OP
Highserotonin90
Member
- Joined
- Mar 24, 2018
- Messages
- 794
Small update ... the first week of using Niacinamide had really helped me probably by increasing the NAD + and limiting the circulating fatty acids.
The difference was obvious.
Unfortunately after 7-10 days at a dosage of 100-150mg per day I suspect severe exhaustion within the Krebs or Sam-e cycle.
Practically the situation has worsened returning to the starting point.
Not having a pyruvate that enters Krebs regularly, using Niacinamide worsens the situation at a later time as vitamin B3 is present in it ... KREBS practically runs empty and methylation is also slowed down.
I also seem to be saturated with vitamin B1 HCL, I make it worse even at just 1mg in drops.
The TPP version makes me sick and I still don't understand why.
The only thing that is really working is the use of bioavailable version R Lipoic Acid in sodium.
It inhibits all 4 PDK complexes by setting the PDH in motion.
There is also biotin in it.
Any advice ... opinion ... is welcome. Thanks.
The difference was obvious.
Unfortunately after 7-10 days at a dosage of 100-150mg per day I suspect severe exhaustion within the Krebs or Sam-e cycle.
Practically the situation has worsened returning to the starting point.
Not having a pyruvate that enters Krebs regularly, using Niacinamide worsens the situation at a later time as vitamin B3 is present in it ... KREBS practically runs empty and methylation is also slowed down.
I also seem to be saturated with vitamin B1 HCL, I make it worse even at just 1mg in drops.
The TPP version makes me sick and I still don't understand why.
The only thing that is really working is the use of bioavailable version R Lipoic Acid in sodium.
It inhibits all 4 PDK complexes by setting the PDH in motion.
There is also biotin in it.
Any advice ... opinion ... is welcome. Thanks.
