M
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the structure of carbamazepine is similar to imipramine , and we know how good imipramine is for anxiety. Carbamazepine same class as Lyrica for Epilepsy sodium blockers, carbamazepine happens to inhibit the Stress Signal (CRH) , this is like the best medication easiest to get I have found to inhibit the CRH and it does so where CRH is created - hypothalamus! In turn decreases CRH all over the brain and decreases CRF1 signaling which is responsible for feeling anxiety/fear. Carbamazepine aka tegretol has a long half life too!
'''' in vitro sutdies show that procaine is a potent stimulus to hypothalamic CRH release, while carbamazepine, a limbic anticonvulsant effective in the treatment of major affective disorder, inhibits procaine-induced in vitro CRH.''
'Carbamazepine has been shown to inhibit hypothalamic CRH secretion in vitro.''
'''' in vitro sutdies show that procaine is a potent stimulus to hypothalamic CRH release, while carbamazepine, a limbic anticonvulsant effective in the treatment of major affective disorder, inhibits procaine-induced in vitro CRH.''
'Carbamazepine has been shown to inhibit hypothalamic CRH secretion in vitro.''