Evidence For Apo B Lipoproteins As The Root Cause Of Atherosclerosis


Dec 10, 2016
“A new paradigm for preventing atherosclerotic cardiovascula disease (ASCVD) is needed. The most recent US data show the long-term decline in cardiovascular deaths has stopped, and has started to increase in the most at-risk populations.1 Indeed, rising rates of obesity and diabetes mellitus in the setting of suboptimal risk factor control have resulted in a similar number of cardiovascular events occurring in those aged <65 years as ≥65 years.2 Although preventive drug therapies reduce the relative risk of cardio- vascular events in primary and secondary prevention patients, the absolute risk of subsequent ASCVD events remains high.3 If nothing changes, it is projected that by 2035 nearly half the US population will have some form of cardiovascular disease and costs will double to $1.1 trillion annually.”

“Compelling evidence supports evaluating intensive reduction of plasma apo B lipoproteins for regressing and perhaps curing early atherosclerosis. We have proposed the first human trial that will lay the groundwork for this new area of investigation into a new cardiovascular prevention paradigm aimed at eradicating the clinical burden of ASCVD. This new prevention paradigm combining an intensive induction-phase with long-term maintenance therapy should provide a maximum ASCVD prevention benefit with minimal inconvenience, adverse effects, and cost.”

Similar threads
Thread starter Title Forum Replies Date
md_a Further evidence supports controversial claim that SARS-CoV-2 genes can integrate with human DNA Scientific Studies 6
bzmazu "The Illusion of Evidence Based Medicine" Fraudulent ghostwritten Studies Breaking News 1
Arclight Anti-Peat Where is there good evidence that challenges the Central Dogma (and the safety of injecting foreign RNA)? Debate - Anti-Peat 5
Nehring In Vivo Evidence For The Anticancer Effect Of Thiamine / Thoughts On TTFD B1 16
M Personal Anecdotal Evidence Re: Coffee Consumption And Height Miscellaneous Health Discussions 45
L Covid-19, The Coverup, The Cure & Key Evidence Articles & Scientific Studies 0
S Evidence For Estrogen Levels In Mpb Hair & Nails 48
S Evidence For Estrogen Levels In Mpb Hair & Nails 38
F UK Telegraph: Lack Of Evidence Lockdowns Actually Worked Is World Scandal Viruses, Parasites, Fungus, Vaccines 7
E New Evidence That Higher Caffeine And Urate Levels Are Protective Against Parkinson's Disease Scientific Studies 2
Mito New Evidence That Higher Caffeine And Urate Levels Are Protective Against Parkinson’s Articles & Scientific Studies 0
S Covid-19: Evidence Over Hysteria Scientific Studies 24
ecstatichamster Dr. Peat Right Again: Losartan And Covid-19 Evidence For Efficacy Scientific Studies 63
charlie EXCLUSIVE: Evidence Shows Director General Of WHO Overstated The Fatality Rate Of The Coronavirus Breaking News 123
nigma Human Bodies Have Steadily Grown Colder Over The Past Century, Evidence Shows Scientific Studies 46
Mito First Evidence Of Immune Response Targeting Brain Cells In Autism Articles & Scientific Studies 3
E Scientific Evidence Non-ionizing Radiation From Mobile Phones Has Mental And Biological Effects Society 0
L Wherein Experts Rationalize Evidence That Contradicts What They 'Know' Scientific Studies 1
Lizb Liver Health, Hot Flushes. No Evidence For Remedy Here Female Issues 32
H Scientists Find First Evidence Of Humans Cooking Starches Articles & Scientific Studies 8
Mito Direct Evidence For Transport Of RNA From The Mouse Brain To The Germline And Offspring Articles & Scientific Studies 0
haidut There Is No "Depression Gene", Any "evidence" So Far Has Been Errors / Fraud Scientific Studies 1
L New Evidence Of Synergism Between Vitamins A And D — Can They Cure Diabetes? Fat-Soluble Vitamins 2
C Increased Excretion Of C4-Carnitine Species After A Therapeutic Acetylsalicylic Acid Dose: Evidence Aspirin 0
haidut DNA Evidence Can Be Completely Fabricated Society 0
Makrosky Porphyromonas Gingivalis In Alzheimer’s Disease Brains: Evidence For Disease Causation And Treatment Alzheimer's 2
Lokzo Current Evidence For The Involvement Of Sex Steroid Receptors And Sex Hormones In BPH Scientific Studies 0
haidut The Evidence Is Now CLEAR That Cell Phone Radiation (EMF) Causes Cancer Scientific Studies 167
P Evidence For Brain Sensing Of Circulating FFA Articles & Scientific Studies 0
Dan Wich KMUD: 9-21-2018 Evidence Based Medicine KMUD Radio-The Herb Doctors 8
S What Evidence Shows Estrogen To Be A Cause Of Hair Loss? Miscellaneous Health Discussions 56
Lokzo Evidence For Androgenic Activity Of Tumeric And Curcumin Scientific Studies 2
Mito Dietary Fat And Cardiometabolic Health: Evidence, Controversies, And Consensus For Guidance Articles & Scientific Studies 1
ddjd Anecdotal Evidence MSM Regrows Hair - Nitric Oxide Antagonist! Ask For Help or Advice 18
H Brain Scan Study Adds To Evidence That Lower Brain Serotonin Levels Are Linked To Dementia Scientific Studies 5
A More Evidence Essential Oils 'make Male Breasts Develop' Ray Peat Topics 10
D Evidence That Progesterone Raises Glutamate? Supplements, Pharmaceutical Drugs 1
AretnaP Did Gbolduev Have Any Evidence To Back Up His Claims About PH? Acidity vs. Alkalinity 216
dand "When Evidence Says No, But Doctors Say Yes Scientific Studies 2
ecstatichamster Evidence That Cortisol Really Does Cause Hair Loss Hair & Nails 339
ecstatichamster Evidence Of Traditional Long-fermentation Bread Being Healthier Vegetables, Grains, Legumes, Fiber 2
Mr. God of Cars Where Is The Evidence That Saturated Fats ___ Pyruvate Dehydrogenase? Metabolism 4
Mr. God of Cars What Is The Ray Peat's Evidence For Iron Being Necessary For Continued Growth? Diet 4
Soren More Evidence Parkinson's Starts In The Gut Digestion, Gut Flora 1
P Evidence For A GABAergic System In Rodent And Human Testis: Local GABA Production And GABA Receptors Articles & Scientific Studies 3
ecstatichamster Studies? Where Is Evidence PUFAs Are Preferentially Stored Not Burned? Science 25
haidut Solid Evidence That Stress Causes Obesity Scientific Studies 16
P Evidence For The Involvement Of 5-HT1A Receptor In The Acute Antidepressant-like Effect Of Creatine Articles & Scientific Studies 10
michael94 Carrageenan Evidence? Miscellaneous Health Discussions 11
burtlancast Looking For Scientific Evidence Of Steel Buildings Pancaking At Free Fall Speed. Anyone? Political Talk, Alternative World Theories 25

Similar threads