TheSir
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- Joined
- Jan 6, 2019
- Messages
- 1,952
One is used as digestive aid the other as methylation supportOK then, what is the difference between Betaine and Betaine hydrochloride?
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One is used as digestive aid the other as methylation supportOK then, what is the difference between Betaine and Betaine hydrochloride?
This doesn't answer my question about what the differences are between the two.One is used as digestive aid the other as methylation support
What's an example of a pro-cholinergic effect?Hmm, I suppose if betain HCl just donates a hydrogen but then still stays as a salt? But I don't understand how that would survive digestion. I have felt very mild pro-cholinergic/methyl donating effects from betaine HCL, so I think that some of it probably makes it through.
I misspoke. It's not a pro-cholinergic effect, but rather the alleviation of choline/methyl deficiency. For me choline deficiency presents as insomnia, serious brain fog and confusion, slow digestion, and anxiety/heart palpitations. It's obviously intertwined with the methylation cycle, but having a deficiency or supplementing folate feels different. This is also obvious. Folate isn't only part of the methylation cycle, but also part of the biopterin cycle and more.What's an example of a pro-cholinergic effect?
Would this have similar effects to TMG?N,N-Dimethylglycine (DMG) is a methylated amino acid found in all cells, and is part of the biochemical pathway to synthesize glycine, a major building block for proteins and biological molecules.
TMG transfers its methyl group directly to homocysteine, while DMG uses the folic acid (methylfolate) pathway. Everything works together like a well-oiled machine, and in optimal circumstances, both TMG and DMG efficiently pump methyl groups into the methyl pool to produce SAM-e (S-Adenosyl methionine) from homocysteine. Having two paths to get methyl groups into pool is like having a fail-safe system. The fact that they use completely different systems to donate to the methyl pool also means that TMG might work better for one person, where DMG works better for another.
I decided to try TMG again because I had a suspicion it’s something to do with methylation