Serotonin Production In Adipose Tissue A Possible Target Of Obesity Drugs In The Future

[michael94]

In
general, receptor-specific activation or inhibition is thought to be
a better strategy for drug development. However, serotonin
plays different roles in different tissues by acting through different
receptors. Thus, inhibition of serotonin synthesis in adipose
tissue is a potentially beneficial strategy for anti-obesity treatment.
This strategy increases insulin sensitivity by simultaneously
decreasing lipogenesis and increasing adaptive thermogenesis.

https://l.facebook.com/l.php?u=http...doi=10.14348%2Fmolcells.2015.0258&h=LAQEE-Yae

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