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Mitochondrial debris (from stress/injury) causes "autoimmune" disease
- Thread starter haidut
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Yes. A few times, maybe I will give it one more try@DonLore have you tried thiamine?
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Trehalose Sugar is very good for healthy cellular Homeostasis.
“Trehalose works by encouraging the healthy function of molecules known as chaperones. Molecular chaperones work to insure that the proteins inside our cells 'fold' together to ensure proper function of becoming an enzyme, or a hormone, etc.
(Unfolded proteins may trigger a cell-wide stress reaction resulting in a stress response that accelerates the cells aging process.)
Trehalose chaperones move in an attempt to "re-fold" the protein properly.”
“Trehalose treatment suppresses inflammation, oxidative stress, and vasospasm induced by experimental subarachnoid hemorrhage”
“Trehalose inhibits inflammatory cytokine production by protecting IκB-α reduction in mouse peritoneal macrophages”
Trehalose treatment suppresses inflammation, oxidative stress, and vasospasm induced by experimental subarachnoid hemorrhage
“Trehalose works by encouraging the healthy function of molecules known as chaperones. Molecular chaperones work to insure that the proteins inside our cells 'fold' together to ensure proper function of becoming an enzyme, or a hormone, etc.
(Unfolded proteins may trigger a cell-wide stress reaction resulting in a stress response that accelerates the cells aging process.)
Trehalose chaperones move in an attempt to "re-fold" the protein properly.”
“Trehalose treatment suppresses inflammation, oxidative stress, and vasospasm induced by experimental subarachnoid hemorrhage”
“Trehalose inhibits inflammatory cytokine production by protecting IκB-α reduction in mouse peritoneal macrophages”
Trehalose treatment suppresses inflammation, oxidative stress, and vasospasm induced by experimental subarachnoid hemorrhage
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I've never heard of this sugar before. In the study you posted, the rats were injected with trehalose. It looks like humans consuming the sugar would simply convert it into glucose, like most carbohydrates.
Short of injecting this, using it as an eye drop or learning how to block trehalase (who knows if this would be harmful in other ways), there's probably little utility in consuming this sugar.
examine.com
"Unfortunately, not only is trehalose initially poorly absorbed from the intestines but within the intestinal wall there is an enzyme (trehalase) which can rapidly degrade trehalose into glucose. For the trehalose that bypasses this enzyme and gets absorbed, the threhalase present in the liver and the blood appears to finalize the digestion leaving little to no trehalose able to reach a cell and exert its therapeutic effects.
The only way to preserve the effects of trehalose is to avoid oral ingestion by applying the compound topically leading to the promise of trehalose in protecting cellular function being exclusive to the skin, eyes, and hair. It has already shown therapeutic promise for the treatment of dry eye symptoms when used as eye drops, with a potency greater than commercially available products."
Short of injecting this, using it as an eye drop or learning how to block trehalase (who knows if this would be harmful in other ways), there's probably little utility in consuming this sugar.
Trehalose benefits, dosage, and side effects
Trehalose: The latest and most important research. Expert analysis and supporting evidence for practical effects, potential risks, and more.
"Unfortunately, not only is trehalose initially poorly absorbed from the intestines but within the intestinal wall there is an enzyme (trehalase) which can rapidly degrade trehalose into glucose. For the trehalose that bypasses this enzyme and gets absorbed, the threhalase present in the liver and the blood appears to finalize the digestion leaving little to no trehalose able to reach a cell and exert its therapeutic effects.
The only way to preserve the effects of trehalose is to avoid oral ingestion by applying the compound topically leading to the promise of trehalose in protecting cellular function being exclusive to the skin, eyes, and hair. It has already shown therapeutic promise for the treatment of dry eye symptoms when used as eye drops, with a potency greater than commercially available products."
I feel good using it, 5g in morning and 5g early evening.
“Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein”
Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein - PubMed
“In the last 20 years, trehalose has been found to be useful for the prevention of a number of common health problems, including osteoporosis [3], metabolic syndrome [4, 5], and Alzheimer’s disease [6]. With relevance to metabolic syndrome”
Daily consumption of one teaspoon of trehalose can help maintain glucose homeostasis: a double-blind, randomized controlled trial conducted in healthy volunteers - Nutrition Journal
“Amazingly, trehalose has been revealed as an attractive candidate to prevent and modify the progression of Parkinson’s disease”
“Interestingly, trehalose may have antidepressant-like properties as well as anti-hepatic-steatosis properties.”
Metabolic Associated Fatty Liver Disease as a Risk Factor for the Development of Central Nervous System Disorders
“Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein”
Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein - PubMed
“In the last 20 years, trehalose has been found to be useful for the prevention of a number of common health problems, including osteoporosis [3], metabolic syndrome [4, 5], and Alzheimer’s disease [6]. With relevance to metabolic syndrome”
Daily consumption of one teaspoon of trehalose can help maintain glucose homeostasis: a double-blind, randomized controlled trial conducted in healthy volunteers - Nutrition Journal
“Amazingly, trehalose has been revealed as an attractive candidate to prevent and modify the progression of Parkinson’s disease”
“Interestingly, trehalose may have antidepressant-like properties as well as anti-hepatic-steatosis properties.”
Metabolic Associated Fatty Liver Disease as a Risk Factor for the Development of Central Nervous System Disorders
EMF Mitigation - Flush Niacin - Big 5 Minerals
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