antidepressant

  1. haidut

    Androsterone - An Andidepressant Neurosteroid

    The neurosteroid DHEA has a well-known and studied anti-depressant effect. Several studies have been done in humans using relative high doses of DHEA (50mg - 450mg daily) and they all found positive effects of DHEA on depression. Dehydroepiandrosterone monotherapy in midlife-onset major and...
  2. P

    Dopaminergic Mechanism Of Antidepressant Action In Depressed Patients

    Dopaminergic mechanism of antidepressant action in depressed patients. - PubMed - NCBI Abstract Clinical studies have not yet determined a common mechanism of action for antidepressant drugs, which have primary sites of action on a variety of different neurotransmitter systems. However, a...
  3. haidut

    Cyproheptadine As A Powerful Antidepressant

    This study shows a number of key points central to Peat's views. Cortisol secretion is under the control of serotonin, and as such cortisol and serotonin are high in depression. Most effective antidepressants are antagonists of serotonin and lower cortisol as well. This includes some the dreaded...
  4. haidut

    More Evidence That Anti-depressants May Worsen Mental Health

    I think at this point there is enough evidence to warrant putting quotes around the term "anti-depressants" since in many cases not only they do not improve mental health but may make the situation dramatically worse. This latest study adds even more weight to the evidence against the commonly...
  5. haidut

    Vitamin E (alpha Tocopherol) Is Effective Anti-depressant

    These studies were referenced by the gut-serotonin study I posted recently, and I thought they would be interesting to people here. The key point is that alpha tocopherol was most effective when administered chronically and at a relatively low dose of 10mg/kg for a mouse, which translates to...
  6. haidut

    Aspirin Is An Anti-depressant As Effective As Pharma Drugs

    According to this study, aspirin in human equivalent doses of 250mg-500mg (maybe even higher given the administration was intraperrinoteal) is as affective as pharmacological antidepressants. Effects of aspirin on immobile behavior and endocrine and immune changes in the forced swimming test...
  7. mandance

    Antidepressants

    How many of you have been on them, how many of you have gotten off of them and what were your experiences? If you did take them, how long did you take them for? Ray Peat often talks about the destructive effects of seratonin and estrogen, but I dont believe I have read anywhere about the long...
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