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aging
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The Dilemma Of Coronavirus Disease 2019, Aging, And Cardiovascular Disease
The Dilemma of COVID-19, Aging, and Cardiovascular Disease ....... ACE inhibitors, ARB inhibitors, ARDS Coronavirus is more severe and deadly in the aged, hypertensive, and diabetic. It is also of note that ATR-1 Receptors increase with age and are increased in cancer, diabetes...- md_a
- Thread
- aging cardiovascular disease covid-19
- Replies: 4
- Forum: Scientific Studies
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Vitamin E, Anabolic / Catatoxic Steroids, Egg Yolks Stop Soft Tissue Calcification And (maybe) Even
A great series of studies performed in the 1960s, with Hans Selye spearheading most of the investigations. It is amazing how much was known about human disease and aging, and how much of that knowledge has been so thoroughly forgotten to the point that doctors nowadays have never even heard of...- haidut
- Thread
- aging anacalciphylaxis calcification calcinosis calciphylaxis prevent progeria reverse soft-tissue calcification testosterone tocopherol vitamin e
- Replies: 29
- Forum: Scientific Studies
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Metabolic Dysfunction Is A Primary Cause Of Aging And Its Symptom Alzheimer Disease (AD)
As it seems, not all hope is lost when it comes to mainstream medicine. Just a few days ago I posted about a landmark human study with AD demonstrating that the a low daily dose of the cheap, unpatentable chemical methylene blue (MB) may stop AD. LSD may do the same, and both MB and LSD likely...- haidut
- Thread
- aging alzheimer's cure defect oxphos reverse
- Replies: 4
- Forum: Scientific Studies
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Increasing Metabolism May Reverse Alzheimer Disease (AD) And General Aging
Yet another study demonstrating the remarkable parallels between the decline in function (metabolism) and the structural abnormalities that occur not only in specific pathologies such as AD but also in the generalized degradation known as "aging". FDA currently does not recognize aging as a...- haidut
- Thread
- acetyl-coa ad aging alzheimer's energy mitochondria oxphos pdh reverse
- Replies: 3
- Forum: Scientific Studies
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Aging Likely Caused By Decreased Respiration / Metabolism, Not Genetic Mutations
It looks like after a century of utter idiotism in biology and medicine, those two disciplines may finally be getting on the right course. Despite the fact that the "rate of living" theory is still the dominant theory of aging in the halls of academia, a new generation of scientists is emerging...- haidut
- Thread
- aging deficiency downregulated epigenetic glycine mitochondria oxphos reduced respiration taurine
- Replies: 2
- Forum: Scientific Studies
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Estrogen And Cortisol, Not Androgens, Suppress Immunity
There is a very famous theory in reproductive biology still considered the dominant one in its field. Namely, males have to accept a trade-off between androgen levels and immunity. It is known as the immunocompetence handicap hypothesis (ICHH). Higher androgen levels, the theory goes, allow the...- haidut
- Thread
- aging androgen aromatase inhbitor atrophy cortisol dhea disease estrogen immunity progesterone suppression thymus
- Replies: 1
- Forum: Scientific Studies
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PUFA Are Immunosuppressive, Fasting And Protein Restriction (possibly) Even More So
Several great studies, which quickly illustrate the connection between PUFA, immune system, estrogen, cortisol, cancer and the protective role vitamin A/E play as well as their likely mechanism(s) of action. As I mentioned on one of the first podcasts with Danny Roddy, the role of PUFA as...- haidut
- Thread
- aging cancer disease fat immune system immunity inhbition pufa suppression toxic
- Replies: 0
- Forum: Scientific Studies
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Blue Light Accelerates Aging And Reduces Lifespan By More Than 50%
In one of his interviews, Peat mentioned that red light exposure may be the most fundamental protective factor in nature, and that a deficiency of it (as commonly seen in Western lifestyles) may be the main driver of systemic aging and the diseases associated with it. The study below provides...- haidut
- Thread
- aging blue light exposure lifespan light mitochondria neurodegeneration reduce shorten stress
- Replies: 13
- Forum: Scientific Studies
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Niacinamide May Restore Female Fertility In Old Age
The mainstream medical dogma is that after the onset of menopause, female reproductive potential is essentially zero. I posted a thread recently that challenged that dogma and demonstrated that infertility is essentially an energetic dysfunction process and can be reversed with exposure to red...- haidut
- Thread
- aging atp energy female fertility menopause nad niacinamide nicotinamide mononucleotide nmn
- Replies: 30
- Forum: Scientific Studies
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Mitochondria (energy) As The Main Driver Of Health, Intelligence, And Aging
We are finally starting to see Peat enter the mainstream and article like the one below are calling for a complete review of what we know about health and aging and how intelligence is tied to them. As the authors says, or actually borrows from Peat, there is solid evidence that mitochondrial...- haidut
- Thread
- aging atp chronic stress disease energy health intelligence mitochondria oxidative phosphorylation stress
- Replies: 17
- Forum: Scientific Studies
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Fertility Depends On Metabollism (ATP), Not Age
As many of you know, there are 2 fundamental dogmas in reproductive medicine. One is that every woman is born with a fixed number of eggs and those cannot be replenished. The second one is that there is a biological fertility clock in every woman that inexorably ticks, and if the female does not...- haidut
- Thread
- age aging atp eggs energy female fertility gonads lllt male ovaries pregnancy red light reproduction reproductive health testicles
- Replies: 17
- Forum: Scientific Studies
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Vitamin E Reduces Risks Of Cataracts By More Than 50%
Quite a few people have been asking on the forum and via email about interventions for age-related cataracts. Here are some links below. The type of vitamin E used in all studies was alpha-tocopherol and the dose varied from 12mg/day all the way up to HED of 15mg/kg daily for the rodent model...- haidut
- Thread
- aging alpha-tocopherol cataracts cloudification humans long term long-term use prevent reduce tocopherol treat vitamin e
- Replies: 4
- Forum: Scientific Studies
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Increased Cholesterol Esterification As A Cause Of Alzheimer Disease (AD)
Peat's most recent newsletter was on the topic of cholesterol and its increased esterification as a possible cause of the many pathologies that occur with aging. Nov 2018: Dr. Peat Talks About Cholesterol Esters Causing Aging One of the organs most vulnerable to cholesterol esterification is...- haidut
- Thread
- ad aging alzheimer's cholesterol dementia ester esterification esters increase thyroid
- Replies: 8
- Forum: Scientific Studies
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Low Dose DHEA Powerfully Shifts The Redox Status Towards Oxidation
A great study, which shows that low-dose DHEA in the range discussed here on the forum (about 15mg daily) not only completely reversed the reductive stress seen in very old mammals but put the aging animals in an even more oxidized state than their very young counterparts. This study matches...- haidut
- Thread
- aging cancer dhea g6pd g6pdh gsh gssg oxidation redox shift
- Replies: 22
- Forum: Scientific Studies
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There Is Probably No Limit To Human Lifespan
The current ruling dogma in medicine is that human longevity is most likely genetically determined, and seems to be capped at about 125 years. The main arguments given in favor if this hypothesis are the apparently exponentially rising odds of dying with increasing age and the fact that no...- haidut
- Thread
- aging human immortality indefinitely lifespan lifestyle longevity unlimited
- Replies: 91
- Forum: Scientific Studies
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New Human Trial With An NAD Precursor
I just wanted to post this here, as it seems interest in raising NAD is high among pharma companies. While nicotinamide riboside is the most popular precursor used in the Western world, nicotinamide mononucleotide (NMN) is another one that has been used clinically. This clinical trial below...- haidut
- Thread
- aging human low dose mitochondria nad niacinamide nicotinamide mononucleotide steroidogenesis trial
- Replies: 15
- Forum: Scientific Studies
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Reducing Estrogen Synthesis Regenerates Thymus Destroyed By Aging
Recently, I posted a thread showing that immune dysfunction (thymus shrinkage) which developed with aging (and excess of PUFA, estrogen, cortisol) explains cancer incidence much better than any genetic model. Immune Dysfunction (cortisol/estrogen/PUFA), Not Genetics, Causes Cancer The quote...- haidut
- Thread
- aging aromatase aromatase inhibition dht estrogen progesterone spleen testosterone thymus
- Replies: 10
- Forum: Scientific Studies
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Cardenosine - Liquid Product For R&D
Our new product is finally here and it is "all about the ATP". I mentioned quite a few times on the forum and over email that we plan on releasing an ATP product and people have been asking me about it for the last few months. It seems a very simple task at first but we thought that we can do a... -
Immune Decline (Not Genetics) Causes Cancer And It Can Be Easily Fixed
As most of the forum users know, the genetic dogma reigns supreme in the oncology field. Despite many recent studies showing cancer rates in young people are increasing and that increase cannot be explained by genetics, the mainstream view is still very much along the lines of "bad" mutated...- haidut
- Thread
- aging cancer cortisol estrogen genes immune dysfunction immune system mutation progesterone pufa thymus warburg effect
- Replies: 8
- Forum: Scientific Studies
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Colon Aging / Cancer? Due To Low NAD / High Serotonin; Niacinamide Reverses Both
Peat has said many times that the impaired bowel regularity that occurs in aging, hypothyroidism and various pathologies is due to high NO and serotonin. He also said that while serotonin inhibits motility in the colon it increases it in the small intestine. Most doctors do not agree with that...- haidut
- Thread
- 5-ht4 aging colon colon cancer niacinamide nmn serotonin serotonin uptake sert tph tph2
- Replies: 33
- Forum: Scientific Studies