gaba

  1. Mauritio

    GABA decreases flouride inuced hypothyroidism; more effective than thyroid hormone

    This study shows that GABA increases thyroid hormones that were downregulsted from fluoride ingestion in mice . This shows what a pro metabolic and protective effect GABA has on the body . So people drinking high fluoride water might want to stack up on GABA for thyroid protection . "Subacute...
  2. R

    Verbascoside (from cistanche) has anxiolytic and hypnotic effects in rat model, potentially due to GABAAR interaction

    https://pubmed.ncbi.nlm.nih.gov/28884085/
  3. Hans

    Want Great Boners Without Viagra? Try This Stack Out For Size (pun Intended)

    Just to be clear, this article is about boners (no R rated content though). In this article, I share a potent stack that I've found to work great for powerful and long-lasting erections. Want great boners without Viagra? Try this stack out for size (pun intended) » MENELITE If you do give it a...
  4. BigYellowLemon

    Salt Enhances/potentiates GABA

    The study is a bit specific but it shows in essence that GABA is dependent on salt (sodium chloride) to function, and that the strength of GABA activation in the mammalian body can be controlled to an extent by controlling salt intake. It also is another piece of evidence showing the...
  5. M

    "The GABA System, Defences, And Tissue Renewal"

    The following snippets are taken from Ray's newsletter from 2008. "Protective inhibition is one of the most important principles in biology. Heart disease, cancer, anxiety, allergies, epilepsy, degenerative nerve diseases, endocrine disorders, inappropriate inflammation and shock all involve...
    • metabolizm
    • Thread
    • gaba
    • Replies: 15
    • Forum: Health
  6. haidut

    Insects Can Feel Both Acute And Chronic Pain, Can Even Develop Insect-PTSD

    Probably not many forum users know it, but to this day surgery on babies or other painful procedures is often performed without anesthesia. The rationale for this horrific torture is that the nervous system of babies is not developed yet, so they don't feel pain. It takes a special kind of...
    • haidut
    • Thread
    • acute animals chronic feel gaba glycine inhibitory insects neuropathic pain ptsd
    • Replies: 4
    • Forum: Scientific Studies
  7. haidut

    Allopregnanolone May Soon Be Approved As A Fast-acting Antidepressant

    The patents on most SSRI drugs have either expired or are close to expiration. Lately, there have also been a number of high profile cases obtaining favorable court outcomes by blaming SSRI drugs for a host of human criminal behaviors or adverse health events. As such, Big Pharma is desperate to...
    • haidut
    • Thread
    • 5a-dhp allopregnanolone antidepressant approval brexanolone fast-acting fda gaba mental health mental illness mood progesterone steroid
    • Replies: 67
    • Forum: Scientific Studies
  8. haidut

    GABA And Glycine Have The Same Effects In The CNS

    I am posting this simply as a pointer for those that suspect they have GABA signalling deficiency. Accodring to this study, instead of supplementing with GABA (which is hard to find in good quality) supplementing with glycine may have the same effects/benefits. Peat spoke about the similarity of...
    • haidut
    • Thread
    • brain cns effects gaba glycine inhibitory interchangeable neurotransmitter same
    • Replies: 16
    • Forum: Scientific Studies
  9. haidut

    Intrusive / Unwanted Thoughts Due To Low GABA Signalling

    Peat has mentioned GABA quite a few times in his articles and its role as the chief inhibitory signal in the body, protecting both brain cells and peripheral tissues/organs from excitotoxicity caused by PUFA, glutamate, estrogen, stress, etc. But the role of GABA is especially prominent in the...
    • haidut
    • Thread
    • anxiety depression gaba intrusive thoughts psychosis ptsd schizophrenia unwanted thoughts
    • Replies: 47
    • Forum: Scientific Studies
  10. haidut

    Loneliness Increases Alcohol Tolerance, May Explain "addiction"

    I posted several studies in the past about the connection between stress hormones and "addiction", especially alcohol. This new study adds more evidence to that link and now also draws serotonin in the picture. Apparently, social creatures are much more sensitive to inebriation effects of...
    • haidut
    • Thread
    • addiction alcohol gaba gregarious isolation loneliness serotonin social isolation stress tolerance
    • Replies: 4
    • Forum: Scientific Studies
  11. P

    Evidence For A GABAergic System In Rodent And Human Testis: Local GABA Production And GABA Receptors

    Like dopamine and serotonin, gaba is not only active in the brain , it has peripheral functions too. Evidence for a GABAergic system in rodent and human testis: local GABA production and GABA receptors. - PubMed - NCBI Abstract The major neurotransmitter of the central nervous system...
  12. Steven Bussinger

    Insulin Neuroprotection And The Mechanisms

    Insulin Neuroprotection and the Mechanisms Insulin, Neuroprotection, GABA, Glucose, Glycogen, Ischemia, Glutamate Introduction Insulin is the only endocrinology hormone to decrease blood glucose. In addition, insulin serves as a growth factor, modulating mitogenesis, growth, and...
  13. haidut

    5α-Dihydroprogesterone (5α-DHP) - The Primary Progestogen Neurosteroid

    It has been shown that progesterone rapidly metabolizes into more saturated metabolites such as 5α-Dihydroprogesterone (5α-DHP) and tetrahydroprogesterone (also known as allopregnanolone or Allo). The enzyme 5-AR is the one responsible for the saturation, just as it is responsible for the...
    • haidut
    • Thread
    • 5α-dhp 5α-dihydroprogesterone alzheimer's antidepressant antiestrogen brain cns dementia gaba glycine ms neurosteroid parkinson's protective
    • Replies: 25
    • Forum: Scientific Studies
  14. haidut

    Stress Leads To Lower Dopamine And More Drinking

    The study was really on alcohol consumption what affects it. It has been known since the 1960s that people drink more when under stress but to this day mainstream medicine denies that there is a causative link between stress and substance abuse. I posted a few studies showing that "addicts" have...
    • haidut
    • Thread
    • addiction alcohol alcoholism cortisol crh dopamine drinking ethanol gaba glucocorticoid pregnenolone
    • Replies: 64
    • Forum: Scientific Studies
  15. haidut

    Androsterone - Anxiolytic, Sedative, And Anti-Convulsant Neurosteroid

    I just posted a thread about androsterone and its potent anti-depressant effects: Androsterone - An Andidepressant Neurosteroid Just like allopregannolone (ALLO), androsterone is 5-AR derived neurosteroid, and just like allopreganolone androsterone is a very potent GABA agonist (even more...
    • haidut
    • Thread
    • agonist androsterone anti-seizure anticonvulsant anxiety anxiolytic gaba sedation sedative
    • Replies: 29
    • Forum: Scientific Studies
  16. P

    Creatine Treatment Promotes Differentiation Of GABA-ergic Neuronal Precursors In Cultured Fetal Rat

    Creatine treatment promotes differentiation of GABA-ergic neuronal precursors in cultured fetal rat spinal cord. - PubMed - NCBI Creatine is a substrate of cytosolic and mitochondrial creatine kinases. Its supplementation augments cellular levels of creatine and phosphocreatine, the rate of...
  17. P

    Metabolism Of Galactose In The Brain And Liver Of Rats And Its Conversion Into Glutamate And Other A

    Metabolism of galactose in the brain and liver of rats and its conversion into glutamate and other amino acids. - PubMed - NCBI Abstract Time- and dose-dependent measurements of metabolites of galactose (with glucose as control) in various organs of rats are discussed. Not only the liver but...
    • paymanz
    • Thread
    • alzheimer's ammonia brain gaba galactose glutamate glutamine lactose study
    • Replies: 1
    • Forum: Scientific Studies
  18. haidut

    Brain Levels Of Gaba Predict Tactile Learning Ability

    This study is perhaps counter-intuitive to some given that GABA is the major inhibitory neurotransmitter in the CNS. However, GABA has repeatedly been shown to be crucial for the ability of the brain to learn and cholinergic drugs that were tried for Alzheimers failed spectacularly. For those...
  19. haidut

    Functional GABA Deficiency May Be Cause Of Autism

    This is one of the few studies on humans, and it showed that while levels of GABA in autistic and healthy children were similar, the activity of the GABA system was deficient in autism patients. This creates a functional GABA deficiency, which makes the autistic brain hyperexcited, as Ray has...
  20. E

    GABA High In Alzheimer ?

    "In this new study, Chen’s team discovered that the brains of deceased Alzheimer’s patients possessed abnormally high concentrations of an inhibitory neurotransmitter called GABA (gamma-aminobutyric acid)" http://www.iflscience.com/health-and-me ... discovered Is there any Peat perspective...
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