• Due to excessive bot signups along with nefarious actors we are limiting forum registration. Keep checking back for the register link to appear. Please do not send emails or have someone post to the forum asking for a signup link. Until the current climate changes we do not see a change of this policy. To join the forum you must have a compelling reason. Letting us know what skills/knowledge you will bring to the community along with the intent of your stay here will help in getting you approved.

Vitamin D improves ovarian reserves in women with infertility


Mar 18, 2013
USA / Europe
Diminished ovarian reserves are one of the major causes of female infertility. It used to be a problem mostly in women over 45 who were trying to get pregnant, however, it has now become a common finding even in 30+ year-old females. Estrogen is known to play a big role, and some studies have demonstrated beneficial effects of aromatase inhibitors. More recent studies have also demonstrated robust benefit from DHEA supplementation, and some fertility centers now use DHEA as part of their treatment protocols for women. Unfortunately, often the doses used are way too high and end up elevating estrogen, so that the net benefit is either minor or entirely absent. The study below offers one alternative to DHEA that is probably less risky. It demonstrated that weekly supplementation with 50,000 IU vitamin D increased ovarian reserves and increased pregnancy rates. A quick look at the results suggests the improvement was similar in magnitude to the one observed with DHEA, but obviously without the risk of raising estrogen. As such, I don't see why a combination of vitamin D and DHEA would not be synergistic, especially considering that vitamin D is a steroid with anti-estrogenic effects and is known to synergize with other steroids, especially androgens such as DHEA.

Does vitamin D supplementation improve ovarian reserve in women with diminished ovarian reserve and vitamin D deficiency: a before-and-after intervention study - BMC Endocrine Disorders
Does vitamin D supplementation improve ovarian reserve in women with diminished ovarian reserve and vitamin D deficiency: A before-and-after intervention study | MDLinx

"...Researchers conducted the study for analyzing the effect of vitamin D supplementation on ovarian reserve in women with diminished ovarian reserve and vitamin D deficiency. The study is a before-and-after intervention study on women with a diminished ovarian reserve who were referred to the Shahid Mofteh Clinic in Yasuj, Iran. Eligible women were given vitamin D tablets at a weekly dose of 50,000 units for up to 3 months. At the end of 3 months, serum levels of vitamin D and anti-Mullerian hormone (AMH) were assessed. The current study's findings support a possible beneficial effect of vitamin D on increasing AMH expression by acting on the AMH gene promoter. As a result, vitamin D may raise AMH levels without affecting antral follicle count/ovarian reserve."
Last edited:

Kaur Singh

Mar 20, 2021
Good timing!

Would you know approaches to address early onset peri-menopause
(as in a good decade or decade and a half early)
asides from the general advise for restoring mitochondrial and thyroid function?

is there something specific that may bring benefit?
(I'm working on D already)

I ran an antimullerian hormone test two years ago
and was quite quite low, almost zero.

If anything, I find that I need higher doses of progesterone.
Similar threads
Thread starter Title Forum Replies Date
raypeatclips Vitamin D Supplementation Improves Colon Cancer, Does Not Cause Hypercalemia Scientific Studies 57
J Vitamin C Raises Body Temperature And Improves Cold/heat Tolerance Articles & Scientific Studies 1
W Chronic Vitamin E Administration Improves Brachial Reactivity And Increases Intracellular Magnesium Scientific Studies 6
M Vitamin D Improves Heart Function (BBC, ScienceDaily) D 3
Gabriel CLA, A PUFA Found In Milk Fat, Improves Vitamin E Status Articles & Scientific Studies 2
aliml Increased activation of vitamin D (1,25D/25D ratio) is likely to be linked to disruption of the bone-kidney-parathyroid endocrine axis. Articles & Scientific Studies 3
sugarbabe *NEW* vitamin D information everyone needs to know! D 37
TypicalJock Does Vitamin E have any contributions to food intolerance? Digestion 1
BearWithMe Vitamin D supps might have shelf life as low as 2 weeks after opening? Ask For Help or Advice 7
Ippodrom47 You CAN get vitamin A toxicity from beta-carotene Scientific Studies 3
L Hypocupremia associated with prior vitamin B12 deficiency Scientific Studies 0
Mauritio Vitamin K, D and A bind to the SARS‐CoV‐2 spike protein Vitamins 28
Ippodrom47 Vitamin A and B12 interactions? Ask For Help or Advice 4
B Vitamin D relation with Cholesterol? Ask For Help or Advice 0
Xavage Peaty way to increase Vitamin K without supplementation? Ask For Help or Advice 8
RenaissanceMan Thoughts on Vitamin A Supplementation alongside T3? Ask For Help or Advice 0
Coffe Vitamin D3 and K2 timing Vitamins 6
E Vitamin D Palpitations (I already take magnesium) Ask For Help or Advice 14
IROM Just ordered Progest-Avail, BHRT Topical Pregnenolone in Vitamin E and BHRT Topical DHEA along with bulk Naringin and Chrysin. Supplements 1
A Why does Vitamin E gives me uterine cramps... Supplements, Pharmaceutical Drugs 4
Pina Proteolytic Enzymes vs Vitamin E - Reversing fibrosis and soft tissue calcification Ask For Help or Advice 38
CHEESEHEAD69 Looking for good quality vitamin d3 supplement cheap? Ask For Help or Advice 22
Coffe Time needed for optimum Vitamin D Vitamins 5
G Vitamin K Absolutely Changed My Face (Wow!) Ask For Help or Advice 13
sugarbabe Trouble going off vitamin C Ask For Help or Advice 77
haidut Vitamin D3 anabolic, calcitriol catabolic for muscle/thymus Scientific Studies 4
haidut Vitamin B1 and/or biotin may treat Huntington Disease (HD) Scientific Studies 35
CiggyTardust Vitamin D3 and Calcification D 14
Mauritio 4000 IU of Vitamin D increases Testosterone by 41% Vitamins 63
youngsinatra Anyone here feeling best on high calcium alone without vitamin D? Ask For Help or Advice 8
F Thyroid glandular vs thyroid meds is like comparing orange juice to vitamin C??? Ask For Help or Advice 2
Elize Vitamin patches Metabolism 5
E Anyone tried Vitamin K2 MK-9? Ask For Help or Advice 4
Braveheart More Evidence That Vitamin D Protects Against Severe COVID-19 Disease and Death D 9
haidut Vitamin A may treat anosmia (loss of smell) due to COVID-19 Scientific Studies 8
M Do policosanols and vitamin b1 have any interactions with other nutrients? how does thiamine affect methyl groups, other b vitamins and histamine? Ask For Help or Advice 0
Broken man Ameliorative effect of curcumin and vitamin B6 against lithocholic acid-induced cholestasis and liver injury in mice Scientific Studies 4
G Any drawbacks to dissolving pregnenolone w/o vitamin E Ask For Help or Advice 0
Hans Vitamin D3 and vit C resolved COVID-19 pneumonia in 3 days Scientific Studies 14
A COVID-19 and Vitamin A Ask For Help or Advice 4
Peatogenic Magnesium activates Vitamin D Testimonials 11
jpgio Vitamin E makes me feel alive Supplements, Pharmaceutical Drugs 11
E Vitamin D hypersensitivity Ask For Help or Advice 92
limitless77 Vitamin k2 mk4 vs mk7 and dosage? Supplements, Pharmaceutical Drugs 1
Braveheart The neuroprotective effect of vitamin E on chronic sleep deprivation-induced memory impairment E 0
Braveheart Excess vitamin intake: An unrecognized risk factor for obesity Vitamins 4
Mito Vitamin D and COVID-19 - Chris Masterjohn AHS 2021 D 26
miquelangeles Vitamin K and brain function K 3
haidut Vitamin D, reducing fat oxidation may treat lung fibrosis, COVID-19 Scientific Studies 19
haidut Human study - vitamin B1 safe & effective for preventing & treating Alzheimer Disease (AD) Scientific Studies 32

Similar threads