"A hypothyroid person wastes sugar at a terrible rate" -RP

[EnergeticLeo]

Where is the article "insomnia and hyperactivity"?
I cannot find it in his articles.
Paul

https://wiki.chadnet.org/ray-peat; https://wiki.chadnet.org/files/insomnia-and-hyperactivity.pdf

 

[Apple]

https://wiki.chadnet.org/ray-peat; https://wiki.chadnet.org/files/insomnia-and-hyperactivity.pdf

Can we do something to make liver produce more T3 instead of directly supplementing ?

 

[AinmAnseo]

https://wiki.chadnet.org/ray-peat; https://wiki.chadnet.org/files/insomnia-and-hyperactivity.pdf

Thank you.

 

[learnedhelpless]

View attachment 57811
Can we do something to make liver produce more T3 instead of directly supplementing ?

Of course. The conversion of T4 to T3 relies on the health of your liver, and DHEA, Pregnenolone, Progesterone, Androsterone, etc, all increase the conversion.

 

[EnergeticLeo]

View attachment 57811
Can we do something to make liver produce more T3 instead of directly supplementing ?

Yep in addition to the above, you can do things that activate the bile acid receptor, which signal to the liver to increase T4 to T3 conversion


View: https://youtu.be/K9MIiN7nzWc?si=MnJSuJwGePEsi2bL&t=5815


So things like taurine, glycine, and TUDCA might work

 

[learnedhelpless]

Yep in addition to the above, you can do things that activate the bile acid receptor, which signal to the liver to increase T4 to T3 conversion


View: https://youtu.be/K9MIiN7nzWc?si=MnJSuJwGePEsi2bL&t=5815


So things like taurine, glycine, and TUDCA might work

I did not know this, thanks.
Haidut did a post about this aswell:

Bile Acid Stimulates Mitochondrial Function, Could Treat Parkinson And Alzheimer's

I posted a few studied some time ago showing that bile acids increase metabolism but stimulating the synthesis of T3. This increase in metabolism is perhaps the main mechanism behind the ability of "obesity surgery" to provide long-term benefits for the people who undergo the procedure. Aside...

raypeatforum.com

 

[EnergeticLeo]

I did not know this, thanks.
Haidut did a post about this aswell:

Bile Acid Stimulates Mitochondrial Function, Could Treat Parkinson And Alzheimer's

I posted a few studied some time ago showing that bile acids increase metabolism but stimulating the synthesis of T3. This increase in metabolism is perhaps the main mechanism behind the ability of "obesity surgery" to provide long-term benefits for the people who undergo the procedure. Aside...

raypeatforum.com

Cool, thanks for the link

 

[Mauritio]

Where is the article "insomnia and hyperactivity"?
I cannot find it in his articles.
Paul

4th result on google.

https://wiki.chadnet.org/files/insomnia-and-hyperactivity.pdf

 

[Apple]

Of course. The conversion of T4 to T3 relies on the health of your liver, and DHEA, Pregnenolone, Progesterone, Androsterone, etc, all increase the conversion.

Yep in addition to the above, you can do things that activate the bile acid receptor, which signal to the liver to increase T4 to T3 conversion
So things like taurine, glycine, and TUDCA might work

I may pose the question differently . Does that mean that so called hypothyroidism ( or Wilson's (temperature) syndrome or Broda Barnes definition of low thyroid) has more to do with the liver than thyroid gland per se ? I mean... for an average person, surely there are people with thyroid gland malfunctioning but an average RP forum reader may think ... - Doctor, I think my temperature is too low and heart rate below 60, something is wrong with my thyroid gland

As a side note, a key mineral for convertion T4 to T3 is Selenium. But I don't know if supplementing Se can really help. People usually supplement iodine which is no good without Se. Still it is advised to get your Se from foods because supplemeting Se directly is sort of an uncharted territory.

 

[learnedhelpless]

View attachment 57855

I may pose the question differently . Does that mean that so called hypothyroidism ( or Wilson's (temperature) syndrome or Broda Barnes definition of low thyroid) has more to do with the liver than thyroid gland per se ? I mean... for an average person, surely there are people with thyroid gland malfunctioning but an average RP forum reader may think ... - Doctor, I think my temperature is too low and heart rate below 60, something is wrong with my thyroid gland

As a side note, a key mineral for convertion T4 to T3 is Selenium. But I don't know if supplementing Se can really help. People usually supplement iodine which is probably no good Se. Still it is advised to get your Se from foods because supplemeting Se directly is sort of an uncharted territory.

They are both equally as important, but if I was forced to give an answer, I would say the liver is more important, as the reason, that T4 does not work for a lot of people, is that it doesn't get turned into T3 enough - so even with enough T4 being made in the thyroid gland, the liver still give hypothyroid symptoms. Furthermore, if your liver is working, then you will be excreting anti thryoid substances and hormones, even more.

And yeah, I haven't read that supplementing extra selenium (if you have a sufficient amount of it), will help, increase the conversion

 

[mgrabs]

They are both equally as important, but if I was forced to give an answer, I would say the liver is more important, as the reason, that T4 does not work for a lot of people, is that it doesn't get turned into T3 enough - so even with enough T4 being made in the thyroid gland, the liver still give hypothyroid symptoms. Furthermore, if your liver is working, then you will be excreting anti thryoid substances and hormones, even more.

And yeah, I haven't read that supplementing extra selenium (if you have a sufficient amount of it), will help, increase the conversion

If the liver is working the anti thyroid will release because of what? Giving too much thyroid hormone? What would that mean? Im a little confused sorry

 

[learnedhelpless]

If the liver is working the anti thyroid will release because of what? Giving too much thyroid hormone? What would that mean? Im a little confused sorry

The liver is in charge of excreting toxins in your body, so any things that reduce thyroid functions, like microplastics, will be excreted, at a faster rate.