1. cs3000

    Iron is essential for ability of thyroid hormone to function

    Study highlighting the importance of having good iron levels for peat approach to health. in the peat realm sometimes there's a tilted view against iron as if it's on the same level as a PUFA or something to be avoided, so can be overlooked. (overload toxicity isn't good + trying to fix...
  2. Mauritio

    The performance enhancing effects of erythromycin

    This study looked at the performance enhancing effects of erythromycin and other anti-biotics in mice, with some pretty interesting results. Erythromycin was very effective at increasing the swimming time in mice. "After intragastric administration for 3consecutive days, erythromycin showed a...
  3. haidut

    Vitamin B1 (thiamine) may treat Amyotrophic Lateral Sclerosis (ALS)

    A human case study, corroborated by the literature review done by the authors, suggesting that yet another degenerative and invariably lethal condition may be nothing more than energetic deficiency in disguise. The literature review the authors performed revealed that ALS patients, as well as...
  4. cs3000

    Cerebral vitamin B5 deficiency (pantothenic acid) as a potentially reversible cause of neurodegeneration and dementia in Alzheimers HD PD [myelin] b5 plays a role in helping age related cognitive decline , used for myelin aka. the sheath around nerves that enables electrical signals to travel well , along with cellular ATP from oxidative phosphorylation Vitamin B5 (d-pantothenic...
  5. haidut

    Metabolic rate may determine personality type and disease risk

    Very interesting study that links mitochondrial density/number (and as such, the metabolic rate) with personality types. Namely, people with fewer mitochondrial (i.e. hypometabolic) tend to have high levels of neuroticism, with the latter causally linked to a higher risk of a number of serious...
  6. haidut

    Thiamine+biotin can treat Huntington Disease (HD), by restoring glucose metabolism

    Many carrot-salads ago, back in ancient pre-pandemic times, I posted a study on high-dose biotin (300mg daily) stopping the so-called primary-progressive multiple sclerosis (PPMS) - the most aggressive variant of this "autoimmune" illness. The proposed mechanism of action for the benefit seen in...
  7. haidut

    Niacinamide fully reverses endotoxemia and leaky gut (from ethanol)

    The study below is a true gem due to both its broadness of impact, as well as the ease and low-cost of the therapeutic intervention it studied. Chronic endotoxemia, a cause and a result of increased gut permeability (aka "leaky gut") is now known to be a major cause of virtually all chronic...
  8. A

    DHT + T3 + Creatine combo

    + pyrucet Explosive.
  9. haidut

    Niacinamide increases ATP/NAD, lower glucose/cortisol in humans

    A great new study demonstrating for the first time in a human experiment what hundreds of animal studies had suggested in the past. Namely, that niacinamide can serve as a reliable precursor to NAD+ and by raising the NAD/NADH ratio results in improved glucose metabolism and higher ATP levels...
  10. Sefton10

    Mitochondrial Calcium: Effects of Its Imbalance in Disease

    Mitochondrial Calcium: Effects of Its Imbalance in Disease
  11. A

    The heart cannot be the sole driver of blood circulation

    The circulation appears to be driven not only by the heart, but also by the vessels themselves. The fuel for this second driving mechanism lies in infrared energy, which emerges naturally from metabolic heat, as well as from external sources (solar energy)...
  12. Hans

    The ultimate macronutrient (and supplement) for longevity and health aging!

    New study talking about pyruvate, NAD, synolytics, etc. Lots of cool stuff. View:
  13. haidut

    Restoring oxidative metabolism has curative effects on cancer (leukemia)

    A great study, which directly demonstrates not only the OXPHOS deficiency characteristic of all "cancer" cells, but also proving that restoration of OXPHOS is highly therapeutic (and likely curative) for leukemia. Just as importantly, the study demonstrates that cancer cells have, in fact...
  14. haidut

    Infrared/red light applied to the skull can treat Alzheimer's/dementia...

    ...and improve cognition even in healthy people! The mechanism of action is the familiar effects of red/infrared light on stimulating mitochondrial function, and especially complex IV, while also decreasing chronic inflammation. The regimen was light exposure for 6min, twice a day, for 4 weeks...
  15. haidut

    Vitamin B1 and/or biotin may treat Huntington Disease (HD)

    As some of my own studies with cancer recently demonstrated, vitamins are no laughing matter when it comes to their ability to treat very serious conditions. This seems to be especially true in regards to the B vitamins, which are required co-factors for most of the metabolic reactions inside...
  16. haidut

    Both "long" COVID-19 and CFS are likely caused by hypometabolism

    A good study that examines the remarkable parallels between the so-called "long" COVID-19 (i.e. chronic display of symptoms associated with COVID-19) and the (in)famous chronic fatigue syndrome (CFS). Namely, increases inflammation, excessive glycolysis, suppressed mitochondrial function and...
  17. Hans

    Tired of feeling anxious and submissive? Here’s how to fix it

    It all comes down to energy production. How effectively your cells can produce energy. I'd also like to hear from you. What has worked great for you to optimize both your energy and reduce anxiety?
  18. haidut

    Muscle weakness / wasting linked to poor mitochondrial function

    A study that once again illustrates the central principle of bioenergetics - structure and function cannot be separated. They are interdependent at every level. In this specific case, the "structural" pathology is muscle weakness and wasting (sarcopenia, cachexia, etc). Most doctors, when...
  19. Hans

    PUFAs, cardiolipin, ATP production and obesity

    As we all know, PUFAs are a metabolic toxin. One of the mechanisms how a high fat diet promotes obesity and metabolic syndrome is by remodeling cardiolipin. Cardiolipin is a unique mitochondrial phospholipid that contains 4 fatty acids. Its main goal is to stabilize the complexes of the electron...
  20. Hans

    Fructose series part 1: fructose depletes ATP?

    Every heard that fructose might deplete ATP? That's one silly argument that I debunk here.