FDA authorizes Pfizer COVID-19 pill for emergency use

[Mito]

“Federal officials said the pill, known as Paxlovid, will be a vital tool in treating people who test positive, develop symptoms and are at higher risk of a bad outcome, though they warned that quantity might be limited due to the complex chemistry involved in making the pills.”

Pfizer oral COVID-19 pill gets U.S. authorization for at-home use

The FDA cleared use of Pfizer’s Paxlovid pill, the first Covid-19 drug that newly infected patients can now take at home to stay out of the hospital.

ground.news

“Nirmatrelvir is an antiviral drug developed by Pfizer which acts as an orally active 3CL protease inhibitor.[2][3][4][5] In December 2021, the combination of nirmatrelvir with the CYP3A4 inhibitor ritonavir was given Emergency Use Authorization by the FDA for the treatment of COVID-19 in high-risk patients over the age of 12 under the brand name Paxlovid.[6][7]”

Nirmatrelvir - Wikipedia

en.wikipedia.org

 

[JudiBlueHen]

I have the CYP3A4 *22 allele - slow metabolizer of about 50% of pharmaceuticals. This leads to larger AUC and more side effects due to inability to metabolize properly so the metabolites cannot be eliminated at a normal rate. This new drug is a definite AVOID for me. Not that I would trust it in the first place.

OK from reading the links it looks like the liver enzyme inhibitor is used to slow the metabolism of the active ingredients, meaning it is metabolized by CYP3A4.. However, it will slow down the metabolism of ALL meds and foods that use CYP3A4, potentially messing with the levels of other pharmaceuticals on board in the individual.

Also the claim that it "cuts hospitalization and death by 89%" based on a trial of only 2,250 patients in a TWO month study? I thought the death rate untreated was lower than 1 in 2,250, so what does this number mean? This EUA crap needs to stop!

 

[Mito]

Also the claim that it "cuts hospitalization and death by 89%" based on a trial of only 2,250 patients in a TWO month study? I thought the death rate untreated was lower than 1 in 2,250, so what does this number mean? This EUA crap needs to stop!

But at least it can’t be legally mandated unlike a vaccine.

 

[Perry Staltic]

Ritonavir was used in combo with the anti-viral Lopinavir (Kaletra) during the early days of covid. It was responsible for causing serotonin syndrome in at least two patients that were on anti-depressants because it interfered with those drugs metabolism. Probably a lot more cases went undetected and therefore unreported, and were probably attributed to covid. This full study used to be available, but you can still plug the DOI into Sci-Hub: removing barriers in the way of science to view it.

Serotonin syndrome in two COVID-19 patients treated with lopinavir/ritonavir | Request PDF

Request PDF | On May 1, 2020, Miguel Mas Serrano and others published Serotonin syndrome in two COVID-19 patients treated with lopinavir/ritonavir | Find, read and cite all the research you need on ResearchGate

www.researchgate.net

More info on Paxlovid:

Horowitz: The indefensible approval of Pfizer and Merck drugs compared to the snubbing of ivermectin | Blaze Media

Later this week, the FDA plans to approve, as the first outpatient COVID drugs, therapeutics that are extremely dangerous and unproven, even as the agency goes to war against cheap, safe, and proven drugs with a track record of no serious adverse events. The approval is as shocking as it is...

www.theblaze.com

“Ritonavir is not without its side effects, which can include life-threatening liver inflammation, pancreatitis, and heart arrhythmias. It may also cause nausea, diarrhea, dizziness, confusion, high cholesterol, high blood sugar, stomach or intestinal bleeding, numb hands and feet, a skin rash, as well as countless other side effects.” The FDA has issued a black box warning for many serious contraindications with ritonavir.

 

[Perry Staltic]

.From Nature study above. Ivermectin crushed everything else. GC367 is the control

Identification of 3-chymotrypsin like protease (3CLPro) inhibitors as potential anti-SARS-CoV-2 agents - Communications Biology

Here, the authors identify potential drugs that target 3-chymotrypsin like protease (3CLpro), which is a pivotal protease for the replication of SARS-CoV-2. They found that off-target inhibitors such as ivermectin and micafungin inhibit 3CLpro enzyme activity, suggesting that these molecules...

www.nature.com

 

[minni]

Infracting Nuremberg codes is also against the law, yet they broke the law via Covid nursing homes and toxic vaxes. Also see the following vid. of medical atrocities at Tuskegee, Willowbrook etc. Given that, why would they not "emergency mandate" Pfizer/Merck pills, whether legal or not?

View: https://www.bitchute.com/video/MJqXlNHXPcUl/
And I bet the pills already contain tracking biochips to "ensure compliance". I.E. see the below vid. Is Bourla hinting something here?

Marcel D. : Albert Bourla, PDG de Pfizer, discute de la puce électronique

View Marcel D. : Albert Bourla, PDG de Pfizer, discute de la puce électronique on Odysee

odysee.com

 

[Lollipop2]

Well Paxlovid seems to be horrible and now approved for children:

Did Pfizer Know that Paxlovid will NOT Work in the Vaccinated?

Also: Paxlovid was NOT Tested on Children, but FDA Approved it for Kids Anyway

igorchudov.substack.com

 

[Mito]

Paxlovid works, the vaccines don't​

Paxlovid works, the vaccines don't

Heads Pfizer shareholders win, tails you lose

alexberenson.substack.com

Conclusion
Treatment with NMV-r in non-hospitalized vaccinated patients with Covid-19 was associated with a reduced likelihood of emergency room visits, hospitalization, or death. Complications and overall resource utilization were also decreased.

Oral Nirmatrelvir and Ritonavir in Non-hospitalized Vaccinated Patients with Covid-19

AbstractBackground. Treatment of coronavirus disease-2019 (Covid-19) with nirmatrelvir plus ritonavir (NMV-r) in high-risk non-hospitalized unvaccinated patient

academic.oup.com

 

[Mito]

Pfizer COVID pill showed no benefit in adults under 65, study finds​

“Pfizer’s COVID-19 pill appears to provide little or no benefit for adults under 65 while still reducing the risk of hospitalization and death for high-risk seniors, according to a large study published Wednesday.”

Pfizer COVID pill showed no benefit in adults under 65, study finds

Paxlovid, Pfizer’s COVID-19 pill, appears to provide little or no benefit for adults 40 to 65, according to a new study.

www.latimes.com