygen during a time of intense pulmonary edema was particularly frustrating as I was well aware that the cause of edema can be partly due to insufficient CO2 which pure oxygen would make even more unavailable to the tissues.

Anyway, back to the original discussion...
 
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