SB4
Member
- Joined
- Sep 25, 2016
- Messages
- 288
Sorry there has been a misunderstanding somewhere. With a high carb meal BHB should decrease to almost zero, however if you add MCT oil you see an increase in BHB. Like you say, MCT goes to liver and is converted to BHB.Very interesting, thanks for replying.
Why wouldn't BHB levels increase with MCT oil? Isn't that the whole point of MCT oil? That medium chain triglycerides go directly to the liver and gets converted to BHB. Is PDH involved in producing BHB?
Have you ever tried a ketogenic diet btw? Have you tried BHB-salts?
PDH is not directly involved in BHB production. The point I was trying to make was that there maybe a problem with PDH in CFS. So if we can avoid this enzyme we would get less lactate buildup, energy problems, etc. PDH converts pyruvate to acetyl coa. If you already have a ton of acetyl coa from mct then pyruvate is encouraged to go down through PC to oxaloacetate. Even if it does end up producing lactate you cell will still be able to make energy from the TCA.
This doesn't happen with normal fats. Normal fats when eaten with carbs get put into fat cells via insulin leaving you with a build up of pyruvate, a faulty PDH, a lack of energy, and thus lactate generation to free up NAD+ for glycolysis.