1. Mauritio

    Does bromocriptine cause heart issues ?

    This study included several thousand people and followed up with them after 10 years .The chance of developing valvualr heart disease was a tiny bit higher when on bromocriptine (0.34%) compared to the controll group which was 0.29%. "Within 10 years of follow-up, 11 patients (0.34%, 95% CI...
  2. Mauritio

    How prolactin causes hair loss

    The hair seems to be a target AND source of prolactin, this is what the researchers found in this study. They also showed that increasing prolactin in the hair follicle basically kills the hair follicle by removing it from the blood supply (a.k.a catagen phase). In my opinion prolactin is a...
  3. Mauritio

    Bromocriptine helps with Alzheimers

    Not surpsing, but cool that it's beeing researched. I suspect it's not just its D2 agonism, but also its Endotoxin / TLR4-antagonism. "Alzheimer's Disease (AD) is the most common neurodegenerative disease, which lacks disease-modifying therapeutics so far. Studies have shown that the...
  4. NewACC

    Sublingual usage of bromocriptine

    Hello, dear forum users. I went through every anecdote and every article about bromocriptine and did not find ANY mention, even the possibility, of taking bromocriptine sublingually. What are your thoughts on this? Will sublingual bromocriptine be more effective than oral bromocriptine weeks...
  5. haidut

    Blocking serotonin, promoting dopamine may reverse cardiovascular disease (CVD)

    The claim in the title stems from the fact that bromocriptine - the drug used in the study below - is an approximate 5-HT antagonist while also being full agonist on several dopamine receptors. IMO, the study is a monumental success since CVD is largely considered a progressive condition, for...
  6. NewACC

    Role of Cholinergic and Dopamine Receptors in the Physiology of Caffeine Tolerance

    Dear Forum Members, I found three interesting studies on reversing (or reducing) caffeine tolerance, by adding to chronic (or sub-chronic) caffeine treatment, either the dopamine agonists bromocriptine (a predominantly d2/d3 family agonist) or pergolide (a very potent d1 agonist), or...
  7. haidut

    Progesterone, bromocriptine may treat autism

    A great new study, which, while genomic in character, inadvertently points the finger directly at estrogen and/or serotonin as causes of autism. After all progesterone's main role in the human organism is as an estrogen (and cortisol!) antagonist, while bromocriptine is one of the oldest...
  8. S


    Quick question I see on the boards dopamine agonists being promoted. Some for good reason(medical reasons) but I see it being off label to promote well being, assisting in better help. With the potential of DAWS, is using something like bromocriptine wise for lowering prolactin levels...
  9. K

    What Is The Best Prescription Drug For Hyperprolactinemia?

    What is the best prescription drug for it? I see here doctors prescribe in general Carbergoline and rarely Bromocriptine? Is Bromocriptine better than Cabergoline? Has one more affinity to boosting serotonin than the other? Of there's isn't any issue like that. Are other types like Lisuride...
  10. haidut

    People Can Die As A Result Of Giving Up (a State Caused By Low Dopamine)

    Ask any doctor if loss of hope can kill and he/she will laugh in your face. Even if you use the more scientific term "learned helplessness" you will still be laughed out of the room. Well, the study below shows that "give-up-itis" (GUI) is quite real and can reliably kill a person if it takes a...
  11. Elchapchapchapo

    Awesome Bromocriptine Book By Lyle Mcdonald

    Read a lot of this today and figured it would be a great share for some. Contains a lot of info at bromocriptine. Have to thank @tyw for the heads up on this as I had seen it in one of his posts.
  12. A.R

    Which Is Better For Weightloss/Prolactin - Bromocriptine Or Lisuride?

    Because of high prolactin levels, weight gain seems to get accelerated. Was wondering if anyone has any experiences of using either of the two drugs, and which one would be most effective. Thank You
  13. haidut

    Dopaminergic Drugs Like Bromocriptine May Treat Alcoholilsm

    This study is interesting for several reasons. On one hand, it combines well with previous studies on addiction I posted about - i.e. that "addiction" is a physiological state in which a person attempts to mitigate the effects of "inescapable stress" as animal studies commonly call the issue...
  14. F

    Does Bromocriptine Improve Metabolism? Temps And Pulse Finally Up

    I've tried everything to get my pulse and temp up without it being from adrenaline and I mean everything, including Ritanserin, T4, T3, caffeine, etc. Nothing has brought them up until I took 1.25mg of Bromocriptine today for the first time. I thought I've read stuff where it could potentially...
  15. ecstatichamster

    Topical Bromocriptine Thread

    I've started topical bormocriptine, 1.25mg with DMSO, got the idea from a post by Haidut mentioning it. Day 3 now. Noticed good bowel movements, feeling good, maybe higher libido although it's always high. I'll keep you posted. Anyone else trying this or tried it?
  16. haidut

    LSD-derivatives Like Bromocriptine Can Fully Cure Breast Cancer

    Ray wrote about the usage of drugs like bromocriptine as an actual cure for certain types of cancer. He did not specify which cancers but given the causative role of prolactin in both breast and prostate cancer, I'd suspect these two were on his list. These studies below show that prolactin...
  17. haidut

    Bromocriptine Prevents CVD Events Associated With Type II Diabetes

    Your doctor probably does not know that bromocriptine is approved for the treatment of type II diabetes. Even if she/he did know about it, the cited mechanism of action is "unkown" or a "mystery". But at least, it is a step in the right direction - i.e. away from serotonin, estrogen and...
  18. haidut

    Prolactin Increases Cortisol Secretion

    I think this is a pretty important study as it provides further evidence of the close relationship between various biomarkers of stress such as prolactin, estrogen, and cortisol. As Ray said, estrogen is really not a female hormone but rather the stress hormone. Prolactin is pretty similar, and...
  19. haidut

    Bromocriptine Is Anti-obesity Agent & Reduces Nitric Oxide (NO) Synthesis

    Given the role of NO in endotoxin-inflammation-obesity axis, reducing NO synthesis would probably explain a good deal of bromocriptine's anti-obesity, anti-diabetic, and anti-cancer activity. If alpha-adrenergic "receptor" agonism was the main beneficial mechanism in bromocriptine's anti-obesity...
  20. haidut

    Dopaminergic Drugs Treat Ulcers Better Than Acid-blockers

    Many people on the forum are former or current users of PPI drugs or H2 antagonists. Most of these drugs (ith the possible exception of famotidine) have bad side effects that can persist years after a person stops taking the drugs. This study says that there is no need for taking those drugs...
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