As many of forum users know, one of the real mechanisms of action of the SSRI drugs is not the increased serotonin but the increase in brain...
Some people on the forum like @Wagner83 myself and a few others have tried the infamous herb TT with the hope of raising androgens and improving...
The patents on most SSRI drugs have either expired or are close to expiration. Lately, there have also been a number of high profile cases...
While the study is nothing new for the forum users here, what makes it important is that it is the largest study ever and includes reviewing all...
This study is really good because not only it states directly that depression can be directly caused by stress, but also because it shows that...
Peat was asked a few times about his opinion on SSRI drugs and he said that 1) he does not recommend them because they are systemically...
As I mentioned in a few threads before, I have always been interested in the so-called "reproductive aging", both in males and females. There is...
There is solid evidence that androgens have potent antidepressant effects in both sexes. However, the mechanism of action of that antidepressant...
As many of you know by now, I have acquired an interest lately to research the connection between the process of saturation of various nutrients...
It has been shown that progesterone rapidly metabolizes into more saturated metabolites such as 5α-Dihydroprogesterone (5α-DHP) and...
This was an animal study but it follows a long thread of other studies and some of them with humans. Unfortunately, so far all of the human...
I have always been suspicious of the annual reports of happiest countries around the world. I have visited quite a few of them (traditionally in...
EDIT: Since I keep getting questions about androsterone, here is Ray's response when asked about it: Ray Peat Email Advice Depository...
The neurosteroid DHEA has a well-known and studied anti-depressant effect. Several studies have been done in humans using relative high doses of...
Dopaminergic mechanism of antidepressant action in depressed patients. - PubMed - NCBIAbstractClinical studies have not yet determined a...
This study shows a number of key points central to Peat's views. Cortisol secretion is under the control of serotonin, and as such cortisol and...
I think at this point there is enough evidence to warrant putting quotes around the term "anti-depressants" since in many cases not only they do...
These studies were referenced by the gut-serotonin study I posted recently, and I thought they would be interesting to people here. The key point...
According to this study, aspirin in human equivalent doses of 250mg-500mg (maybe even higher given the administration was intraperrinoteal) is as...
How many of you have been on them, how many of you have gotten off of them and what were your experiences? If you did take them, how long did you...
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