learnedhelpless
Member
So on top of SSRI's being serotonin antagonists, glucocorticoid antagonists and promoters of neurosteroids, they increase dopamine and NAD in the brain.
Once you recognise, the false , mechanism of the SSRI drugs (serotonin), you will soon realise, that despite nearly a century's worth of research, pharmaceutical companies cannot make a drug that is successful from serotonin alone, as in the end, as nature intended it for to be (despite what the universities want it to be), it is a stress promoter, released in stress.
Buspirone enhances duloxetine- and fluoxetine-induced increases in dialysate levels of dopamine and noradrenaline, but not serotonin, in the frontal cortex of freely moving rats
As shown in Fig. 1, buspirone and duloxetine alone increased DA levels in the FCX in comparison with vehicle-treated rats (100 and 65%, respectively)... Similarly, fluoxetine increased cortical DA levels (60%; Fig. 2), and in the presence of buspirone, fluoxetine induced an (at least) additive increase in DA levels (240%; Fig. 2). Dialysate levels of NAD were increased by both buspirone and duloxetine (160 and 400%, respectively; Fig. i) as well as by fluoxetine (90%; Fig. 2)
Once you recognise, the false , mechanism of the SSRI drugs (serotonin), you will soon realise, that despite nearly a century's worth of research, pharmaceutical companies cannot make a drug that is successful from serotonin alone, as in the end, as nature intended it for to be (despite what the universities want it to be), it is a stress promoter, released in stress.
Buspirone enhances duloxetine- and fluoxetine-induced increases in dialysate levels of dopamine and noradrenaline, but not serotonin, in the frontal cortex of freely moving rats
As shown in Fig. 1, buspirone and duloxetine alone increased DA levels in the FCX in comparison with vehicle-treated rats (100 and 65%, respectively)... Similarly, fluoxetine increased cortical DA levels (60%; Fig. 2), and in the presence of buspirone, fluoxetine induced an (at least) additive increase in DA levels (240%; Fig. 2). Dialysate levels of NAD were increased by both buspirone and duloxetine (160 and 400%, respectively; Fig. i) as well as by fluoxetine (90%; Fig. 2)