1. Cocoa Butter - Organic & Fair Trade Certified
    CLICK HERE!
    Dismiss Notice
  2. **NEW** BL11 - Orange, Red & Infrared Therapy Body Light
    CLICK HERE!
    Dismiss Notice
  3. Charcoal Soap - For Deep Cleansing
    CLICK HERE!
    Dismiss Notice
  4. Orange & Red Light Therapy Device - LGS1
    CLICK HERE!
    Dismiss Notice
  5. Organic Cocoa Powder
    CLICK HERE!
    Dismiss Notice
  6. Metabasoap - Handcrafted Soap
    CLICK HERE!
    Dismiss Notice
  7. Cascara Sagrada Powder From Farmalabor In Italy
    CLICK HERE!
    Dismiss Notice
  8. **NEW Mini Body Light** MBL1 - Orange & Red Light Therapy Mini Body Light
    CLICK HERE!
    Dismiss Notice

It's Official - Cancer Surgery Drives Metastasis, Aspirin Can Prevent Them

Discussion in 'Scientific Studies' started by haidut, Apr 26, 2018.

  1. haidut

    haidut Member

    Joined:
    Mar 18, 2013
    Messages:
    15,591
    Gender:
    Male
    Location:
    USA / Europe
    The appearance of metastases has long been considered one of the most mysterious and important aspects of cancer due to the fact that metastases can occur even in organisms where the primary tumor has been completely removed and the rest of the organism has been completely isolated form the possibility of cancer cells infiltration. This has led to some scientists to propose the existence of a "cancer germ" of viral or bacterial origin that is capable of recreating the cancer in tissues very remote from the original cancer site. For the last 100 years the medical profession has vehemently denied any connection between the administered treatments and the appearance of metastases, despite the fact that untreated cancer patients rarely develop them, usually survive much longer, and often have those metastases regress spontaneously. I posted several studies linking the stress of surgery to the development of metastases, but the doctors I showed these studies to dismissed them as "commie crap" and not real science.
    Universal Test For Cancer Progression/Stage

    Other studies done in the West have implicated adrenaline in the metastatic process and anti-adrenaline drugs have been found to help. However, those studies on adrenaline did not point the finger directly at the cancer treatments as cause of metastases.
    Stress (adrenaline, Noradrenaline) As The Main Driver Of Cancer Metastases

    The study below finally makes the bold claim that cancer surgery directly triggers metastases by increasing inflammation, which is the natural response during wound healing. The mice used in the study that did not undergo surgery were remarkably resilient to development of both primary tumor and metastases but more than 60% of them developed metastases when operated on. The good news is that administering an NSAID drug completely prevented the development of those metastases AND growth of primary tumor (which surgery also promoted). Perhaps just as importantly, the study aptly notes that in women diagnosed with breast cancer, there are already thousands of micrometastases already present elsewhere, but those usually are kept in check by the immune system. Something seems to trigger their conversion into the highly aggressive and lethal form, and that something seems to be the very "treatments" administered by the whitecoats.

    The systemic response to surgery triggers the outgrowth of distant immune-controlled tumors in mouse models of dormancy
    "...Patients undergoing surgical resection of primary breast tumors confront a risk for metastatic recurrence that peaks sharply 12 to 18 months after surgery. The cause of early metastatic relapse in breast cancer has long been debated, with many ascribing these relapses to the natural progression of the disease. Others have proposed that some aspect of surgical tumor resection triggers the outgrowth of otherwise-dormant metastases, leading to the synchronous pattern of relapse. Clinical data cannot distinguish between these hypotheses, and previous experimental approaches have not provided clear answers. Such uncertainty hinders the development and application of therapeutic approaches that could potentially reduce early metastatic relapse. We describe an experimental model system that definitively links surgery and the subsequent wound-healing response to the outgrowth of tumor cells at distant anatomical sites. Specifically, we find that the systemic inflammatory response induced after surgery promotes the emergence of tumors whose growth was otherwise restricted by a tumor-specific T cell response. Furthermore, we demonstrate that perioperative anti-inflammatory treatment markedly reduces tumor outgrowth in this model, suggesting that similar approaches might substantially reduce early metastatic recurrence in breast cancer patients."

    "...As we repeatedly observed, surgically wounding tumor-bearing mice at a distant anatomical site triggered a substantial increase in the outgrowth of these immunologically restricted tumors. Surgery-induced tumor outgrowth was associated with a local and systemic inflammatory response characterized by the release of cytokines and the mobilization of myeloid cells into the circulation of wounded mice. Specifically, our data implicated inflammatory monocytes, which differentiate into macrophages inside tumors, as likely functional mediators of the systemic response to surgery. Collectively, our results indicate that systemic inflammation initiated as part of the wound-healing response following tumor resection surgery is likely to contribute significantly to the sharp peak in early relapse."

    Cancer surgery can awaken tumor cells, but cheap pill halts spread in mice
    "...Bottles of aspirin and ibuprofen won’t soon be carrying labels saying they reduce the risk of breast cancer recurrence after surgery, but that kind of cheap drugstore remedy stemmed metastasis in a startling new study in mice. Although lumpectomy is often curative, in some cases it can activate tiny, distant tumors that had been held in check, sometimes for years, by the immune system. Plain old penny-a-pill NSAIDs (nonsteroidal anti-inflammatory drugs) like aspirin, however, can prevent the immune system from letting down its anti-cancer guard, according to a study on lab mice published on Wednesday in Science Translational Medicine. Recent studies have found that even the most beneficial mainstream therapies have a dark side. Chemotherapy before breast cancer surgery, for instance, might fuel metastasis in some patients; chemo can also make malignant cells that survive treatment more aggressive."

    "...They injected lab mice with aggressive breast cancer cells. When the cells had characteristics that made the mice’s immune system attack them, almost all the animals — up to 90 percent — rejected the cancers as vigorously as they would a mismatched organ transplant. That suggested that when the immune system is fired up, it can keep tiny malignancies in check, by unleashing cell-killing white blood cells called CD8+ T cells. That finding may explain one big puzzle: About 35 percent of women diagnosed with breast cancer already have thousands of micrometastases, Weinberg said, but only half of them eventually develop metastatic, life-threatening cancer. In the lucky half, the immune system might be controlling the dangerous cells. “There are tumors that are doomed to be rejected by the immune system,” Weinberg said. “We wanted to ask, what mechanisms awaken previously dormant micrometastases?”"

    "...After doing the surgery, the scientists examined breast cancer cells that had been injected in the mice. In mice that underwent surgery, 60 percent of the cells kept growing and formed tumors. In mice that did not have surgery, only 10 percent did. Based on results from 273 mice, the scientists concluded, “surgical wounding” can promote the growth of metastasized breast cancer cells previously held in check by the immune system."
     
  2. Janelle525

    Janelle525 Member

    Joined:
    Sep 13, 2012
    Messages:
    2,595
    Yes surgery can disrupt cells. I have a friend who had an appendicitis that went gangrene by the time she went in. A year later she developed more pain in the area and turns out it was cancer of the intestine. She went through the typical surgery and chemo, and is barely alive today as the cancer had spread and they couldn't get the wounds to heal in the intestine, so they kept opening her back up and putting her on IV nutrition because she couldn't eat. This has been going on for 3 yrs. She just had another surgery to remove most of her intestine because it wasn't healing. I don't know how much longer she can take not having any sustenance from food. It's miracle she has even survived all this trauma.
     
  3. lollipop

    lollipop Guest

    So sad. Sending good thoughts.
     
  4. Jem Oz

    Jem Oz Member

    Joined:
    Jun 13, 2016
    Messages:
    122
    Gender:
    Male
    Can anyone explain to me the difference then between the clearly negative effects of tumor removal, and the supposedly positive effects of micro-needling? Why does one promote devastating inflammatory responses, and the other supposedly positive re-growth/healing? Is it just a question of degrees?
     
  5. KDub

    KDub Member

    Joined:
    Oct 24, 2017
    Messages:
    13
    Ray has a very thorough article on Cancer here: Cancer: Disorder and Energy. The gist is that someone with tumors is already in a highly inflamed state, and the surgery adds fuel to the fire. However, in a healthy person, a little extra stress signaling may not be a big burden. So, while needling may help with scarring, wrinkles, etc., I haven't seen anything in my research that would indicate that it is beneficial for the body overall. More likely that it is a manageable burden for the body, but results in some favorable aesthetics.
     
  6. Jem Oz

    Jem Oz Member

    Joined:
    Jun 13, 2016
    Messages:
    122
    Gender:
    Male
    Ah thanks for that @KDub. Makes sense.
     
Loading...