Emulsifiers Found In Most Commercial Foods Cause Brain Tumors, Hemorrhage, And Stroke

haidut

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A really interesting study that demonstrates how emulsifiers considered "benign" by the FDA/USDA and present in virtually all commercial food can actually cause quite a bit of damage to health. The study demonstrates that even a low-dose of a common commercial emulsifier Polysorbate 80 (P80) damages the mucosal barrier of the gut and increases both endotoxin (LPS) and actual bacterial translocation to the brain. Once there, LPS activates the "endotoxin" receptor TLR4 and that leads to the formation of tumors known as cerebral cavernoma (CMM). This is yet another study that links endotoxin/LPS to tumor formation. I made a number of posts a few months ago demonstrating that liver, pancreatic, colon, lung, and even esophageal cancers are also linked to bacterial and LPS translocation from the gut to the respective organ/tissue where the tumor formed. However, those studies did not go as far as stating that the endotoxin/LPS/bacteria were the direct cause of the cancer/tumor, while this new study does. Aside from the polysorbates, other emulsifiers known to disrupt the mucosal barrier include carrageenan (which is actually a known carcinogen) as well as various gums such as locust bean, acacia gum, carob bean gum, etc. These emulsifiers are authorized for use even in products certified as organic by USDA, but their levels in organic foods are subject to tighter restrictions, while their levels in non-organic foods are largely unregulated. A few recent studies discovered that products from fast food chains such as Burger King, McDonalds, Wendy's, Popeye's, etc contain the highest amount of emulsifiers of all commercial foods tested. I suspect that it is the presence of those (indirectly) carcinogenic additives that allow fast food items to survive more than 20 years without ANY decay, as the bacteria that normally degrades/metabolizes food left out in the open is also quite vulnerable to those toxic additives. The fact that many hospitals serve fast food from these chains to hospitalized patients, often people with GI disorders/surgeries/procedures, makes me cringe...

Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation | Science Translational Medicine
A new mechanism identifies a gut-brain axis in cerebral cavernous malformation

"...For many years, scientists have studied the link between gut microbiota and diseases such as dementia, autism, Parkinson’s, diabetes, obesity or colitis, proving that each disease has a specific gut microbiota profile. Studies have also focused on the gut-brain axis, in which bacterial lipopolysaccharides (LPS) translocate to the brain through circulating blood, while gut microbiota also generates metabolites that affect brain function and the immune system. However, we are yet to identify the specific mechanisms, molecules, and genes that cause a disease: a finding that would allow us to develop appropriate therapies. A new publication from Alan T. Tang of the University of Pennsylvania focuses on explaining the relationship between gut microbiota and cerebral cavernous malformation (CCM), which is a neurological disease that leads to hemorrhagic stroke and seizure."

"...In a third objective, Tang decided to investigate the impact of disrupted gut microbiota and epithelium cells damage induced by dextran sulfate sodium (DSS). In mice that develop CCM due to endothlial cell specific deletion of Krit1, only 50% survived DSS treatment, and survivors showed a twofold increase in CCM volume compared to vehicle treated littermate controls. Thus, chemical disruption of the gut epithelial barrier exacerbated CCM disease."

"...Researchers wanted to prove their hypotheses with non-invasive treatment. As it is known that emulsifiers found in processed foods promote colitis by degrading the mucosal barrier, they treated a PDCD10-deleted mouse with a low quantity of P80 (emulsifier) and noted a low but significant increase in mucosal barrier lesions. The main goal of this research was to identify the mechanism by which PDCD10 deletion in individuals is responsible for increased bacterial translocation and CMM symptoms."
 
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ddjd

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Aside from the polysorbates, other emulsifiers known to disrupt the mucosal barrier include carrageenan (which is actually a known carcinogen) as well as various gums such as locust bean, acacia gum, carob bean gum, etc. These emulsifiers are authorized for use even in products certified as organic by USDA, but their levels in organic foods are subject to tighter restrictions, while their levels in non-organic foods are largely unregulated.
Why is acacia gum touted as a health product if it's so dangerous?
 

Grapelander

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Polyglycerol polyricinoleate (PGPR)

In 2013 Wikipedia:
“It is used by chocolate makers to reduce their costs of raw materials. Since 2006, commercial-grade candy bars, such as those made by Hersheys and Nestle, made an industry-wide switch to include PGPR as an ingredient – a possible indicator of a cost-saving measure by the commercial chocolate industry."

That comment (2022) is not in Wikipedia anymore - it just notes how it makes the chocolate easier to work with:
"E476, is an emulsifier made from glycerol and fatty acids (usually from castor bean, but also from soybean oil).
In chocolate, compound chocolate and similar coatings, PGPR is mainly used with another substance like lecithin to reduce viscosity."
 

joaquin

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What about "cellulose powder" used in Parmesan cheese?
 
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"...Here we report that, in mice, relatively low concentrations of two commonly used emulsifiers, namely carboxymethylcellulose and polysorbate-80, induced low-grade inflammation and obesity/metabolic syndrome in wild-type hosts and promoted robust colitis in mice predisposed to this disorder."

Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome. - PubMed - NCBI
Polysorbate-80 is found in some hypertension medications. :shock:
 

mostlylurking

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A really interesting study that demonstrates how emulsifiers considered "benign" by the FDA/USDA and present in virtually all commercial food can actually cause quite a bit of damage to health. The study demonstrates that even a low-dose of a common commercial emulsifier Polysorbate 80 (P80) damages the mucosal barrier of the gut and increases both endotoxin (LPS) and actual bacterial translocation to the brain. Once there, LPS activates the "endotoxin" receptor TLR4 and that leads to the formation of tumors known as cerebral cavernoma (CMM). This is yet another study that links endotoxin/LPS to tumor formation. I made a number of posts a few months ago demonstrating that liver, pancreatic, colon, lung, and even esophageal cancers are also linked to bacterial and LPS translocation from the gut to the respective organ/tissue where the tumor formed. However, those studies did not go as far as stating that the endotoxin/LPS/bacteria were the direct cause of the cancer/tumor, while this new study does. Aside from the polysorbates, other emulsifiers known to disrupt the mucosal barrier include carrageenan (which is actually a known carcinogen) as well as various gums such as locust bean, acacia gum, carob bean gum, etc. These emulsifiers are authorized for use even in products certified as organic by USDA, but their levels in organic foods are subject to tighter restrictions, while their levels in non-organic foods are largely unregulated. A few recent studies discovered that products from fast food chains such as Burger King, McDonalds, Wendy's, Popeye's, etc contain the highest amount of emulsifiers of all commercial foods tested. I suspect that it is the presence of those (indirectly) carcinogenic additives that allow fast food items to survive more than 20 years without ANY decay, as the bacteria that normally degrades/metabolizes food left out in the open is also quite vulnerable to those toxic additives. The fact that many hospitals serve fast food from these chains to hospitalized patients, often people with GI disorders/surgeries/procedures, makes me cringe...

Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation | Science Translational Medicine
A new mechanism identifies a gut-brain axis in cerebral cavernous malformation

"...For many years, scientists have studied the link between gut microbiota and diseases such as dementia, autism, Parkinson’s, diabetes, obesity or colitis, proving that each disease has a specific gut microbiota profile. Studies have also focused on the gut-brain axis, in which bacterial lipopolysaccharides (LPS) translocate to the brain through circulating blood, while gut microbiota also generates metabolites that affect brain function and the immune system. However, we are yet to identify the specific mechanisms, molecules, and genes that cause a disease: a finding that would allow us to develop appropriate therapies. A new publication from Alan T. Tang of the University of Pennsylvania focuses on explaining the relationship between gut microbiota and cerebral cavernous malformation (CCM), which is a neurological disease that leads to hemorrhagic stroke and seizure."

"...In a third objective, Tang decided to investigate the impact of disrupted gut microbiota and epithelium cells damage induced by dextran sulfate sodium (DSS). In mice that develop CCM due to endothlial cell specific deletion of Krit1, only 50% survived DSS treatment, and survivors showed a twofold increase in CCM volume compared to vehicle treated littermate controls. Thus, chemical disruption of the gut epithelial barrier exacerbated CCM disease."

"...Researchers wanted to prove their hypotheses with non-invasive treatment. As it is known that emulsifiers found in processed foods promote colitis by degrading the mucosal barrier, they treated a PDCD10-deleted mouse with a low quantity of P80 (emulsifier) and noted a low but significant increase in mucosal barrier lesions. The main goal of this research was to identify the mechanism by which PDCD10 deletion in individuals is responsible for increased bacterial translocation and CMM symptoms."

Multiple Vitamins for Infusion - Food and Drug Administration

solubilized in an aqueous medium with polysorbate 80, permitting intravenous administration of these vitamins. Contains no more than 475 mcg/L of aluminum (combined Vials 1 and 2). Indications and Usage INFUVITE ADULTis indicated as a daily multivitamin maintenance supplement for adults and children aged 11 and older receiving parenteral nutrition.
 

joaquin

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ddjd

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If it is all natural then its beneficial for man?
I don't think that's the point of the article. It's saying it's a natural product PLUS has antimicrobial and anti cancer properties
 

joaquin

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I don't think that's the point of the article. It's saying it's a natural product PLUS has antimicrobial and anti cancer properties
Some microbes may be beneficial?
 
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A really interesting study that demonstrates how emulsifiers considered "benign" by the FDA/USDA and present in virtually all commercial food can actually cause quite a bit of damage to health. The study demonstrates that even a low-dose of a common commercial emulsifier Polysorbate 80 (P80) damages the mucosal barrier of the gut and increases both endotoxin (LPS) and actual bacterial translocation to the brain. Once there, LPS activates the "endotoxin" receptor TLR4 and that leads to the formation of tumors known as cerebral cavernoma (CMM). This is yet another study that links endotoxin/LPS to tumor formation. I made a number of posts a few months ago demonstrating that liver, pancreatic, colon, lung, and even esophageal cancers are also linked to bacterial and LPS translocation from the gut to the respective organ/tissue where the tumor formed. However, those studies did not go as far as stating that the endotoxin/LPS/bacteria were the direct cause of the cancer/tumor, while this new study does. Aside from the polysorbates, other emulsifiers known to disrupt the mucosal barrier include carrageenan (which is actually a known carcinogen) as well as various gums such as locust bean, acacia gum, carob bean gum, etc. These emulsifiers are authorized for use even in products certified as organic by USDA, but their levels in organic foods are subject to tighter restrictions, while their levels in non-organic foods are largely unregulated. A few recent studies discovered that products from fast food chains such as Burger King, McDonalds, Wendy's, Popeye's, etc contain the highest amount of emulsifiers of all commercial foods tested. I suspect that it is the presence of those (indirectly) carcinogenic additives that allow fast food items to survive more than 20 years without ANY decay, as the bacteria that normally degrades/metabolizes food left out in the open is also quite vulnerable to those toxic additives. The fact that many hospitals serve fast food from these chains to hospitalized patients, often people with GI disorders/surgeries/procedures, makes me cringe...
I knew hospital food is bottom of the barrel, but I had no idea they stooped so low as to offer fast food! Nutrition and good health are obviously not a priority for them, because there is no money to be gotten from healthy people…

“In 1992, Truman agreed to a 25-year contract with McDonald's, at a time when the financial benefit of having a stable food service client in the hospital outweighed any potential health concerns.

But times have changed, and now other hospitals interested in replacing fast food with more healthful options may find it isn't as easy as it seems. In Ohio, the Cleveland Clinic tried in vain to terminate its contract early with McDonald's 10 years ago. At the time, the clinic's lead heart surgeon (and now hospital CEO), Delos Cosgove, proposed removing all fast food vendors.

The Pizza Hut did close. But McDonald's stayed and remains a tricky relationship for the hospital, which has since removed sugary beverages and trans fats from its campus offerings. "We're just going to live with it," Bill Barum, director of hospitality and retail services for the Cleveland Clinic, tells The Salt. "When the contract ends, we'll have the opportunity to re-examine the space.”
 

bookshelf

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I take a tsp of acacia powder daily for leaky gut. Is there a study showing it's harmful?
Did you ever find an answer to your question? I get that carageenan is proven to be bad but other gums seem to be benign or there's no hard information on them one way or another. Based off of the study cited, t seems like 'all gums are bad' is a sweeping statement and doesn't consider the up-sides (or at least them being generally regarded as safe). There are a lot of great products out there that have some gums in them and I wonder, if those (such as acacia gum) are still ok to use.
 

S.Holmes

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Did you ever find an answer to your question? I get that carageenan is proven to be bad but other gums seem to be benign or there's no hard information on them one way or another. Based off of the study cited, t seems like 'all gums are bad' is a sweeping statement and doesn't consider the up-sides (or at least them being generally regarded as safe). There are a lot of great products out there that have some gums in them and I wonder, if those (such as acacia gum) are still ok to use.
I haven't. I've put it on the back burner and trying some other things.
 

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