ORN 4_19_21: mRNA Vaccine Dangers, Immunity, Nutrition

meatbag

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Link to audio interview:Ray Peat Interview - April 2021 - One Radio Network
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PT(introduction) : You say you’re having a little heat wave up there doc?

RP (1:56)- Yeah in the 80’s

PT (1:58)- Really, that’s unusual for you guys

RP (2:00): Very for this time of year

PT (2:03): Are folks in Oregon, is everyone masking and getting out? What’s the story up there?

RP (2:13)- Some of them are getting away from it, now and then I see someone without a mask. But it’s still official here. Every once in awhile you see someone jogging with a mask one even though there’s no one with hundred or thousands of feet haha

PT (2:33): Do you have any sense of it after all of this time? I mean, who knows what is really going on. What is your sense of it?

RP (2:48): Uh, there’s not really any evidence it should or does, it could of course but that’s a really weak basis for requiring millions of people...

PT (3:07): Sure, sure. After all of this time do you have a sense of what’s really going on here?

RP (3:18): So far I still haven’t seen any evidence of a pandemic, there’s lawyers around the world suing the governments to reveal the scientific basis for the lock downs and the masks and all of that they're keeping it secret if there’s any scientific bass. Yesterday I saw that Michael Yeaton, the former Pfizer Vice-President, has made another statement and he says the science behind it is so non-existent that he’s accepting that there could be other motives. From what’s known about the spike protein and the RNA so called vaccines, that it’s very probable that they could have long range degenerative effects, breaking down organs over the coming months or even years. And that one of the possibilities is that it’s intended to DE-populate the world.

PT (4:47): And this is a former Pfizer fellow that’s saying this?

RP (4:51): Yeah, Vice-President at Pfizer and then he was cofounder of a biological company that sold later for 225 million dollars or something so he’s had a lot of experience in work related to viruses and vaccines.

PT (5:17): hmm. Is there, was this, any of the talk from this Pfizer fellow mainstream? Or was it all alternative?

RP (5:25): Naturally, they censor his videos, but I saw a long talk and people tell me he’s released another video but when you look him up on google you find about twenty-headlines; “Micheal Yeaton(*), former Pfizer vice-president” fake news haha putting out many derogatory remarks before you can find what he actually said.

PT (6:10): We’ve heard this term- Spike protein – with this injection, could you explain to us what this is?

RP (6:15): Uh yeah, the workers at North Carolina in the Virus department (*)published several papers, a long series, about 10 years ago, about how you can remove the nucleic acid section that describes specifically the protein that allows the virus to attach to human cell surfaces, so that if you inject that into an animal virus you can make it stick to certain receptor on human cells. The current Corona viruses contain this adhesive protein, which in the process of making the virus stick to the surface of our cells, inactivates the protein that it sticks too and that protein, the ACE-2 enzyme, angiotensin converting enzyme number 2, happens to be the degrading proteolytic enzyme that breaks down angiotensin to which is the promoter of high blood pressure, inflammation, degeneration, and all kinds of bad things in our body. And so ACE, the Angiotenin converting enzyme, they found that if you block that, or if you block the actions of the angiotensin 2, the short peptide, that you can relieve high blood pressure and at the same time it happens to relieve nerve degeneration.
(8:27)They’re trying it in Alzheimer disease. Kidney disease, muscle wasting, age related muscle deterioration, muscle shrinking. Everything that aging and stress has been known to do, hypertension and cancer, all of those things. Are promoted by angiotensin so if you block them then you get these very surprising therapeutic results. And very early people found that these blood pressure drugs were therapeutic for the coronavirus infected people. But the medical establishment said “Well, that protein, ACE-2 enzyme is where the virus sticks, if you increase that enzyme, you’re going to make yourself more susceptible to the attachment of the virus. But it happens that if you don’t have an abundance of that enzyme, you’ll have have an over supply of the pro-inflammatory and degenerative angiotensin peptide. So the medical journals for a while were full of advocacy for blocking this protective enzyme, but the facts turn out the other way. Promoting the ZCE-2 enzyme turns of out to be a radically important defense against infection and symptoms.

PT (10:29): So then what are we conjecturing then that the folks who are concerned, that get this jab, what it’s doing to them?

RP (10:39): That it’s causing our own bodies to start producing this horrible spike protein that knocks out our basic defensive anti-inflammatory system. That’s the sort of thing that people like Michael Yeaton are talking about. It’s leading one of the most horrible possible proteins to be produced by us adopting the RNA from the virus, so that we become virus-like, and produce our own toxic, pro-inflammatory protein.

PT (11:24): So that’s the reason why there’s so many arguments with the Tenpennies around and (intelligible), he’s gonna be in tomorrow, that there could be some really detrimental long term effects of this thing?

RP (11:35): Yeah, just out of thin air people like Fauci say “O, that isn’t how the cell works. The cell can’t integrate that into our genes, can’t reproduce that” (*). Just no evidence he’s right. For over 50 years we’ve known that our bodies have reverse transcriptase that can integrate it into our genome permanently. A group at Harvard and MIT published in-vitro research showing that in fact human cells can and do incorporate the vaccine RNA section into the genes of the cell.

PT (12:20): So, the CDC, they gotta know this, right? Aren’t these scientist? (lol) Don’t they know this?

RP (12:40): If you look at the history going back 100-years of the US public health service and the CDC, they don’t have a good record if you look at the actual un-publicized things they’ve done, experimenting on (*) children, going into Guatemala to test dangerous...infect orphans for example to experiment on. It’s really just something out of a horror movie, the actual history of the CDC.

PT (13:30)- Wow, we’ve had so many people talk about vaccines in general over the last 18-months. This idea that a vaccine, and I guess the live ones without the adjuvuncts, are safer in theory, that they disrupt the innate immune system. So do you think that all vaccines do, disrupt the innate immune? The God-given immune system that we have?

RP (14:05)- Uh yeah to the extent that you over activate the anti-body producing system. That’s sort of the superficial, visible part of the immune system. It really derives from the imaginary side chains that Paul Ehrlich invented to sell his drugs at the beginning of the twentieth century. It’s really a doctrine that came form the chemical industry that turned into the basis of official government and corporate description of how immunity works.
(14:53) If you have antibodies supposedly you’re immune. But meanwhile actual science was showing that plants have learned immunity. You give them a trace, a vaccination and you sensitize the system. And a few days later, that same trace amount that was harmless can become deadly, because you’ve created an allergy. And that same thing happens in animals. A trace of something that is harmful but not deadly can activate an over sensitivity that causes sickness.
(15:45) The junk that goes along with any vaccine is a risk, it’s the way you create experimental allergies in experimental allergies in experimental animals, is to give them a little bit of extraneous material, wait two weeks, come back, and give it to them again and you’ve created an allergy in the animal. So that’s is one of the side-effects of just about any vaccine.

PT (16:22)- Any vaccine. We’ve had...(cuts off)

RP (16:28)- And so allergies have been one of the fastest growing problems in the United States

PT (16:34)- In our culture. And just in animals, we’ve had some that all of the vaccines they give the animals, I had one girl that itched two or three years before she got over it. Jut wow...

RP (16:50): Mhmm

PT (16:53): So I guess in theory from a real perspective, like the plant you mentioned, and generally it’s not going to I guess, we have some way to deal with it?

RP (17:12)- Yeah, all of the whole organism, all the different levels will adjust and toughen up. So there’ not really any part of our organism that isn’t involved in immunity and resistance. The ability to produce energy efficiently is really our most basic immune process.

PT (17:47)- Every cell, everything in our body, this life-force that we embody, Chi or Spirit or whatever you call it. It’s really involved in resisting anything that’s assaulting it.

RP (18:04)- Yeah, sustaining itself.

PT (18:07)-That’s what it wants to do

RP (18:12)- Yeah and there are two well known counter culture researchers, Polly Matzinger with the Danger-theory of immunity, and Jamie Cunliff (*)with the Damage Theory of Immunity. Cunliff specifically says that our immune system isn’t aimed at viruses and germs, its aimed at maintaining our own life process. When something damages the tissue, the body goes into a repair process and that includes things like antibodies that in the process of removing damaged tissue and creating a repair integral tissue in the organism, in the process the antibodies will take away any bacteria or virus that happen to be involved in damaging the tissue. But the aim of the organism is self-sustaining and repair and maintenance not trying to predict any future micro-organism that might get into us.

PT (19:45)- So is that an argument for to not...to mess with these bodies as little as possible? In general?

RP (19:52)- Yeah, in Africa, the poverty and climate, a very humid and hot climate supports a lot of possible parasites and infections, as well as the poverty. Has exposed the population to a lot of challenges. When they were looking at the so-called AIDs epidemic in Africa, it turned out that almost everyone had the apparent AIDs or HIV exposure. But the really convincing explanation of that was that their immune systems had been overburdened and weakened. The self-maintaining and restoring processes had been weakened. The appearance of the extreme degree of infection with the HIV virus was just a reflection of general tissue injury.

PT (21:15)- So they were weakened because of lack of nutrition?

RP (21:17)- Yeah.

PT ()- Just a tough lifestyle with the sanitation and poverty and everything like that.

RP (21:27)- Yeah, several big studies have experimented just adding a vitamin D supplement or vitamin A supplement and just that has made a far bigger difference. Far better than vaccine campaigns.

PT (21:50)- Wow, so that’s why so many people in Africa had the AIDs virus and why they were given these drugs that is said to have killed so many people?

RP (22:03)- Yeah, Peter Duesburg proposed that. He said that his experience with viruses, he was really the pioneer in Virology, in a lot of ideas, he said he didn’t see any way that the HIV could create immunodeficiency. So the reaction to his observation was to stop granting him research support and to to stop inviting him to conferences so he couldn’t speak publicly.

PT (22:44): Fascinating. So if you’re back 50 years ago and starting a family would you vaccinate a kid for Measles, Mumps, Rubella?

RP (23:10)- No the issues back then were just like now. There was a counter culture. In the 1940s and 50s there were people warning about the dangers, warning about polio. There were publications all of the way back to the twentieth century showing that injecting anything into the muscle, even vitamins injected intramuscular, preceded the outbreaks of paralytic polio

PT (): Preceded the outbreaks? The injections?

RP (23:48): Yeah the injections. Yeah when they looked at the kids that came down with paralysis in a particular leg or arm, it turned out that had been the site of some kind of injection. Vitamin injections or vaccinations.

PT (24:12)- Wow, and there is people arguing that DDT played a role in the whole Polio thing.

RP (24:20): DDT? O sure, it damages, it’s an estrogenic substance and one of the things the spike protein does, creating increased Angiotensin and Angiotensin increases estrogen(*),it activates the aromatase enzyme, as well as prostaglandin synthesis, the prostaglandin in turn activates aromatase and creates a whole cascade toward producing more estrogen. And so angiotensin and estrogen symptoms turn out to be very parallel and so DDT or various plastic plasticizers that are filling the environment now, these have strong estrogen-like effects and so they overlap with the effects of the virus.

PT (25:36)- So all of these poisons round up, or any kind of poison, toxins, these turn out to be the chief culprits with what we call disease.

RP (25:50)- Yeah weakening the restorative, energetic system.

PT (): “Weakening the restorative, energetic system.” Were talking about the Chi, the life-force, weakens it. Which is what happens when we eventually die. The life force gets so low that we just die.

RP (26:14)- Yeah, that’s what I’ve been writing about in my newletters the last several months. What is it that causes us to gradually, or more or less suddenly, after about 70 or 80 years, to have a collapse of that restorative energy system. Basically I’ve been arguing it’s the accumulative effects of adapting to defective systems. One of the things you can see in the environment is the altitude effect.
(27:00) When you’re at low altitude where most people live along the coast, the Oxygen pressure is much, much higher than the developing embryo and fetus experience. And at the CO2 that we produce, but that the gestating fetus can retain, being enclosed in the Uterus. The Oxygen is much lower and the CO2 is much, much higher and that balance favors the fantastic development from one cell to this high metabolizing, big brained, big at birth, with a metabolic rate two or three times higher than an older individual. So this extreme support for perfect development, preventing scarring if there’s a tissue injury during gestation, the high CO2 and low Oxygen tension, prevents the formation of scar tissue. But once you get out and into this excessively Oxygenated environment then injuries tend to form scar tissue rather than good maintenance, complete repair. So where the highly energized vital young and resistant system produces tissue restoration without scarring. The weaker you are, the poorer your nutrition or the more toxic exposures, the more likely you are to replace good tissue that’s injured with what is more or less scar tissue.
(29:15) And aging consists of a shift from vital functioning cells to fibrotic inflammation, scar-like tissues.

PT (29:30)- It doesn’t seem like it’s really a natural process; aging. Aren’t we kind of wired up to live scar free and a lot longer than we are as a culture?

RP (29:43): Uh yeah. I think one of the things that causes that is that our environment now has too much Oxygen and not enough Carbon Dioxide.

PT (30:00)- How can we retain more Carbon Dioxide?

RP (30:04)- Moving to a 8,000 or 9,000 feet altitude. Leadville Colorado if you can adapt to it. The heart disease, cancer, and dementia rate goes down every thousand feet higher you live in altitude, the lower the cancer and heart disease.

PT (30:24)- Wow is that right? So just because more CO2 is retained?

RP (): Right

PT (): So when we exercise, we actually get rid of CO2, is that right?

RP (30:41): If it’s bad exercise.

PT (30:43): Bad exercise? What would be good exercise in your opinion?

RP (30:47): Anything that raises your body temperature it turns out that the good exercise that has prolonged effects is anything that raises your body temperature by muscle heat production and they’ve compared exercise to just warming the body and you get the same anti inflammatory anti heart disease, anti cancer effects and so on, just by getting your body temperature up which good exercise does.

PT (31:22): And in your opinion good exercise is?

RP (31:26): Heat producing

PT (31:28): Which would be? Examples?

RP (31:31): Muscle resistance exercise; lifting wights, walking, running in short bursts, but it’s the prolonged breathless kind of exercise where you become hypocapnic; very deficient in carbon dioxide,

PT (31:56)- So if we can figure out how to exercise without...by breathing normally, than we’re doing good? We’re not decreasing our Carbon Dioxide

RP (32:09)- Yeah, you’re increasing Carbon Dioxide and that decreases the inflammatory production of lactic acid

PT (32:20)- And we can do that as our heart and our blood vessels and our muscles get stronger, right? And we can retain more of that Carbon Dioxide

RP (32:25): Mhmm, yeah. The muscle adaptation to exercise increases the volume of the muscle and the ability of the muscle to produce productive steroid hormones rather than destructive estrogenic hormones

PT (32:49)- Fascinating. So that why so many of those people, remember when the jogging was the big thing and these guys were dropping like flies? Well not like flies but ya know. And I think the most famous guy was James Fix and he was running like 25 miles at a time. But don't those folks down in Africa run a lot? Or maybe they’re just walking

RP (33:17)- Uh yeah and in areas of Northern Mexico there are people who have to travel 20 or 30 miles a day and they do it at a rate that, bu they do it at a high altitude, and the high altitude allows you to do more and still retain you’re CO2.

PT (33:48)- Yeah, we heard from Stephanie Sinifa (spelling?) she has a new book out on glyphosates and she says Mexico is going to be completely banning glyphosates in the next year

RP (34:00): That’s very good

PT (34:01)- Yeah, wow. We may need to move down there. I just want to give a heads up, I thought I’d get some of the Thyroid, but I didn’t get it and it showed up in Chicago and I got a notice from the FDA and they said you don’t need it. What’s the name of the place..?

RP (34:56): Farmacia Del Nino

PT (): Yeah, they were very nice and they said we got you’re thyroid back and would you like it back or would you like your money back and they’re very reputable, very friendly. They didn't have to do that, I would’ve never known

RP (35:16)- Yeah, quite a few people have sent them cash in an envelope and they get their order alright

PT (35:35)- So that’s a reputable company at any rate. Stay right there were gonna take a break and then get some email questions Commercial Break

PT (40:44)- We’re talking with Ray Peat, you can subscribe to him by email at raypeatsnewsletter(at)gmail(dot)com. So your most recent newsletter you’ve been looking at why we die, is that right?

RP (41:05)- Basically, that isnt the title but its looking at the process of adapting badly.

PT (41:20)- How big of a deal do you think it is when people get to like 60 or 70 and people start thinking they have nothing to live for? I mean that’s gotta be huge on the organism, isn’t it?

RP (41:41)- Yeah, animal experiments show that isolation, or the creation of hopelessness or the expectation that you don’t have a future, that very proccess of isolation, the expectation turns on the pro-inflammatory processes which creates tissue inflammation, accelerating tissue degeneration

PT (42:05)- So that idea, I don’t have anything to do, maybe I’ll just watch T.V., it’s going to damage the tissues?

RP (42:25)- Yeah, turns down the energy system, raises the inflammation processes.

PT (): Fascinating

RP (42:27): It’s part of the adaptive processes. If you don’t intend to keep adapting to interesting, exciting stuff, then...

PT (42:45)- New stuff. So if we tell our body we’re not interested in adapting, we’re just gonna go hide or escape, then the body will get weaker?

RP (42:53)- Yeah, It accommodates the process and gets weaker, turns down your interest and ability to keep adapting

PT (): So what would be the opposite way? So that could be the hypochondriac kind of like you try to do so much stuff, you get afraid of stuff.

RP (43:20)- Uh yeah, a part of the same process, looking at the body as a machine rather than a self with plans

PT (43:36): Haha, a self with plans, that’s great. We’re going to take some emails. Here we go;
“Doctor Peat, many herbalist and naturopathics recommend the herb Milk Thistle for liver health and repair, I find online that it is estrogenic, so no surprise that it knocks down my libido each time I use it. As an alternative I’ve started using NAC, for liver protection. I know that cystiene is one of the amino acids that Dr. Peat cautions against getting too much of. So what does he recommend to protect the liver form say alcohol abuse or prescription drugs while living on planet earth, without affecting my libido?”

RP (44:22)- In experiments with alcohol toxicity, alcohol exposure creates a fatty and scared liver, the immediate antidote to alcohol poisoning of the liver and other tissues is fructose. People have been saying that fructose is poison for the liver like alcohol, but it’s the opposite. Fructose is the antidote to alcohol poisoning. Fat metabolism doesn’t produce as much Carbon Dioxide as sugar or starch metabolism, and so as long as you can keep oxidizing starch and sugar effectively, you’re producing the protective Carbon Dioxide.
(45:21) Anything that makes you shift the balance away from oxidation and carbon dioxide is harmful. Too much reductive balance, if you look at the niacin related metabolites; NADH and NAD. The healthy oxidizing cell has a higher ratio of NAD to the reduced NADH. A lot of...the whole 70 or 80 years of thinking about the dangers of oxidative peroxidation started with the realization that polyunsaturated fatty acids oxidize spontaneously and cause toxic effects. So this whole culture of fearing oxidation and wanting antioxidant processes or reductive processes have promoted the idea of things like reducing agents like cystiene or glutathione, has been a big thing. They inject glutathione, because it has been so powerfully antioxidant, but in fact the reductive stress turns out to be the real harm done even by what they thought was oxidative stress. Because when you fail to oxidize vigorously the excess electrons find their way to iron atoms for example that had been harmless. The electron excess turns the iron into an oxidative destructive center. So the tendency to fail to oxidize turns on the process of random destructive oxidation. Substances like the flavonoids that you find in fruits and vegetables and milk if the cow has been eating well, these bioflavonoids activate the cell’s oxidative processes, even though they had been sold as reductants, antioxidants, their effect on the cell is to increase oxidation of the good sort and to consume electrons faster and by that to reduce the random destructive oxidation.
(48:25) So if you just put in more cystiene or more glutathione or even too much vitamin C. The vitamin C that is effective and working in the cell is as a pro-oxidant. It’s dehydroascorbate that works in the healthy cell. Cancer cells shift to a reducing, reduced form of all of these things; glutathione, cysteine, and ascorbic acid its self rather than dehydroascorbate. So the healthy tissue is on the balance, a continuously slightly oxidizing process.

PT (49:20)- So that’s why you’ve never been a big fan of just doing a bunch of vitamin C, or any Vitamin C really.

RP (49:30)- No, Linus Pauling pointed out that the Gorillas who can’t synthesize Vitmain C the same as people, they on their natural diet are consuming about 4,000 mg of vitamin C a day. All of the animals on a natural diet, consume the equivalent of 3 or 4,000 milligrams of vitamin C just in ordinary foods. Milk, meat, eggs, all of those things, if the animal was alive it was producing its own vitamin C.

PT (50:12)- But it’s out of food and not from ascorbic acid?

RP (50:18)- Yeah, if you put in too much ascorbic acid you can run the risk, same with intravenous injections of Glutathione. Any strong excess of reductant in the bloodstream can create oxidative damage. For example an experiment, free radical chemist, was testing the reagent grade, purest available Vitamin C, much higher standards than USP vitamin C. Put a gram of that in a liter of ultra-distilled water and found that in an apparatus to measure free radicals that it was producing from the Vitamin C and whatever trace metals contaminating the highly purified Vitamin C that in distilled water it was producing free radicals at the rate that a killing dose of x-rays would produce. Just the slightest trace of Iron for example, that was the particular metal that the free radical chemist identified reacting with the Ascorbic Acid.
(51:50) And in your body when you have an excess of reduced Vitamin C taken in it finds Copper and Iron and that reacting couple will inevitably find some Polyunsaturated fat to make rancid instantly, so the combination of a trace of Copper or Iron plus Vitamin C, plus fat creates extreme lipid peroxidation.

PT (52:25)- So is that an argument for maybe giving blood now and again to get rid of some excess Iron?

RP (52:30)- O yeah, thats one of the benefits.

PT (52:34)- So that where the whole blood letting thing at one point came form?

RP (52:42)- Yeah it turns out to just, people felt better after donating blood very often. They experimented on animals and they found that old decrepit dogs for example could be rejuvenated by taking the blood out, washing it, and putting the red blood cells back in without the serum and doing that repeatedly, washing the blood removed a lot of their aged qualities. And if you join the circulatory systems of an old rat and a young rat, the old rats life is extended while the young rat goes through its life span.(*)

PT (53:33)- Going back to the fructose, so is that one of the reasons why you’re such a fan of orange juice?

RP (53:40)- Yeah, but the flavanoids are another

PT (53:45)- And thats in Milk too?

RP (53:47)- Orange Juice and Milk are very safe ways to get a very high intake of the bioflavanoids. (*)

PT (53:55)- Bioflavanoids. So where did all of this stuff come from that we shouldn’t be drinking milk? All the anti-milk stuff? Its crazy isn’t it?

RP (54:12)- Yeah, my aunt was a nurse trained in the 1920s and 30s and she was indoctrinated to not breastfeed her kids and that was big medical thing that there was some kind of a supposedly biological stigma against breast feeding. So they were feeding them artificial milk, and the idea of making milk out of seeds, almonds, seeds, soybeans, developed out of that baby food culture, turning it over to industry rather than the mother. That developed, I think it has Freudian implications in the motivation, that people are so fearful of milk.

PT (55:18)- I see. You had mentioned earlier about well fed cows, so are we just talking about grass fed, because if they’re not grass-fed you just don’t know what they’re eating?

RP (55:27)- Uh yeah, fresh grass has the most and highest content of flavanoids, hay is fairly good, so dried grass still has a lot of stuff. A highly grain concentrated diet is the worst.

PT (55:48)- And you could actually, if you don’t have a source locally, you could actually I’ve seen organic grassfed milk at whole foods, so you can buy it if you want.

RP (56:02)- And the flavanoids are a great virtue

PT (56:05): So that’s in there. So that another great argument to find grassfed butter. Like the ones we get from Ireland or something.

RP (56:11): Yes, even the butter will contain the flavanoids.

PT (56:17): Ben wants to know, he’s 71, and he wants to know “What is the best regime to increase low Testosterone and gain more muscle?” He wants more muscle and more testosterone. So what are your favorite things?

RP (56:30): Yeah, shift the diet away from fats to some extent. Increase the carbohydrates, especially orange juice is one of the best. But any carbohydrate is better than more fat.

PT (): Wow really? So many people say fats are so good for us? Could you talk more about that?

RP (57:02): The saturated fats going back to Hans Selye’s experiments in which the rapeseed oil was considered to be heart toxic so they developed Canola oil, with I think it was Erucic Acid which was reduced , but Hans Selye showed it was linoleic acid, which is still to high in Canola Oil. Hans Selye showed it was the high Polyunsaturated fats that were causing heart cell death. He would slice up the rat’s heart after they had eaten that high PUFA diet and find dead heart cells all through the tissue. But then he fed them besides the same amount, he didn’t reduce the PUFA, but he added a lot of coco butter. Which is very high in stearic acid. And just by getting the very saturated long chain fat to balance and protect against the PUFA, he eliminated the heart death.

PT (58:18): Hmm, so it would be good for us to have a little coco butter? You can actually buy that to hm?

RP (58: 23): Yeah, I just got some, the deodorized, the odorous stuff can sometimes be very allergenic.

PT (): It’s just white isn’t it? It’s made from Cocoa, or raw chocolate

RP (58:44): Yeah, if you have the unrefined coco butter, its white but it tastes like chocolate so you can make white chocolate. It’s important to check for allergenicity, even with natural coco, because the way it’s fermented and prepared can cause allergies.

PT (59:14): So back on the muscles and the more you say more carbs, does that rice and pasta for muscles or not? Or just more fruit?

RP (59:27): Fruit is higher in the protective flavanoids, the grains are very low in them. But then the protein should be adequate. You don’t want too much of the methyl donors, the age promoting amino acids are mostly cysteine and methionine, so you want to moderate those. And then the type of muscle activity, like using dumbbells and squats, just a few of those like 10 repetitions of dumbbells or 10 squats or sit-ups will build muscle volume.

PT (): What about animal fats? Porkfat or beef fat or things like that?

RP (1:00:32): Beef fat is rich in stearic acid and mono unsaturated fats. Pork fat can go all of the way up into 30% linoleic acid, which is very age promoting. But there’s one pork farm in Maryland that has experimented with feeding a good high carbohydrate diet to their pigs and they got their PUFA content all of the way down to 4%. And beef fat can be as high as 3%. So their pork was very competitive with beef for safety and high stearic acid content

PT (1:02:22): Interesting. So the pigs that are fed maybe GMO corn and other stuff could be a real issue, but if you find a farmer that is doing more vegetarian and more fruits and vegetables and stuff then that could be just fine?

RP (): Yeah

PT (): Yeah, that’s cool man. So smoothies are good for us? Fruit smoothies?

RP (): Yeah as long as you don’t put raw seeds and nuts and vegetables

PT (): All that stuff. You don’t put that stuff right?

RP (): Mhmm

PT (1:01:57): What’s the best thing we can do writes Carol for a system that is usually alkaline? I guess she’s feeling too alkaline? Are vegetables okay?

RP (1:02:10): Umm yeah, cooked vegetables are a way of getting a well balanced carbohydrates but proteins are the main thing that acidifies our system, so if your urine is more acidic, you’re much less likely to get kidney stones than people on a high alkaline diet. So the people on a very vegan or excessively vegetarian diet are much more likely to get kidney stones because the material crystallizes and deposits at a higher pH.

PT (1:03:02): I see, so our urine wants to be more in the 5-6 range?

RP (1:03:09): Yeah, and exercise producing carbon dioxide is one of the things that will help to keep your blood and urine slightly on the acidic side. Well, not acidic for the blood. The less alkaline system, higher carbon dioxide, slight tendency toward Hypercapnia is highly protective to all of your cells.

PT (1:03:38): Mhhm, we’re here with Dr. Ray Peat, he’s on the third Friday of each month. You can email raypeatsnewsletter(at)gmail(dot)com and he’ll get you set up with a subscription to his newsletter. Here’s an interesting question here, from Ryan, on this 19th day of April; “My girlfriend’s cycle has shortened to three weeks the last couple of months lots of unvaccinated women are reporting this recently after their friends have gotten vaccinated. Could they be passing anything from the vaccine? many coincidences but a lot of people are talking about it? Any scientific reasoning behind this?”

RP (1:04:33): People have been contacting me about that.

PT (1:04:38): I’ve seen stories too. Is it possible these vaccines, injected people are shedding something to girls?

RP (1:04:46): It is an obvious possibility. It hasn’t been...People haven’t done testing of swabs of their skin or their exhaled breathe or so on, but it is a definite possibility that exactly just as the virus can be exhaled or put into the sweat and urine, the vaccine RNA, obviously can go the same route and the spike protein, by knocking out ACE-2 enzyme increases angiotenisn, angiotensin increases aromatase, aromatase increases estrogen and prostaglandins, and estrogen and prostaglandins are deeply involved in regulating the menstrual cycle and creating PMS, Dysmenorrhea, Aminuria, changing of the length of the cycle, and so on.

PT (1:06:00): And you’ve been contacted by ladies that are experiencing some shortened cycles?

RP (1:06:03): Yeah. Just recently.

PT (1:06:05): So is it possible that people who’ve been getting this injection could actually breathe out stuff we don’t want or share it?

RP (1:06:18): It’s logically just as possible as with the viral material, its… our breathe contains the most surprising assortment of chemicals. Peptides, bits of nucleic acid, exactly the sort of thing that could carry virus like fragments of RNA. You can even find isoprene in exhaled breathe.

PT (1:06:47): Well this is crazy, maybe we’ll get to the point where all of the unvaccinated people will have a passport showing how healthy they are or something haha

RP (1:07:01): That’s implied by people like Michael Yeaton

PT (1:07:05): I guess that could be where we’re going. Wouldn’t it be something if it all ended up like that a few years from now. Here we go; “ I know you’ve mentioned Dr. Zachary Bush previously in a few shows. He makes a product called ‘ion gut health’ the ingredients are aqueous, humous substances. Do you think there could be any value in taking this?”

RP (1:07:30): No, humic substances, it’s just a component of dirt. Probably harmless

PT (1:07:49): Component of dirt. Probably harmless. People have argued that if you have an organic garden you don’t have to wash the vegetables that well. Is that true?

RP (1:07:55): That’s true.

PT (1:07:57): Is it. You get a little bit of good stuff in there?

RP (1:08:02): Yeah haha a little dirt is completely harmless

PT (1:08:05): Kids eat dirt all the time right? haha. “ My wife’s recent CAT scan with no contrast showed a mild mucousal thickening on the right side of the sphenoid sinus. Should she be concerned? If so, what would you suggest?” Asks Henry

RP (1:08:25): Allergies will cause a thickening, something you ate getting into the blood, the endotoxin from bad digestion will circulate through your body causing sinus membranes, nasal membranes, lungs to thicken up and have symptoms of inflammation; itching, burning, all of the inflammatory symptoms.

PT (1:09:02)- We’re with Doctor Ray Peat, this is the 19th of April. Next week Dr. Jennifer Daniels is the lady who is going to talk about the illusory benefits of the Fourth Industrial Revolution that is being promoted by the World Economic Forum. Also Dr. Shiva, you’ve heard of him. Forest Rivers, who is talking about how this is a great awakening, just hold on, everything is going to be okay. And Richard Mayberry is gonna be here, so we have a full week for you next week.
Here’s a question; “Is cultured butter a health asset? What about Kefir?”

RP (1:09:40)- O, Kefir is probably okay if it isn’t very sour. If it has too much Lactic Acid, drinking a large amount like a pint of it, it can upset your liver and can give you a headache. So you just have to be cautious with the quantity and the acid content. But there’s really no benefit to culturing butter. They add strange industrial microorganism by products to change the flavor I guess. But just butter itself the pure fresh form that condenses when you shake up slightly soured milk. The milk if it’s naturally soured has bacteria cultures in there.

PT (1:10:38)- Do you think that if you have raw say grass fed milk from a goat or cow that you can just leave it up on the counter in room temperature and it’ll do stuff? Does that make good things?

RP (1:10:48)- That’s the way we would make cottage cheese for example. If you want to make butter you can let it stand for a few hours and still have sweet butter. But the idea of buttermilk was because if you left it out for 8 or 10 hours it would start growing bacteria. The bacteria would come in from the air if they didn’t come form the cow. And the souring milk would create faster making of the butter.

PT (1:11:35)- Is goat milk close to being as beneficial as cow milk? Is it similar?

RP (1:11:40)- Yeah, largely its the diet. Goats prefer grazing on leaves and are more reluctant to eat stuff like a high grain based diet and so their milk will have a lot more of the flavanoids than the average grain fed cow milk.

PT (1:12:00)- Do you think if you had a goat or cow that was eating genetically modified or just the glyphosate laden food, which a lot of the corn and stuff is, that could be an issue?

RP (1:12:15)- O for sure.

PT (1:12:16)- For sure. You don’t want to do it.

RP (1:12:18)- No

PT (1:12:20)- Mike wants to know; “Recent studies show the anti-inflammatory benefits of specialized pro-resolving mediators, SPM’s, which are cell signaling subclass of omega-3 PUFA’s. I know Dr. Peat’s stance on PUFA’s, but is there a place for using SPM’s in managing inflammation?”

RP (1:12:45)- A couple of researchers one of them named “Sethi” traced the fate of DHA and EPA after they were ingested and he found that by the time they reached the bloodstream they were mostly oxidized and breaking down into other substances such as those and that it’s those oxidized products which are so immunosupressive. You can call immunosupression an anti-inflammatory and resolving function but I think it’s a dangerous way to resolve inflammation. I think of it as sort of analogous to the old treatment of arthritis with radioactive water. You can knock down inflammation with radiation. They used to treat acne with x-rays. You can temporarily reduce inflammation with high PUFA content, oxidized fragments, or you can create the oxidized fragments quickly with x-rays.
(1:14:11) But the long range effect is that you had a destroyed face and head from the x-ray treatment.

PT (1:14:21)- So the oxidation of the biomolecules is really, that’s where disease starts?

RP (1:14:29)- Partly, yeah. It’s a suppressive energy lowering process.

PT (1:14:37)- So all of these poisons and chemicals and anything. This is one of the chief causes?

RP (1:14:48)- It slows down oxidative energy production and we compensate by increasing the glycolitic lactic acid processes that shifts the whole organism toward degeneration.

PT (1:15:03)- The lactic...that’s tied in with myocardial infractions and stuff with the too much lactic acid?

RP (1:15:15)- Yeah yeah. It shifts cells in the same direction so it’s a self-promoting, degenerative factor.

PT (1:15:30)- Doctor Cohen who talks about the over lactation of the heart muscles especially, likes this herb from Brazil, have you heard of that one? I don’t know how to pronounce it properly, its a climbing vine out of Brazil

--Discusses a herb from Brazil and Digitalis--

(not exact)RP (1:16:00)- Strophancus its called wahbane and its a steroid glycoside that we make. Its in ourselves and in aging metabolism a slight supplement of that can be therapeutic. It’s similar to digitalis.

–----
PT(1:17:13) - What food increase Carbon Dioxide? Sugar? Oranges?

RP- Yeah Orange juice is great.

PT- Do you drink a lot of it?

RP- Yeah haha

PT- Haha yeah no doubt about it.

RP- In Mexico where sweet oranges are sweet and easy to get I would juice them and always have a lot of juice.

PT- Does Dr. Peat have an opinion on the blood flow restriction training

RP (1:18:24)- Injuring the muscle will make it grow, but that’s the extent of it, your still hurting the whole organism.

PT- I see so you’re hurting the organism, you’re damaging the muscle making it bigger but for the whole organism, that’s not good.

RP- (1:18:45) They’ve looked at the mitochondria of old people which are much less efficient than young people’s mitochondria and then they had them do only concentric exercise, only contraction against resistance, no extension of the muscle under force. And with just a few weeks of exercise they had created new young-like mitochondria in these old people. And its the eccentric exercise like running or walking downhill or letting a weight down rather than lifting it, stretching and extending the muscle under resistance. That’s the eccentric muscle damaging kind of activity that causes the most muscle growth. So if you want big muscles, but not necessarily the best health, you can do eccentric muscle tearing exercises

PT (1:20:05)- That’s tearing right?

RP- Microscopic tearing damage

PT (1:20:05)- You know Doc, I’ve been doing some really deep stretching, a lot of it the last three months and my legs and body have never felt stronger in my muscles. That’s what it’s doing right if your stretching?

RP (1:20:20) – Yeah just its mostly the activation of the muscle

PT (1:20:25) – There’s no resistance to it, I’m just stretching.

RP- (1:20:33)- You don’t want to force elongation of the muscle against resistance.

PT- That would be counter-productive, that way?

RP- Yeah

PT(1:20:45)- Here’s Dana ,she has no thyroid, since a person with no thyroid has to take a full replacement dose, what does he see as a probable... the minimum of taking cynoplus and how best to take it, the minimum to take it. He has said 3-4 mg’s per hour. If you take more than that per hour, is it going to turn it into reverse T3? It’s hard to be on a 1 hour schedule with thyroid medication all day everyday.

RP (1:21:29)- Yeah, you can usually get by taking it with a meal, the meal will delay the absorption so its more or less natural in the way its absorbed by the cells, a little with each meal.
The overall total amount that you need the animal studies, as well as human, show that in a northern climate where you have winter weather and summer weather, the requirement for thyroid can be four times as high in the winter. I found year after year where I needed only half a grain of Armour thyroid, which would be ¼ of a tablet of cynoplus. I would need two whole grains of Armour or one whole tablet of cynoplus during the winter months. Animals pretty much are the same. So you have to be alert to changing according not only to the season but also to your activity level and diet. When I have to do yard work in warm weather I stop taking thyroid for a day or so, so that I can be more physically active and not produce too much heat.

PT (1:23:10)- Interesting. Rose has been hypothyroid for over 30 years on synthroid the whole time. She says; “ I’ve been, I’ve had numerous medical things happening in my body but I have no idea of who I can contact or get a hold of, any ideas of where I can start here? I’m confused.”

RP (1:23:40) Mary Shulmann years ago had a good international list but now they don’t have the patient comments anymore that help you guide yourself to which doctor you wanted. But if you ask around enough you might be able to find a doctor who recognizes that women in particular tend to have problems because estrogen interferes with the conversion of thyroxine to the active hormone T3. So women always are more dependent on the actual pre-formed T3, and very often get an anti-thyroid effect from over-accumulating the pure thyroxin because the liver is our main source of conversion to the active thyroid hormone and estrogen, the average woman will have a sluggish liver for the conversion, or for detoxifying alcohol for example. So women get drunk more easily than men because of the estrogen slow down of the liver. If a person is depending on the liver as their main source of T3, if they’ve had a thyroid gland removed, than their liver becomes the main source of T3.
(1:25:18) It just can’t do the work. Supplementing selenium or having seafood each week, the selenium allows our peripheral tissues to convert some of the T4 to T3, but if you have that problem of improper reaction to T4 then you really need a product that also contains T3.

PT (1:25:51)- Gloria says, ohoho this is interesting, “My dog has several lipomas and my natural vet suggested it is really a function of the liver I heard Dr. Peat a little while ago mention liver function and more fructose. What fructose could I give my dog?” Yeah, what fructose could I give my dog?

RP (1:26:17)- Dogs like fruit. We had a coker-spaniel that when the cherry tree had low hanging cherries she would get up on her hind legs and graze on them.

PT- So would you just cut up apples for the dog?

RP- Applesauce. More digestible.

PT- Vince says; “ This sounds counter intuitive, but please explain how sugar could help reverse type-2 diabetes?”

RP- I have articles on my website

PT (1:29:03) – Interesting. Mary says, she’s 70, “It seems the past few months I get several episodes of flushing and heat and my ears turn red, any idea what could be going on?”

RP – (1:29:20) – The same as with hot flashes. They can happen to men or women or young women. Anytime your metabolism is disturbed, your blood sugar falling, just a brief dip in your blood sugar will turn on things like nitric oxide production, causing vasodilation. Experimenters have cured nocturnal hot flashes, night sweats, by having them consume a cup of starch solution or eating a big cup of rice or ice cream or some carbohydrate at bed time. Just keeping your blood sugar up can momentarily stop the hot flashes, the main thing is getting your energy system efficient, making sure your thyroid and vitamin D and calcium intake are adequate.

PT (1:30:34) – Mhmm. Well I’ve been drinking a lot of Orange Juice thanks too you. My friend Anna Bergstrom, sometimes if I do my fasting blood sugar in the morning its dead on 85. Its not making me blood sugar crazy, and there’s a lot of sugar in orange juice, isn’t there?

RP- Good. Also potassium. The potassium itself fills in for insulin.

PT (1:31:02)- Do you think it’s worth it to go ahead and get the organic oranges and juice them yourself or the pasteurized, is it worth the effort? Any big difference for the body?

RP (1:31:17) – I was trying it for awhile but it was very hard to find organic oranges, consistently sweet. Sweetness is the over riding thing, you don’t want sour orange juice every morning.

PT - Not good

RP – No

PT- But you drink it throughout the day?

RP – Yeah all day intermittently, but it has to be reasonably sweet.

PT – Yeah, what is the real season for Oranges in Florida? Is it in the winter or summer?

RP - In a climate like that I think you have three orange seasons

PT – Do think there’s any concern of non-organic oranges of taking up chemicals such as glyphosate and stuff?

RP – Sure, but oranges that you’re suspicious of, not only wash but don’t get around the peeling. With organic oranges you can make marmalade of the peeling.

PT- Thanks so much for being here every month, we enjoy it. And what’s your latest newsletter on?

RP – It’s going to be on the same subjects. The bad adaptive processes that we’re exposed to constantly promoting aging, how it relates to inflammation and how to resist the pro-inflammatory forces.

PT- So I guess it could be a good argument, if we make it through all of this silliness going on in the world or whatever, that we’re all going to be stronger on the other end?

RP- The survivors yeah haha

PT- Thank you
 

Nemo

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Thank you, meatbag. Very helpful to have the transcript, which is great as usual.
 

Steve

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Thanks......so much time saved reading the interview rather than listening!
 

Perry Staltic

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PT (30:00)- How can we retain more Carbon Dioxide?

RP (30:04)- Moving to a 8,000 or 9,000 feet altitude. Leadville Colorado if you can adapt to it. The heart disease, cancer, and dementia rate goes down every thousand feet higher you live in altitude, the lower the cancer and heart disease.

PT (30:24)- Wow is that right? So just because more CO2 is retained?

RP (): Right

This is what I call sloppy science. Ray has no data for this, nor has he done research to support his point, yet he speaks confidantly. That's not how science works. It's also true that for every 1000 ft higher in altitude, populations and environmental toxins become sparser because industries and concomitant populations concentrate at lower altitudes. That's a huge confounding factor which makes it unwise for him to speak with such certainty.
 

Perry Staltic

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PT (): So when we exercise, we actually get rid of CO2, is that right?

RP (30:41): If it’s bad exercise.

PT (30:43): Bad exercise? What would be good exercise in your opinion?

RP (30:47): Anything that raises your body temperature it turns out that the good exercise that has prolonged effects is anything that raises your body temperature by muscle heat production and they’ve compared exercise to just warming the body and you get the same anti inflammatory anti heart disease, anti cancer effects and so on, just by getting your body temperature up which good exercise does.

This ignores the benefit of sustained aerobic exercise that actually remodels tissue with increased vascular penetration that enables better oxygenation of cells (respiration).
 

Nemo

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This is what I call sloppy science. Ray has no data for this, nor has he done research to support his point, yet he speaks confidantly. That's not how science works. It's also true that for every 1000 ft higher in altitude, populations and environmental toxins become sparser because industries and concomitant populations concentrate at lower altitudes. That's a huge confounding factor which makes it unwise for him to speak with such certainty.

Perry, there are a lot of studies on this issue. Go look at pubmed. Even google.

High altitude areas have lower rates of cancer, heart disease, and all the rest of it. Ray is on solid ground.
 

Perry Staltic

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Perry, there are a lot of studies on this issue. Go look at pubmed. Even google.

High altitude areas have lower rates of cancer, heart disease, and all the rest of it. Ray is on solid ground.

You obviously don't understand what confounding factors are. Correlation does not equal causation. I seriously doubt there is a worthwhile study with compelling evidence that life spans increase solely due to increased CO2 retention at higher altitudes as Ray suggests. If you think otherwise, show it to me.
 

Nemo

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You obviously don't understand what confounding factors are. Correlation does not equal causation. I seriously doubt there is a worthwhile study with compelling evidence that life spans increase solely due to increased CO2 retention at higher altitudes as Ray suggests. If you think otherwise, show it to me.

My degrees are in biochemistry from Harvard, where I went on full science scholarships because of my brain biochemistry research in high school. I certainly do understand what confounding factors are.

The CO2 at higher altitudes seems to be the critical factor. Go look up studies in pubmed for a while.

I will forgive you this slip because you usually put up interesting posts.
 

Perry Staltic

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My degrees are in biochemistry from Harvard, where I went on full science scholarships because of my brain biochemistry research in high school. I certainly do understand what confounding factors are.

The CO2 at higher altitudes seems to be the critical factor. Go look up studies in pubmed for a while.

I already told you I don't believe there is such a study, so why would I go look for it? Meanwhile you, who says there are many, can't produce one. The key elements are "worthwhile study with compelling evidence that life spans increase solely due to increased CO2 retention at higher altitudes."
 
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grithin

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And in your body when you have an excess of reduced Vitamin C taken in it finds Copper and Iron and that reacting couple will inevitably find some Polyunsaturated fat to make rancid instantly, so the combination of a trace of Copper or Iron plus Vitamin C, plus fat creates extreme lipid peroxidation

Might anyone elucidate the mechanism here?
 

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Buteyko Breathing - Bud Weiss, 2008-09-15

Ray Peat said:
For example living at a high altitude in Mexico city despite the pollution the incidence of asthma is drastically lower than it is in the lower altitude cities. That's undoubtedly because of the retention of carbon dioxide at high altitude where the oxygen pressure is lower.


Quick internet search "Mexico City" + "asthma".

Asthma prevalence in children living in north Mexico City and a comparison with other Latin American cities and world regions - PubMed (nih.gov)

Abstract
Reports of previous studies done without following the international guidelines in different cities of Mexico showed a decrease in asthma prevalence. The aim of this study was to determine the prevalence and severity of asthma symptoms in children and teenagers living in north Mexico City and compare them with those of other Latin American cities and world regions. The cross-sectional survey followed the protocol of the International Study of Asthma and Allergies in Childhood IIIb phase survey. The study population included children 6-7 years old and teenagers 13-14 years old from randomly selected primary and secondary schools. There were 1629 boys and 1582 girls in the group of 6- to 7-year-old children and 2039 boys and 1860 girls in the 13- to 14-year-old group. "Wheezing or whistling in the chest at any time in the past" was present in 19.2% (95% confidence interval [CI], 17.9, 20.6) of the children and in 17.0% (95% CI, 15.8, 18.1) of the teenagers; "wheezing or whistling in the chest in the last 12 months" was reported in 6.8% (95% CI, 5.9, 7.6) of the children and 9.9% (95% CI, 9.0, 10.8) of the teenagers; "asthma ever" was claimed in 4.5% (95% CI, 3.8, 5.2) of the children and 8.0% (95% CI, 7.1, 8.8) of the teenagers. These prevalences were low compared with other ISAAC Latin American surveys and intermediate in comparison with worldwide regional prevalences reported by ISAAC surveys. The prevalence of asthma is low in Mexico City in comparison with other surveyed locations, but the number of patients with asthma makes it an important issue for Mexican public health programs.


Air pollution in Mexico City - Wikipedia
 

Perry Staltic

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That could be due to any number of factors. Ray says it's "undoubtedly because of the retention of carbon dioxide at high altitude where the oxygen pressure is lower". Where's the evidence for that statement? Opinion does not equal science.
 

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Better yet, provide some research demonstrating this mechanism
Dr. Peat provides evidence for it with his explanation of the distilled water and ascorbic acid study, that he mentions right before making the statement. Did you read the whole thing?
 

Perry Staltic

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Dr. Peat provides evidence for it with his explanation of the distilled water and ascorbic acid study, that he mentions right before making the statement. Did you read the whole thing?

Dr. Peat talking about his conclusion or opinion on something he's read is not evidence. It's commentary. I need to see actual research.
 

grithin

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Dr. Peat talking about his conclusion or opinion on something he's read is not evidence. It's commentary. I need to see actual research.

Transcript:
USP vitamin C .... a gram of that in a liter of ultra-distilled water and found that in an apparatus to measure free radicals that it was producing from the Vitamin C and whatever trace metals contaminating the highly purified Vitamin C that in distilled water it was producing free radicals at the rate that a killing dose of x-rays would produce

This was actually too absurd for me to address, and why I asked for a mechanism regarding vitamin C in blood instead. How could @Vileplume take this as supporting evidence? It's like, there is no reading comprehension going on.

@Vileplume , if 1g of vitamin C + 1 liter of water = lethal dose of free radicals, comparable to lethal dose of x-ray, wouldn't you expect there to be a lot of deaths from people trying vitamin c flushes? Not to mention, have you tried finding this "study"?
 

gaze

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This is what I call sloppy science. Ray has no data for this, nor has he done research to support his point, yet he speaks confidantly. That's not how science works. It's also true that for every 1000 ft higher in altitude, populations and environmental toxins become sparser because industries and concomitant populations concentrate at lower altitudes. That's a huge confounding factor which makes it unwise for him to speak with such certainty.
That could be due to any number of factors. Ray says it's "undoubtedly because of the retention of carbon dioxide at high altitude where the oxygen pressure is lower". Where's the evidence for that statement? Opinion does not equal science.
Mexico city has tons and tons of environmental toxins, more than other low altitude cities.

There are tons of documented mechanisms, such as the "lactate paradox" that occurs as a result of the decreased oxygen at altitude which has wide ripple effect to improving the system

Altitude and Mortality

go through his sources on this if you want to find research:

J. Appl Physiol 1991 Apr;70(4):1720-30. .Metabolic and work efficiencies during exercise in Andean natives. Hochachka PW, Stanley C, Matheson GO, McKenzie DC, Allen PS, Parkhouse WS Department of Zoology, University of British Columbia, Vancouver, Canada. Maximum O2 and CO2 fluxes during exercise were less perturbed by hypoxia in Quechua natives from the Andes than in lowlanders. In exploring how this was achieved, we found that, for a given work rate, Quechua highlanders at 4,200 m accumulated substantially less lactate than lowlanders at sea level normoxia (approximately 5-7 vs. 10-14 mM) despite hypobaric hypoxia. This phenomenon, known as the lactate paradox, was entirely refractory to normoxia-hypoxia transitions. In lowlanders, the lactate paradox is an acclimation; however, in Quechuas, the lactate paradox is an expression of metabolic organization that did not deacclimate, at least over the 6-wk period of our study. Thus it was concluded that this metabolic organization is a developmentally or genetically fixed characteristic selected because of the efficiency advantage of aerobic metabolism (high ATP yield per mol of substrate metabolized) compared with anaerobic glycolysis. Measurements of respiratory quotient indicated preferential use of carbohydrate as fuel for muscle work, which is also advantageous in hypoxia because it maximizes the yield of ATP per mol of O2 consumed. Finally, minimizing the cost of muscle work was also reflected in energetic efficiency as classically defined (power output per metabolic power input); this was evident at all work rates but was most pronounced at submaximal work rates (efficiency approximately 1.5 times higher than in lowlander athletes). Because plots of power output vs. metabolic power input did not extrapolate to the origin, it was concluded 1) that exercise in both groups sustained a significant ATP expenditure not convertible to mechanical work but 2) that this expenditure was downregulated in Andean natives by thus far unexplained mechanisms.
 

Vileplume

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Transcript:


This was actually too absurd for me to address, and why I asked for a mechanism regarding vitamin C in blood instead. How could @Vileplume take this as supporting evidence? It's like, there is no reading comprehension going on.

@Vileplume , if 1g of vitamin C + 1 liter of water = lethal dose of free radicals, comparable to lethal dose of x-ray, wouldn't you expect there to be a lot of deaths from people trying vitamin c flushes? Not to mention, have you tried finding this "study"?
You make some good points about vitamin C flushes, which should create the same effect in our bodies but don’t. Perhaps the free radical production is different in our bodies than it is in a jar of distilled water.

While I can’t find the study Peat references, there’s evidence that ascorbic acid chelates and binds with copper and iron, leading to free radical production.


From the abstract:

“ Ascorbic acid and its metabolites, including the ascorbate anion and oxalate, have metal binding capacity and bind iron, copper and other metals. The biological roles of ascorbate as a vitamin are affected by metal complexation, in particular following binding with iron and copper. Ascorbate forms a complex with Fe3+ followed by reduction to Fe2+, which may potentiate free radical production.”
 

Perry Staltic

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J. Appl Physiol 1991 Apr;70(4):1720-30. .Metabolic and work efficiencies during exercise in Andean natives. Hochachka PW, Stanley C, Matheson GO, McKenzie DC, Allen PS, Parkhouse WS Department of Zoology, University of British Columbia, Vancouver, Canada. Maximum O2 and CO2 fluxes during exercise were less perturbed by hypoxia in Quechua natives from the Andes than in lowlanders. In exploring how this was achieved, we found that, for a given work rate, Quechua highlanders at 4,200 m accumulated substantially less lactate than lowlanders at sea level normoxia (approximately 5-7 vs. 10-14 mM) despite hypobaric hypoxia. This phenomenon, known as the lactate paradox, was entirely refractory to normoxia-hypoxia transitions. In lowlanders, the lactate paradox is an acclimation; however, in Quechuas, the lactate paradox is an expression of metabolic organization that did not deacclimate, at least over the 6-wk period of our study. Thus it was concluded that this metabolic organization is a developmentally or genetically fixed characteristic selected because of the efficiency advantage of aerobic metabolism (high ATP yield per mol of substrate metabolized) compared with anaerobic glycolysis. Measurements of respiratory quotient indicated preferential use of carbohydrate as fuel for muscle work, which is also advantageous in hypoxia because it maximizes the yield of ATP per mol of O2 consumed. Finally, minimizing the cost of muscle work was also reflected in energetic efficiency as classically defined (power output per metabolic power input); this was evident at all work rates but was most pronounced at submaximal work rates (efficiency approximately 1.5 times higher than in lowlander athletes). Because plots of power output vs. metabolic power input did not extrapolate to the origin, it was concluded 1) that exercise in both groups sustained a significant ATP expenditure not convertible to mechanical work but 2) that this expenditure was downregulated in Andean natives by thus far unexplained mechanisms.

That study addresses metabolic and work efficiencies during exercise. It's not rigorous science to equate those with increased lifespans. In fact it's not science at all.
 
EMF Mitigation - Flush Niacin - Big 5 Minerals

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