The Best Oral Magnesium Supplement

DANIEL

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Joined
Nov 10, 2020
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77
Highly recommend NutraBio Magnesium's supplement: great price and ZERO excipients, just got it a few days ago for $12 on Amazon.

Not affiliated with them, just wanted to spread the word.

This company in general has very cheap prices and usually does not use excipients, which is funny when you have companies like Thorne charging way more when they put silicon dioxide and other BS in their supplements.
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Frankdee20

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Jul 13, 2017
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Sun Coast, USA
Good product but for me, too low a dose... I’m requiring about 500-1000 MG daily to correct shoulder dyskinesia
 

LeeLemonoil

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Sep 24, 2016
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2,306
Magnesium lowers cortisol levels

Magnesium lowers cortisol levels



Here they used Mg-citrate, new one from 2020


By increasing your magnesium intake through your regular diet or supplements, you can increase the concentration of anabolic hormones like IGF-1 and testosterone, we reported earlier. But the hormonal positive effects of magnesium don't stop there. Magnesium supplementation can also lower cortisol levels, write Dutch nephrologists at the University Medical Center Groningen in Clinical Endocrinology.


Study


The researchers divided 49 healthy subjects aged 45-70 into 2 groups. The subjects in one group took a placebo every day for 24 weeks, while the subjects in the other group took 350 milligrams of magnesium citrate daily.


The supplement, which was made by the Dutch Medisan, [lab-medisan.com] provided 56 milligrams of elemental magnesium daily.



Results
During the supplementation period, the cortisol level in the experimental group dropped by approximately 32 nanomoles. This equates to a decrease of about 8 percent.












The table above has been reduced. Click on it for a larger version.



Mechanism
In the body, the enzyme 11-beta-HSH-type-2 converts the active cortisol into the inactive cortisone. The enzyme 11-beta-HSH-type-1 does the opposite, converting cortisone into cortisol.



The researchers were able to deduce from their measurements of various cortisone and cortisol metabolites in the subjects' blood that magnesium supplementation increases the activity of 11-beta-HSH-type-2.









Conclusion
"Previous studies have also suggested a role for cortisol in cardiovascular disease risk", write the researchers. "For instance, excess levels of cortisol in patients with Cushing's syndrome have been linked to alterations in the vascular system, including increased arterial stiffness and impaired endothelial function."



"Our findings may indicate improved glucocorticoid metabolism induced by oral magnesium supplementation, suggesting a potential mechanism by which increased dietary magnesium intake lowers cardiovascular disease risk."



"Our results provide a basis to further investigate effects of oral magnesium supplementation on cardiovascular risk and underlying mechanisms."



Source:
Clin Endocrinol (Oxf). 2020 Oct 8. doi: 10.1111/cen.14350. Online ahead of print.

@Amazoniac
@Mito
 

GenericName86

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Joined
Jun 30, 2018
Messages
195
Is there any merit to, depending on how deficient you are, that supplementing with magnesium can make you feel a bit worse to begin with? I've read some people report this and the answer given is that since mag is involved in so many enzyme processes that if you're quite deficient then taking mag and jump starting all those enzyme actions can perhaps cause you to feel a bit off at first.
 

LeeLemonoil

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Joined
Sep 24, 2016
Messages
2,306
If you are trly deficient with something that crucial to many proceedings then yes. Your organsims is a system that organises processes so effctively - it manages shortage sby compensating with unfeasible mechanisms, complex rearrangements. If you supply the better material to fall bac to, things have to be reorganized, get messed up initially.
It is no bagatelle. Energy, structure, reserves and commands, everything gets restructured, reorganizes, reassigned.
 

dukesbobby777

Member
Joined
Sep 22, 2020
Messages
166
Is there any merit to, depending on how deficient you are, that supplementing with magnesium can make you feel a bit worse to begin with? I've read some people report this and the answer given is that since mag is involved in so many enzyme processes that if you're quite deficient then taking mag and jump starting all those enzyme actions can perhaps cause you to feel a bit off at first.

It’s also an NMDA antagonist (albeit weaker than pharmaceutical ones), so initial acute effects can be somewhat dulling.
 
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