More Evidence That Anti-depressants May Worsen Mental Health

Discussion in 'Scientific Studies' started by haidut, Sep 15, 2015.

  1. haidut

    haidut Member

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    I think at this point there is enough evidence to warrant putting quotes around the term "anti-depressants" since in many cases not only they do not improve mental health but may make the situation dramatically worse. This latest study adds even more weight to the evidence against the commonly used SSRI drugs.

    http://www.psypost.org/2015/09/antidepr ... rder-37574

    "...In a 2008 article in Journal of Affective Disorders, El-Mallakh described a condition he attributed to long-term antidepressant use which he called “antidepressant-associated chronic irritable dysphoria” (ACID). In the article, El-Mallakh cited a number of patients who took antidepressants for long periods of time and subsequently developed a consistent state of low mood, irritability and sleep disturbance. These symptoms were relieved when the patients discontinued antidepressants."

    "In a 2011 article in Medical Hypothesis, El-Mallakh analyzed data on patients whose depression initially improved with antidepressants, but later worsened. He hypothesized that some patients experienced a condition he called “tardive dysphoria,” in which antidepressants lose their effectiveness and may actually induce depression with long-term use."

    Yet, stunningly, the same scientist concludes that the "anti-depressants" are useful medications. Sounds very much like the assumption "PUFA is essential, therefore...".
     
  2. messtafarian

    messtafarian Member

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    It's kind of funny to look back and realize how naive we were when all these things were coming out. No one questioned at all how they were being tested or what they did, or what proof anyone had that "depression" even existed or how it was defined. Yet suddenly everybody was taking their pill because they were "depressed."
     
  3. tara

    tara Member

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    Breggins' Talking Back to Prozac came out more than two decades ago, I think?
    And Kathleen DesMaisons Potatoes not Prozac (though she was recommending potatoes and timing to increase serotonin by 'natural' means).
     
  4. mujuro

    mujuro Member

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    For those of us who have already been on antidepressants long term, what can we do about substituting it in the meantime or repairing the damage done?
     
  5. OP
    haidut

    haidut Member

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    Cyproheptadine has been successfully used in the past to wean people off of SSRI. Bromocriptine and other LSD-derivatives are probably also helpful.
     
  6. lexis

    lexis Member

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    There is a new article at Ray's site about serotonin
     
  7. Blossom

    Blossom Moderator

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    In addition to what haidut mentioned I have found pregnenolone helpful. I've been off antidepressants for coming up on seven years now and wasn't aware of Peat's work when I stopped taking them. Taking antidepressants is in the top three worst mistakes I've made in my life.
     
  8. Peata

    Peata Member

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    I know during the times I went on them, I felt good at first for I don't know how long - weeks, months, and then it kind of leveled off and I became more aware of the side effects, and they started to become more troublesome than the positive effects were worth. The last time I went on one though, it didn't help anything and only made me gain weight and have the usual side effects, plus high blood pressure for a time. I think I was in a situation of learned helplessness which made it worse.
     
  9. OP
    haidut

    haidut Member

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    Something to consider, for all women currently on or considering an SSRI:
    viewtopic.php?f=10&t=3251
     
  10. Such_Saturation

    Such_Saturation Member

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    That's an amazingly good description :ss I know a few who are like that.
     
  11. OP
    haidut

    haidut Member

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    That's like 90% of my coworkers, especially the older ones.
     
  12. Such_Saturation

    Such_Saturation Member

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    There seems to me to be a tendency to dismiss anyone who doesn't feel as bad as they do as some fool who doesn't see the whole picture. They often proclaim that "nothing matters", but apparently it matters that someone else can afford a smile every now and then :ss
     
  13. Makrosky

    Makrosky Member

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    I can relate to that thing after discontinuing Prozac. It lasted months.

    Do you guys think SSRI's like fluoxetine can up/down-regulate some receptors permanently ?
     
  14. lexis

    lexis Member

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  15. Such_Saturation

    Such_Saturation Member

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    And euphemisms :ss
     
  16. Blossom

    Blossom Moderator

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    Learned helplessness on their part perhaps?
     
  17. Such_Saturation

    Such_Saturation Member

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    Yes, it must be a very basic lack of energy in the brain I think. When you feel the "down" in your mind and in your gut for a long time it becomes impossible not to assume that philosophy, because nothing else makes sense.
     
  18. Frankdee20

    Frankdee20 Member

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    Only death is permanent
     
  19. Prosper

    Prosper Member

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    An unexpected sentiment from a man resurrecting dead threads.
     
  20. Frankdee20

    Frankdee20 Member

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    Lol, the irony indicates hope is near
     
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