aging

  1. P

    Biotin Accumulate In Adipose Tissue With Aging?(study) Biotin Inhibit Sirt1

    what do you think? Selective overexpression of human SIRT1 in adipose tissue enhances energy homeostasis and prevents the deterioration of insulin sensitivity with ageing in mice SIRT1, a longevity regulator and NAD+-dependent deacetylase, plays a critical role in promoting metabolic fitness...
  2. haidut

    Vitamin D3 Extends Lifespan By Preventing Toxic Protein Buildup

    Over the last 6-9 months I noticed that often people who communicate with Peat over email get a recommendation to supplement with vitamin D. When asked why, Peat said that he knows quite a few people who recovered from "very serious symptoms" by using vitamin D. Well, this new study shows that...
  3. P

    Potential Anti-aging Role Of Taurine Via Proper Protein Folding: A Study From Taurine Transporter Kn

    Potential Anti-aging Role of Taurine via Proper Protein Folding: A Study from Taurine Transporter Knockout Mouse - Springer Taurine is effective to several aging-related diseases. Taurine mediates a variety of biological actions, including osmoregulation and protein folding, which may...
  4. P

    NAD⁺ Repletion Improves Mitochondrial And Stem Cell Function And Enhances Life Span In Mice

    NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice. - PubMed - NCBI Adult stem cells (SCs) are essential for tissue maintenance and regeneration yet are susceptible to senescence during aging. We demonstrate the importance of the amount of the oxidized...
  5. haidut

    Vitamin K And D Reverse Muscle Aging, May Act Like Sports Doping Agents

    Vitamin D and K have a primary role in bone metabolism, together with calcium and the androgenic hormones. Ray has written about the importance of these vitamins not only for bone health but also for insulin sensitivity and accelerating deactivation of estrogen. Many of these beneficial effects...
  6. haidut

    HDAC Inhibitors Affect Every Function Of The Cell And May Extend Lifespan

    The use of HDAC inhibitors such as valproic acid or various butyrate salts for cancer treatment has been studied experimentally for decades. Until now, it was assumed that the process of histone acetylation and deacetylation affected mostly the processes associated with cell division and...
  7. burtlancast

    Life Supporting Substances - It's Rain Making Time, 2011-07-04

    Download link for the audio file: http://media.blubrry.com/itsrainmakingtime/p/itsrainmakingtime.com/_radioshows/110704Peat.mp3
  8. haidut

    Breakthrough In Understanding (and Potentially Reversing) Aging

    This studies only looked at skin cells but the mechanism is apparently present in all tissue cells and as such the scientists think that therapies can be developed not only for reversing skin aging but also systemic aging. Unsurprisingly, skin cell aging was found to be due to decline of...
  9. haidut

    Aging In Cells Is Driven By Mitochondria

    The process of aging is complex and according to mainstream science comes down to genes. Over the last few decades some scientists have discovered that genes probably do not play a major role but rather that aging comes down to processes in the mitochondria. However, until now, there had been no...
  10. haidut

    Ants Do Not Age Due To Living In Environment With High Co2

    Ray has written about this theory that the naked mole rat is a remarkably resilient creature that never gets cancer due to living in environment of very high levels of CO2. Coincindentally (or not), the naked mole rat is the only rodent that lives in colonies just like ants do. Anyways, this...
  11. haidut

    Lapodin - Liquid Emodin/β-lapachone Mix

    Peat has written many articles on the topic of quinones and their effects on metabolism / respiration. The earliest official work probably started around the time of William Koch in the early 20th century and continues to this day. Many people are familiar with the popular quinone CoQ10 but...
  12. haidut

    Estrogen (estradiol) Promotes Autoimmunity

    If there is any doubt in anybody's mind about the role of estrogen as a cause of autoimmune conditions I hope that his will clarify the situation some more. The excerpt below is from the study on adrenals and Alzheimers I posted today but I thought that this excerpt deserves its own thread given...
  13. haidut

    Alzheimer Patients Have "aged" Adrenals, Higher Cortisol And Estrone

    Ray has written several times about the changes that occur in the adrenals with aging and stress/hypothyroidism. The adrenal layers change in structure and activity in a way that favors zona glomerulosa, which results in higher production of cortisol and estrogen. This study seems to confirm...
  14. Mr Rossi

    Methylene Blue In Treatment Of Cancer, Aging & Dementia - Bernd Friedlander

  15. P

    Methylene Blue Delays Cellular Senescence And Enhances Key Mitochondrial Biochemical Pathways

    www.ncbi.nlm.nih.gov/pubmed/17928358 Abstract Methylene blue (MB) has been used clinically for about a century to treat numerous ailments. We show that MB and other diaminophenothiazines extend the life span of human IMR90 fibroblasts in tissue culture by >20 population doubling (PDLs). MB...
  16. haidut

    Blocking Inflammation From PUFA Reverses Brain Aging

    This study is important on several levels. First, it shows that it is possible to fully reverse brain aging. Second, it suggests that one of the main mechanisms for brain aging is inflammation induced by the primary metabolites of PUFA - the leukotrienes. I talked about them in my first show...
  17. charlie

    Statins: Heart Disease Drug Speeds Up Ageing Process, Warns New Research

    The hits keep coming...... :hattip Karl Denninger More at link: http://www.express.co.uk/life-style/hea ... se-warning
  18. haidut

    Aging Associated With A Loss Of Ability To Metabolize Glucose

    Ray has written about this phenomenon so many times, and it also underscores the futility of the attempt to cure diabetes by making people oxidize fat more. According to this study, with aging the human mitochondria progressively lose the ability to oxidize glucose. They can oxidize fat just...
  19. P

    Stimulation Of Skin's Energy Metabolism Provides Multiple Benefits For Mature Human Skin

    Stimulation of skin's energy metabolism provides multiple benefits for mature human skin. - PubMed - NCBI As an organism ages, there is a decline in mitochondrial function and cellular energy balance. This decline is both accelerated by and can cause the formation of reactive oxygen species...
  20. haidut

    Aging Tied To Loss Of Oxidative Capacity; Stress Has Same Effect

    In yet another confirmation of Ray's metabolic theory of everything (TOE), this study found that aging is associate with a shift from oxidative to reductive state in the cell. More importantly, the study found that stress has the same effects as the aging process - i.e. stress is a form of...
Back
Top Bottom