endotoxin

  1. Mauritio

    Serotonin Causes Obesity, Diabetes, Fibrosis,liver Damage ,increases Endotoxin And NO

    Inspired by this thread Serotonin/endotoxin/PUFA As Primary Causes Of Depression And Diabetes; Can Be Easily Blocked I was reading a few more recent studies on the detrimental effect of serotonin on ones health. It seems clear that by now it is known in medicine, that blocking it is highly...
    • Mauritio
    • Thread
    • diabetes endotoxin fibrosis nitric oxide no obesity serotonin tlr4 tph tph inhibitor
    • Replies: 7
    • Forum: Scientific Studies
  2. haidut

    Emulsifiers Found In Most Commercial Foods Cause Brain Tumors, Hemorrhage, And Stroke

    A really interesting study that demonstrates how emulsifiers considered "benign" by the FDA/USDA and present in virtually all commercial food can actually cause quite a bit of damage to health. The study demonstrates that even a low-dose of a common commercial emulsifier Polysorbate 80 (P80)...
    • haidut
    • Thread
    • bacteria brain emulsifier endotoxin gut barrier hemorrhage lps stroke tlr4 translocation tumor
    • Replies: 18
    • Forum: Scientific Studies
  3. Mauritio

    Taurine Effective Against Endotoxin/ Liver Damage

    Another win for the super amino acid taurin. This study found out that a human dose of 2500mg was enough to antagonise the effect of endotoxin on the liver . Taurine alleviates lipopolysaccharide‑induced liver injury by anti‑inflammation and antioxidants in rats "The results from the present...
  4. haidut

    Endotoxin Has A G.E.L.D.I.N.G Effect, Causes Obesity And Hypogonadism

    A very interesting study proposing that the decline in gonadal function seen in obese/diabetic men is due to chronically elevated endotoxin levels in such people. The study calls this phenomenon (G)ut (E)dotoxin (L)eading to a (D)ecline (I)n (G)onadal function (GELDING) due to the remarkable...
    • haidut
    • Thread
    • castration diet endotoxin gelding high-fat hypogonadism inflammation leydig lps obesity tlr tlr4
    • Replies: 34
    • Forum: Scientific Studies
  5. haidut

    CamphoSal - Liquid Camphoric Acid + Salol

    As many readers know, Peat has written extensively on the benefits of antibiotics and on keeping the GI tract as free of bacteria as possible. Bacterial overgrowth in the colon alone is already a problem due to the production of endotoxin, but in hypothyroid people this bacterial overgrowth can...
    • haidut
    • Thread
    • antibiotic antiseptic camphoric acid camphosal digestion disinfectant dysbiosis endotoxin fermentation gut flora inflammation intestine lps microbiome phenyl salicylate salol sibo
    • Replies: 440
    • Forum: IdeaLabs
  6. haidut

    Supplementation With (long Chain) Saturated Fats Protects Liver From Alcohol

    As many of my readers already know, there are a number of human studies, going back to at least the 1960s, demonstrating that supplementation with saturated fats (SFA) protects the liver from damage induced by alcohol. I fact, supplementation with SFA not only prevents alcohol-induced liver...
    • haidut
    • Thread
    • alcohol damage dysbiosis dysfunction endotoxin ethanol fibrosis lcsfa liver lps protective reverse saturated fat sfa sibo tlr4 treatment
    • Replies: 1
    • Forum: Scientific Studies
  7. haidut

    Allopregnanolone As A Treatment Of Alzheimer Disease (AD)

    It looks like the recent FDA approval of allopregnanolone (ALLO) for postpartum depression may open the floodgates to ton of new research with this steroid, as well as with its reliable precursors such as pregnenolone and progesterone. I posted several studies in the past demonstrating that...
    • haidut
    • Thread
    • ad allo allopregnanolone alzheimer's endotoxin energy inflammation lps metabolism pregnenolone progesterone tlr tlr4 treatment
    • Replies: 0
    • Forum: Scientific Studies
  8. haidut

    Chronic Nerve Pain May Be Caused By Endotoxin, Commercial Food, And Pharma Drugs

    I posted a few threads last year demonstrating that some cases of chronic nerve pain may be caused by a side effects of opioids - activation of TLR4. However, that study only looked at why certain patients using opioids for severe pain go on to develop chronic pain of phantom origin. As such...
    • haidut
    • Thread
    • commercial food endotoxin iatrogenic inflammation lps lysozyme nerve pain neuropathy pharmaceutical drugs tlr tlr4
    • Replies: 5
    • Forum: Scientific Studies
  9. haidut

    Inhibiting Fatty Acid Synthesis (FAS) Dramatically Improves Sepsis Survival Rate

    Yet another study that points the finger straight at fat as a key factor in one of the most common causes of inpatient hospital mortality - sepsis. Sepsis is currently considered to be a condition of infectious (bacterial) etiology, driven by endotoxin. However, in light of the new findings it...
    • haidut
    • Thread
    • endotoxin energy fao fas fasn fatty acid oxidation fatty acid synthase infection inhibit inhibitor randle cycle sepsis tlr tlr4
    • Replies: 6
    • Forum: Scientific Studies
  10. haidut

    Progesterone May Bind And Deactivate Endotoxin (LPS) Directly

    I made a few posts recently discussing the blocking effects of pregnenolone on TLR4 and TLR family receptors in general, and the reduction of systemic inflammation stemming from this blockade/regulation...
    • haidut
    • Thread
    • bind block covalent deactivate endotoxin histamine inflammation lps pregnenolone progesterone react serotonin tlr tlr4
    • Replies: 15
    • Forum: Scientific Studies
  11. haidut

    Niacinamide May Improve Symptoms Of ALS

    Just over a week ago I posted a thread on ALS being linked to increased fatty acid oxidation (FAO) and as such a decreased glucose availability/oxidation. ALS Tied To Increased Fat Oxidation (FAO), Increasing Glucose May Treat It Now, the study below further corroborates this FAO-disease...
    • haidut
    • Thread
    • als endotoxin fao lps microbiome niacinamide vitamin b3
    • Replies: 9
    • Forum: Scientific Studies
  12. P

    Prebiotic And Anti Endotoxin Effects Of Dietary Calcium

    Calcium supplementation modulates gut microbiota in a prebiotic manner in dietary obese mice. - PubMed - NCBI Could the beneficial effects of dietary calcium on obesity and diabetes control be mediated by changes in intestinal microbiota and integrity? - PubMed - NCBI
  13. haidut

    Endotoxin (LPS) Linked To Lower Survival In Cancer

    Another study about endotoxin, this time linking higher sensitivity to endotoxin to lower survival chance for people with lymphoma. While the study below looked at only one cancer, there are multiple studies with other cancer that have found similar link. Endotoxin and cancer go hand in hand...
    • haidut
    • Thread
    • cancer cause endotoxin exacerbate lps lymphoma mortality tlr tlr4
    • Replies: 2
    • Forum: Scientific Studies
  14. haidut

    Blocking Endotoxin (LPS) May Reverse/cure Diabetes Type I

    Yet another study demonstrating the key role of endotoxin in the pathology of perhaps the most widespread chronic disease - diabetes. The study below discovered that the proliferation of the insulin-producing beta-cells in the pancreas is controlled almost entirely by the TLR4/TLR2 receptor...
    • haidut
    • Thread
    • beta-cells cause diabetes endotoxin inflammation insulin lps pancreas tlr tlr2 tlr4
    • Replies: 5
    • Forum: Scientific Studies
  15. haidut

    Endotoxin (LPS) May Cause Depression / Anhedonia

    As many readers know, anhedonia is one of the most pernicious aspects of clinical depression. It is present in other mental health conditions but is most pronounced and severe in clinical unipolar depression. It is also especially resistant to treatment and many doctors simply accept it as...
    • haidut
    • Thread
    • anhedonia cause depression endotoxin inflammation lps tlr tlr4
    • Replies: 31
    • Forum: Scientific Studies
  16. haidut

    Endotoxin (LPS) May Be A Major Cause Of Preterm Births

    As many readers have probably heard, rates of preterm births due to a variety of maternal conditions including (pre)eclampsia has been steadily increasing since the 1980s. The official version is that the cause is unknown despite older studies proving definitively that progesterone deficiency...
    • haidut
    • Thread
    • cause drive endotoxin exacerbate il-10 il-6 inflammation lps preemie pregnancy preterm birth tlr4
    • Replies: 0
    • Forum: Scientific Studies
  17. haidut

    All Gut Bacteria Dangerous, Its Endotoxin Drives Liver Cancer; Antibiotics Cure

    As Peat has written many times, there is truly no such thing as “beneficial” gut bacteria as long as they are capable of producing endotoxin (LPS). And since most bacterial species known to colonize the gut can produce LPS when exposed to undigested food or mechanical stimulation (stretching or...
    • haidut
    • Thread
    • antibiotics bacteria cancer colon cure endotoxin gut hcc hepatocellular carcinoma inflammation liver lps microbiome probiotics tlr4
    • Replies: 147
    • Forum: Scientific Studies
  18. haidut

    Damaged Mitochondria And Endotoxin (LPS) Drive Chronic Inflammation

    Chronic, low-grade inflammation has now been recognized as the main cause behind a number of chronic degenerative conditions including CVD, diabetes, cancer, Alzheimer, Parkinson, etc. Mainstream medicine claims that the cause of this chronic low-grade inflammatory reaction is unknown, despite...
    • haidut
    • Thread
    • choline chronic damage endotoxin inflammation lps mitochondria mitophagy stress tlr4
    • Replies: 5
    • Forum: Scientific Studies
  19. haidut

    A Lab Test For Endotoxin Exposure, And Its Role In HIV/AIDS

    While I was researching some other topics related to the article on statins and TLR4 that I posted last week, I stumbled upon a biomarker called "soluble CD14" or sCD14 for short. CD14 - Wikipedia As it turns out, sCD14 is a biomarker for systemic endotoxin load. The importance of soluble CD14...
    • haidut
    • Thread
    • biomarker cd14 endotoxin exposure inflammation load lps scd14 soluble cd14 tlr4
    • Replies: 9
    • Forum: Scientific Studies
  20. haidut

    Endotoxin Causes Cachexia In Cancer; How Statin Drugs Really Work

    The title of the post is a bit strange but it is pretty much what the study below found. Just like the SSRI drugs, the mechanism of action of statins is (officially) not really known. The official version for the antidepressant effects of SSRI drugs was that they increase intracellular levels of...
    • haidut
    • Thread
    • atorvastatin block brown fat cachexia cancer endotoxin lipitor lps prevent statin statins tlr4 tumor wasting
    • Replies: 8
    • Forum: Scientific Studies
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