Hello, I have just signed up after reading the interesting stories and advice. I recently had an estrogen metabolite test and results showed high 16-OH E1, putting me at risk of breast cancer. Doctor said eat from the brassica family of vegetables twice a day as these vegetables help ward of cancer. I would love to know if anyone has any other information with a holistic/naturopathic view? I have Dr Peat's Progest E in the fridge, so I've started using it again. I believe that I am hypothyroid as I display all the symptoms, however tests come back normal. Please share your experience if you are in a similar position. Thanks!