Self Amplifying mRNA "vaccine"

[Peatness]

VARIATIONS OF MRNA TECHNOLOGY BOOSTERS AND SELF-AMPLIFYING MRNA “VACCINES”​

View: https://rumble.com/vvfu43-variations-of-mrna-technology-boosters-and-self-amplifying-mrna-vaccines.html?mref=uowm5&mrefc=2

By KATI SCHEPIS, PHARMACIST WITH ASSOCIATE PROF. By KATI SCHEPIS, PHARMACIST WITH ASSOCIATE PROF. MICHAEL PALMER MD
SESSION II THE FUTURE - SCIENTIFIC AND LEGAL ASPECTS WITH ASSOCIATE PROF. MICHAEL PALMER MD
D4CE Symposium III with Highly Acclaimed International Scientists, Lawyers and Economists held on February 18, 2022.
Gold Standard Covid Science in Practice – An Interdisciplinary Symposium III: THE TRUTH SHALL SET YOU FREE

https://howbadismybatch.com/selfamp.html

What are these 3 types of vaccine, and how do they differ in effects ?

1. Non-modified uridine containing RNA (uRNA) : RNA consists of a string of letters A C U or G. Where A = adenine, C = Cysteine, U = Uridine and G = Guanine. Non=modified RNA (uRNA) contains these 4 letters. Our innate immune system can detect non-modified RNA and destroy it.
2. Nucleoside Modified RNA (modRNA) : In this RNA, the Uridine is replaced with Pseudo-Uridine, so our immune system can nolonger detect it.
3. Self-amplifying RNA (saRNA) : Self-amplifying mRNA (saRNA) vaccines are similar to conventional mRNA vaccines, with the exception, that saRNA vaccines also self-replicate their mRNA. The self-amplifying mRNA has two open reading frames. The first open reading frame, like conventional mRNA, codes for the antigen protein of interest. The second open reading frame codes for an RNA-dependent RNA polymerase (and its helper proteins) which self-replicates the mRNA construct in the cell and creates multiple self-copies. Wiki. Self replicating RNA generates 64 times the amount of antigen (spike) compared to non-amplifying RNA, and as a consequence produces a much stronger immunogenic response - see - Study. Besides producing more antigen, self-amplifying RNA produces antigen over a longer time. See - Study

This paper states that self-amplifying vaccines can replicate for up to 2 months.

mRNA vaccine for cancer immunotherapy - Molecular Cancer

mRNA vaccines have become a promising platform for cancer immunotherapy. During vaccination, naked or vehicle loaded mRNA vaccines efficiently express tumor antigens in antigen-presenting cells (APCs), facilitate APC activation and innate/adaptive immune stimulation. mRNA cancer vaccine precedes...

molecular-cancer.biomedcentral.com

There are ongoing clinical trials using self-amplifying COVID 19 "vaccines" with human subjects. One of these trials is with 500 subjects in Germany. This is a phase 2 trial, and its completion date is set for April 2023.