Is this a supplement worth taking in the Peat world!?
I'm taking this for viral reasons but ran into this during my research:
"Cat's Claw appears to have anti-estrogenic properties, as in a concentration dependent manner in vitro between 10-20mcg Cat's Claw noncompetitively inhibits the estrogen receptor (possibly by preventing formation of estrogen receptor complexes required for genomic signalling) with the higher concentration (20mcg) reducing binding of estradiol by 47.2%. [44] This was lesser than the active control of 20mcg Tamoxifen, a direct antagonist inhibiting 69.3% of signalling. [44]"
Depletion of specific binding sites for estrogen receptor by Uncaria tomentosa. - PubMed - NCBI
Depletion of specific binding sites for estrogen receptor by Uncaria tomentosa. - PubMed - NCBI
I remember Haidut mentioning that Tamoxifen wasn't very safe.
I'm taking this for viral reasons but ran into this during my research:
"Cat's Claw appears to have anti-estrogenic properties, as in a concentration dependent manner in vitro between 10-20mcg Cat's Claw noncompetitively inhibits the estrogen receptor (possibly by preventing formation of estrogen receptor complexes required for genomic signalling) with the higher concentration (20mcg) reducing binding of estradiol by 47.2%. [44] This was lesser than the active control of 20mcg Tamoxifen, a direct antagonist inhibiting 69.3% of signalling. [44]"
Depletion of specific binding sites for estrogen receptor by Uncaria tomentosa. - PubMed - NCBI
Depletion of specific binding sites for estrogen receptor by Uncaria tomentosa. - PubMed - NCBI
I remember Haidut mentioning that Tamoxifen wasn't very safe.