atp

  1. haidut

    Restoring oxidative metabolism has curative effects on cancer (leukemia)

    A great study, which directly demonstrates not only the OXPHOS deficiency characteristic of all "cancer" cells, but also proving that restoration of OXPHOS is highly therapeutic (and likely curative) for leukemia. Just as importantly, the study demonstrates that cancer cells have, in fact...
  2. haidut

    Infrared/red light applied to the skull can treat Alzheimer's/dementia...

    ...and improve cognition even in healthy people! The mechanism of action is the familiar effects of red/infrared light on stimulating mitochondrial function, and especially complex IV, while also decreasing chronic inflammation. The regimen was light exposure for 6min, twice a day, for 4 weeks...
  3. haidut

    Vitamin B1 and/or biotin may treat Huntington Disease (HD)

    As some of my own studies with cancer recently demonstrated, vitamins are no laughing matter when it comes to their ability to treat very serious conditions. This seems to be especially true in regards to the B vitamins, which are required co-factors for most of the metabolic reactions inside...
  4. haidut

    Both "long" COVID-19 and CFS are likely caused by hypometabolism

    A good study that examines the remarkable parallels between the so-called "long" COVID-19 (i.e. chronic display of symptoms associated with COVID-19) and the (in)famous chronic fatigue syndrome (CFS). Namely, increases inflammation, excessive glycolysis, suppressed mitochondrial function and...
  5. Hans

    Tired of feeling anxious and submissive? Here’s how to fix it

    It all comes down to energy production. How effectively your cells can produce energy. https://men-elite.com/2021/08/16/tired-of-feeling-anxious-and-submissive-heres-how-to-fix-it/ I'd also like to hear from you. What has worked great for you to optimize both your energy and reduce anxiety?
  6. haidut

    Muscle weakness / wasting linked to poor mitochondrial function

    A study that once again illustrates the central principle of bioenergetics - structure and function cannot be separated. They are interdependent at every level. In this specific case, the "structural" pathology is muscle weakness and wasting (sarcopenia, cachexia, etc). Most doctors, when...
  7. Hans

    PUFAs, cardiolipin, ATP production and obesity

    As we all know, PUFAs are a metabolic toxin. One of the mechanisms how a high fat diet promotes obesity and metabolic syndrome is by remodeling cardiolipin. Cardiolipin is a unique mitochondrial phospholipid that contains 4 fatty acids. Its main goal is to stabilize the complexes of the electron...
  8. Hans

    Fructose series part 1: fructose depletes ATP?

    Every heard that fructose might deplete ATP? That's one silly argument that I debunk here. https://men-elite.com/2021/02/18/fructose-series-part-1-fructose-depletes-atp/
  9. haidut

    Niacinamide may treat ALS by improving energetic state

    Another study sent to me by the Austrian collaborator. Once again, the energetic origin of "incurable" diseases like amyotrophic lateral sclerosis (ALS) is on full display. The study elucidates that ALL types of ALS are characterized by metabolic/energetic abnormalities and the metabolic...
  10. haidut

    Niacinamide may treat depression by improving energetic state

    A very interesting study, sent to me by a collaborator who lives in Austria. It demonstrated that depression is accompanied by increased SIRT1 activity (i.e. increased fatty acid oxidation), lower ATP levels and redox balance shifted towards reduction. The study demonstrated that animals without...
  11. S

    Starting Anti Glycolytic Kettlebell Training

    Using Pavel's The Quick and the Dead. Not too sure what to put in log here, so here goes: Age 53 Sex M Weight 248 Height 5'11" Waking temp: 98.2 - 98.8 Health and stats steadily improving over last 8 months of Peating. This type of trainingg is supposed to increase ATP and mitochondrial...
  12. haidut

    Restoring Metabolism Prevents / Reverses "permanent" Nerve Damage

    Yet another study demonstrating the crucial role cellular metabolism plays in pathological processes. While most of my posts deal with beneficial effects of improving OXPHOS on various chronic diseases, the study below demonstrates that the same may be true in acute pathologies such as traumatic...
  13. haidut

    Glucose Is Anabolic For Thymus, Opposes Catabolic Effects Of Cortisol

    As most of my readers know, cortisol is a highly catabolic steroid and one of the main agents (estrogen being another) responsible for thymus atrophy with age. These catabolic effects of cortisol can be blocked by progesterone, DHEA, pregnenolone, and even DHT (but not by testosterone). The...
  14. haidut

    Niacinamide May Restore Female Fertility In Old Age

    The mainstream medical dogma is that after the onset of menopause, female reproductive potential is essentially zero. I posted a thread recently that challenged that dogma and demonstrated that infertility is essentially an energetic dysfunction process and can be reversed with exposure to red...
  15. haidut

    Mitochondria (energy) As The Main Driver Of Health, Intelligence, And Aging

    We are finally starting to see Peat enter the mainstream and article like the one below are calling for a complete review of what we know about health and aging and how intelligence is tied to them. As the authors says, or actually borrows from Peat, there is solid evidence that mitochondrial...
  16. haidut

    Fertility Depends On Metabollism (ATP), Not Age

    As many of you know, there are 2 fundamental dogmas in reproductive medicine. One is that every woman is born with a fixed number of eggs and those cannot be replenished. The second one is that there is a biological fertility clock in every woman that inexorably ticks, and if the female does not...
  17. haidut

    Chronic Stress / Defeat Causes Mental Illness By Damaging Mitochondria

    Yet another study demonstrating that mental illness has little to do with genetics, and is likely entirely due to energetic deficiency caused by environmental stress. This energetic deficiency is caused by mitochondrial damage caused by said stress. Keeping lipolysis and/or PUFA intake low can...
  18. M

    Serotonin Injection Induces A Dramatic Fall In Brain ATP Levels

    This is a study from 1994 by Koren-Schwartzer et al. that is often cited often by Ray Peat. It shows that intraperitoneal serotonin injection (40 mg/kg) causes a dramatic fall in brain ATP levels (24% of normal level). What I don't understand is how the injected serotonin in the peritoneum can...
  19. haidut

    Liver Disease Is Caused By Low ATP Driven By Fat (PUFA) Oxidation

    I posted a study several months ago on the ability of inosine to prevent/reverse liver disease, and how liver damage caused by various toxins was due to lower ATP levels in the liver. Inosine, being both a metabolite and precursor of ATP, is able to restore ATP levels and as such to...
  20. haidut

    Morphostasis Theory Of Immunity Confirmed - Body Treats Heart Attack Like Viral Infection

    Peat has touched upon his views of the immune system in several articles, mostly related to autoimmune disease. In his view, the role of the immune system is not so much to "attack" foreign pathogens that threaten the organism, but is more akin to sanitation workers who clean up trash and other...
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