Are you sure about the anticholinergic effect?
Hydroxyzine has also been shown to act as an antagonist of the serotonin 5-HT2A receptor, the dopamine D2 receptor, and the α1-adrenergic receptor. The weak anti-serotonergic effects of hydroxyzine make it useful as an anxiolytic, as other antihistamines without such properties have not been found to be effective in the treatment of anxiety.
I didn't notice much anticholinergic sides, dry mouth etc., maybe the endotoxin (which is known to do) slowed or stopped peristalsis? This would mean you were absorbing a lot of endotoxin aka ivermectin was clearing you up. It would be an idea to pulse with AC + coconut oil or pregnelenone/progesterone to suck up the free endotoxin. Also 10k Vitamin A (somewhere in the vitamin A posts here in the forum) enhances endotoxin clearance. I noticed some "raised" estrogen with more "intestinal cleanup" aka endotoxin exposure too, so if I notice that, I take countermeasures as low starch, champignon mushrooms, ac, camphosal etc.,
as a male I couldn't speak about or experience PMS (luckily), so the only thing pointing to that are maybe the cyclical migraines.
If the combo of ivermectin and hydroxyzine is working well, a raised endotoxin level would be logical as Toxoplasma like organisms are gram-negative and if killed release a lot LPS.
Is Ivermectin free to buy in Bulgaria? If yes import would be easy as it is EU-EU country without special inspection rules customs wise.
Hydroxyzine
Primer
Hydroxyzine is a first-generation antihistamine (and anticholingeric) with a variety of uses and indications, including uses as an anxiolytic.Mechanism of Action
Hydroxyzine's predominant mechanism of action is as a potent and selective histamine (H1) receptor inverse agonist. This action is responsible for its antihistamine and sedative effects. Unlike other first-generation antihistamines like diphenhydramine (tradename: Benadryl), hydroxyzine has very low affinity for the muscarinic (acetylcholine) receptors. Therefore it is not a muscarinic receptor antagonist, which means it has very little anticholinergic side effects.Hydroxyzine has also been shown to act as an antagonist of the serotonin 5-HT2A receptor, the dopamine D2 receptor, and the α1-adrenergic receptor. The weak anti-serotonergic effects of hydroxyzine make it useful as an anxiolytic, as other antihistamines without such properties have not been found to be effective in the treatment of anxiety.
Hydroxyzine
Hydroxyzine Primer Hydroxyzine is a first-generation antihistamine (and anticholingeric) with a variety of uses and indications, including uses as an anxiolytic. Mechanism of Action Hydroxyzine's predominant mechanism of action is as a potent and selective histamine (H1) receptor inverse...
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I didn't notice much anticholinergic sides, dry mouth etc., maybe the endotoxin (which is known to do) slowed or stopped peristalsis? This would mean you were absorbing a lot of endotoxin aka ivermectin was clearing you up. It would be an idea to pulse with AC + coconut oil or pregnelenone/progesterone to suck up the free endotoxin. Also 10k Vitamin A (somewhere in the vitamin A posts here in the forum) enhances endotoxin clearance. I noticed some "raised" estrogen with more "intestinal cleanup" aka endotoxin exposure too, so if I notice that, I take countermeasures as low starch, champignon mushrooms, ac, camphosal etc.,
as a male I couldn't speak about or experience PMS (luckily), so the only thing pointing to that are maybe the cyclical migraines.
If the combo of ivermectin and hydroxyzine is working well, a raised endotoxin level would be logical as Toxoplasma like organisms are gram-negative and if killed release a lot LPS.
Is Ivermectin free to buy in Bulgaria? If yes import would be easy as it is EU-EU country without special inspection rules customs wise.