Ray has written about the benefits of dessicated thyroid and the dangers of pure T4. However, for the last several decades researchers like him have been consistently ignored by mainstream medicine and even the venerable Armour changed their formula to mimic better the effects of pure T4.
However, given the disastrous results of monotherapy over the last decade, mainstream medicine is starting to recognize the dangers of Synthroid (pure T4). According to this study, most patients (65%) not only benefit physiologically from switching to combined T4/T3 regimen but also do NOT want to go back to pure T4 after trying the combined regimen. The study also has some interesting discussion on how pure T4 can have anti-thyroid effects by conversion to rT3 and what is the optimal ratio of T4 to T3.
http://suppversity.blogspot.de/2012/08/ ... d-try.html
However, given the disastrous results of monotherapy over the last decade, mainstream medicine is starting to recognize the dangers of Synthroid (pure T4). According to this study, most patients (65%) not only benefit physiologically from switching to combined T4/T3 regimen but also do NOT want to go back to pure T4 after trying the combined regimen. The study also has some interesting discussion on how pure T4 can have anti-thyroid effects by conversion to rT3 and what is the optimal ratio of T4 to T3.
http://suppversity.blogspot.de/2012/08/ ... d-try.html