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Carbon Dioxide Therapy In The Treatment Of Cellulite: An Audit Of Clinical Practice


Jan 6, 2015


The clinical practice of using carbon dioxide therapy for localized adiposities was audited over a 4-year period.

Patients receiving physical, dietary, or drug concurrent therapy were excluded from the audit. Original measurements in terms of mean ± standard error of the mean (SEM) were compared with those obtained after five sessions.

This series included 101 women who underwent abdominal therapy. Significant reduction (p < 0.05) in mean upper, mid, and lower abdomen circumference was experienced by all three age groups: respectively, 1.8 ± 0.5, 1.6 ± 0.4, and 2.1 ± 0.3 cm in the 20- to 29-year- old group, 1.6 ± 0.4, 2.3 ± 0.3, and 2.1 ± 0.3 cm in the 30- to 39-year-old group, and 2.0 ± 0.4, 2.5 ± 0.4, and 2.6 ± 0.4 cm in the 40- to 50-year-old group. For 57 women who underwent localized thigh therapy (27 in the 20- to 29-year-old group, 18 in the 30- to 39-year-old group, and 12 in the 40- to 50-year-old group), thigh circumference was significantly reduced in the right versus left thigh: respectively, 1.6 ± 0.3 versus 1.5 ± 0.2 cm, 1.1 ± 0.3 versus 1.1 ± 0.3 cm, 1.6 ± 0.3 versus 1.5 ± 0.4. Weight loss was significant for older women who underwent abdominal therapy: 1.3 ± 0.2 kg in the 30- to 39-year-old group (n = 43) and 1.3 ± 0.2 kg in the 40- to 50 year-old group (n = 29). Older women who underwent thigh therapy also recorded significant weight reduction: 0.9 ± 0.4 kg in the 30- to 39-year-old group (n = 18) and 1.6 ± 0.3 kg in the 40- to 50-year-old group (n = 12). The results for 10 men were not significant.

These results agree with those reported originally and demonstrate that carboxytherapy is safe and effective.


Feb 29, 2016
No serious complications from carboxytherapy have been reported, as evidenced in this audit. This is hardly surprising because CO2 is widely used in medicine as the mainstay of minimally invasive surgery. During laparoscopic procedures, CO2 is routinely used inside body cavities to provide a superb view and access for the ever-growing list of surgical procedures. Hypercapnia, which incidentally does not occur during carboxytherapy [7], is very well tolerated. The equipment used in this study is manufactured in Italy and approved by the European Community
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