dhea

  1. H

    DHEA Experiences

    I'd be interested to hear anyone's ideas on this / hear about experiences supplementing DHEA... Yesterday morning I took 5mg DHEA (Pure Encapsulations). Initially I felt it contributed to a generally positive and especially expansive mental state (although I have experienced this using lysine...
  2. haidut

    Why DHEA Must Be Taken In Small Doses Only

    Once again, I am amazed at how well Ray's recommendations are backed by science. He has said that taking DHEA is fine and can restore proper youthful hormone balance. However, he cautioned that DHEA should only be taken in doses of no more than 10mg at once and preferably no more than 15mg...
  3. haidut

    Dhea Inhibits Serotonin Synthesis Due To Stress Exposure

    DHEA seems to be an inhibitor of the enzyme TPH, which as we know synthesizes serotonin from tryptophan. It seems that, as per Peat's ideas, the serotonin increases from stress is due to cortisol. DHEA being a cortisol antagonist was able to block this effect. DHEA only had an effect when rats...
  4. haidut

    DHEA protects from endotoxin (even lethal doses)

    Yet another substance that can be used in cases of endotoxin overload. The study used 0, 1, 5, 25, 100 mg/kg DHEA doses in mice and lethal doses of endotoxin. The protection/survival from DHEA was dose dependent, but the biggest increase in survival was seen with the doses of 5mg/kg and 25mg/kg...
  5. haidut

    Low Dose DHEA Robustly Increases Oxidative Metabolism

    I posted another study recently that showed low doses DHEA treatment increased T and DHT levels in rats and had the same beneficial effects as exercise. The human equivalent dose used was <15mg per day. These studies shows that a low dose DHEA dramatically improves oxidative metabolism in liver...
  6. Strongbad

    Ginseng. DHEA, Pregnenolone And Peatarians

    I was browsing around for things that can enhance the effect on DHEA and pregnenolone and found Ginseng: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1421460/ Ginseng enhances the effectiveness of DHEA But at the same it's estrogenic. Maybe it's just the Korean and Asian ginseng...
  7. haidut

    DHEA Has Very Similar Anabolic Activity To DHT

    As a follow up to the studies I posted on DHEA increasing DHT in animals and thus improving metabolic parameters, this study compared the effects of DHEA and DHT on several human tissues and found them to be quite similar. Consequently, in lower doses DHEA may indeed convert mostly into...
  8. haidut

    DHEA Provides Same Benefits Effects As Exercise By Increasing DHT

    This is a follow up study to the one I posted earlier. This study by the same authors wanted to assess whether exercise was superior to DHEA administration in improving insulin resistance and blood glucose in obese rats. The results were that DHEA and exercise exert the same benefits and both...
  9. haidut

    DHEA as a potential treatment for Crohn's and UC

    The dose used was high (200mg) and the treatment lasted for about 2 months. I am not sure this is safe according to any standards given DHEA propensity to convert into estrone/estradiol, but may be an option for people not responding to other treatments or want to try something more Peat-y...
  10. haidut

    Low dose DHEA restores insulin sensitivity by increasing DHT

    This is one study that used doses of DHEA close to what Peat would recommend, and not the megadosing schedules likely to result in conversion into estrogen. The human equivalent dose was <15mg per day and resulted in 71% increases in DHT. It is that increase in DHT and DHEA levels that is behind...
  11. J

    Pregnenolone & DHEA Replenishment Dosage

    Hi everyone, I read on Ray Peat’s site at http://raypeat.com/articles/articles/th ... ones.shtml that Young people produce about 12 to 15 milligrams of DHEA per day, and that amount decreases by about 2 mg. per day for every decade after the age of 30. I also read that about 4MG of DHEA per day...
  12. sunmountain

    Dhea - Experiences Females?

    Ladies, I'd like to know your experience with DHEA. I'm taking 5mg at breakfast, and it's really good at helping me pee. I feel a lot less waterlogged. I switched back to DHEA after my pee became cloudy on diamox. BUT I think it might be causing insomnia. I've been sleeping pretty good for a...
  13. managing

    DHEA and lipolysis

    RP has been widely cited as recommending very small doses (2-3mg) of DHEA for diabetics. Presumably, this is to prevent low BG problems. But DHEA acts through lipolysis. http://www.ncbi.nlm.nih.gov/pubmed/18063002 http://www.ncbi.nlm.nih.gov/pubmed/7611511 Is it simply a lesser of two evils...
  14. Vinero

    Having Succes With DHEA

    After a year of using synthethic cortisol for some allergy issues i was having I was becoming colder and depressed every day, and unable to sleep and relax (my stupid docters recommendation) I decided to use DHEA after reading it was a glucocorticoid antagonist. I have been using it for two...
  15. J

    Progesterone vs. DHEA

    Peat thinks progesterone is a safe supplement. I wonder though if it could have bad effects by antagonizing DHEA. Peat mentioned that he cured moles using DHEA, so why couldn't progesterone make moles appear by antagonizing DHEA?
  16. Z

    DHEA Taller

    I just read an article that claimed Ray Peat grew 1.5 inches by taking DHEA. Is that physiologically possible? Have any of you heard of this?
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