OK so after an interesting niacin experiment (https://raypeatforum.com/community/threads/amazing-workout-experience-with-niacin) I started doing more reading and I came across something that doesn't seem to add up. It seems to me, from reading posts here and other places, that Niacin and Niacinamide act very differently with opposite lipolysis effects.
Niacin: triggers lipolysis, i.e. breaks down existing fat cells in the body and liberates their contents into the bloodstream. Example source: Niacin, Exercise, and Sauna: Detoxification Program for You
"The niacin regimen simply happens to mobilize fat and toxins faster using these artificial approaches. In the schematic diagram lipolysis of fat and toxin below showing when lipolysis can occur, even sleep will lead to lipolysis and weight loss, and of course toxic release, along with the use of agents like Niacin and agents like ephedra."
Niacinamide: inhibits lipolysis, i.e. stops the body from breaking down fat for fuel and so increases your need for sugar. Example source: Ray Peat, PhD Quotes on Therapeutic Effects of Niacinamide – Functional Performance Systems (FPS)
"Niacinamide, by reducing lipolysis, would be another antiinflammatory agent that could help to interrupt the degenerative processes initiated by exposure to radiation."
But they're both Vitamin B3 I thought! But if what I'm quoting above is true, then they are acting very differently. For example people use Niacin for detoxing with e.g. exercise and sauna sweating to get the bad stuff out, after acute release into the bloodstream. But it seems the Peat-approach is to use niacinamide to prevent fat being broken down at all so that the bad stuff inside the fat cells don't enter the blood stream at all.
About 6 months ago I stopped taking niacinamide because I noticed anecdotally that I was unable to lose weight (fat) while taking it. I think weight loss necessarily means liberating what's in the fat cells and therefore having potentially bad stuff enter your blood stream. Maybe this explains the primary stressfulness of modern weight loss (especially if they end up rebounding, just putting the weight back on with crappy PUFA, then re-libering it in their blood via yo-yo crash dieting, etc).
So then my questions are just,
1) Is this summary correct, the two forms of vitamin B3 have opposite lipolysis actions?
2) Does this imply that niacinamide is unhelpful for losing fat?
Thanks
Niacin: triggers lipolysis, i.e. breaks down existing fat cells in the body and liberates their contents into the bloodstream. Example source: Niacin, Exercise, and Sauna: Detoxification Program for You
"The niacin regimen simply happens to mobilize fat and toxins faster using these artificial approaches. In the schematic diagram lipolysis of fat and toxin below showing when lipolysis can occur, even sleep will lead to lipolysis and weight loss, and of course toxic release, along with the use of agents like Niacin and agents like ephedra."
Niacinamide: inhibits lipolysis, i.e. stops the body from breaking down fat for fuel and so increases your need for sugar. Example source: Ray Peat, PhD Quotes on Therapeutic Effects of Niacinamide – Functional Performance Systems (FPS)
"Niacinamide, by reducing lipolysis, would be another antiinflammatory agent that could help to interrupt the degenerative processes initiated by exposure to radiation."
But they're both Vitamin B3 I thought! But if what I'm quoting above is true, then they are acting very differently. For example people use Niacin for detoxing with e.g. exercise and sauna sweating to get the bad stuff out, after acute release into the bloodstream. But it seems the Peat-approach is to use niacinamide to prevent fat being broken down at all so that the bad stuff inside the fat cells don't enter the blood stream at all.
About 6 months ago I stopped taking niacinamide because I noticed anecdotally that I was unable to lose weight (fat) while taking it. I think weight loss necessarily means liberating what's in the fat cells and therefore having potentially bad stuff enter your blood stream. Maybe this explains the primary stressfulness of modern weight loss (especially if they end up rebounding, just putting the weight back on with crappy PUFA, then re-libering it in their blood via yo-yo crash dieting, etc).
So then my questions are just,
1) Is this summary correct, the two forms of vitamin B3 have opposite lipolysis actions?
2) Does this imply that niacinamide is unhelpful for losing fat?
Thanks