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insulin sensitivity

  1. haidut

    DHT better (and safer) than testosterone for improving blood pressure, insulin levels

    A great human study on the beneficial effects of androgens for a variety of metabolic biomarkers associated with insulin resistance and diabetes II. The only gripe I have with this study is that they claim it was conducted with "healthy" men when in reality all men had low plasma total...
  2. A

    Insulin sensitivity

    Would healing liver and insulin sensitivity ensure fat loss? If so what are some of the best ways to increase insulin sensitivity?
  3. Hans

    The Truth On DHT: What The Research Shows

    Hi all, There is a common misconception that DHT causes prostate cancer, hair loss and what else not. I've been sifting through the research on what the effects of high DHT actually is and what happens if men take large doses of DHT for long periods of time. Here are my findings: The truth on...
  4. haidut

    Vitamin D Strikingly Therapeutic For Type II Diabetes

    Despite the ongoing assault against "ineffective" dietary supplements, the evidence in favor of them keeps piling on. One of the favorite targets of mainstream media is vitamin D, and multiple claims of "ineffectiveness" based on "meta" studies have come out in the last 5 years. Usually, this is...
  5. haidut

    Increased Fat Oxidation (FAO) Does Not Lead To Weight / Fat Loss

    The study below directly contradicts a mantra commonly repeated in nutrition circles - restrict glucose and increase fat oxidation in order to lose body fat. In fact, this idea is so ingrained into the minds of most people that I often get hate mail from people all over the world angrily...
  6. haidut

    Low-carb Diet Damages Blood Vessels In Humans

    I posted a study recently showing that low-carb diets increase risk for a potentially fatal heart rhythm disorder known as AFib. https://raypeatforum.com/community/threads/low-carb-diets-may-cause-lethal-heart-rhythm-disorder-afib.28169/ Now this new, also human, study below shows that even a...
  7. P

    “NO” To Autophagy: Fat Does The Trick For Diabetes

    “NO” to Autophagy: Fat Does the Trick for Diabetes During the progression from obesity to diabetes, a critical attribute is inability to maintain metabolic homeostasis under excessive energy and nutrient exposure, which triggers insulin resistance. Intensive research efforts have linked chronic...
  8. P

    Roles Of Interstitial Fluid PH In Diabetes Mellitus: Glycolysis And Mitochondrial Function

    Roles of interstitial fluid pH in diabetes mellitus: Glycolysis and mitochondrial function
  9. Hans

    Excess Iron Is Associated With Diabetes, Obesity And Metabolic Syndrome

    By this time we are all aware that iron should be kept low. In this study iron is involved in insulin resistance, inflammation and fat gain. Iron homeostasis: a new job for macrophages in adipose tissue? "men and women in the highest quintile of serum ferritin (Ft) levels – the primary...
  10. haidut

    Sterilizing The Gut Restores Insulin Sensitivity By Reducing Fatty Acid Oxidation

    I am posting this study just as an example of how important the role of endotoxin is in insulin resistance and diabetes. Similarly to the human study with aspirin, sterilizing the gut with antibiotics did not reduce the weight in the obese subjects (in this case mice). So, obesity may be a less...
  11. P

    Low Dose Doxycycline Decreases Systemic Inflammation And Improves Glycemic Control, Lipid Profiles,

    Low dose doxycycline decreases systemic inflammation and improves glycemic control, lipid profiles, and islet morphology and function in <i>db/db</i> mice Low dose doxycycline decreases systemic inflammation and improves glycemic control, lipid profiles, and islet morphology and function in...
  12. P

    Skeletal Muscle Phosphatidylcholine And Phosphatidylethanolamine Are Related To Insulin Sensitivity

    And the difference is big! 100% and 50% for each ,compared to subjects with higher insulin sensitivity. Egg yolks/milk and liver are rich source of these phospholipids. But yolks are the richest. Skeletal muscle phosphatidylcholine and phosphatidylethanolamine are related to insulin...
  13. P

    Betaine Lowers FFA And Improve Insulin Sensitivity And Adiponectine Level In High Fat Fed Animal

    Betaine improved adipose tissue function in mice fed a high-fat diet: a mechanism for hepatoprotective effect of betaine in nonalcoholic fatty liver disease Endoplasmic reticulum (ER) stress plays a critical role in adipose tissue dysfunction and insulin resistance in a variety of experimental...
  14. P

    Diabetogenic Impact Of Long-chain Omega-3 Fatty Acids On Pancreatic Beta-cell Function And The Regul

    Diabetogenic impact of long-chain omega-3 fatty acids on pancreatic beta-cell function and the regulation of endogenous glucose production. - PubMed - NCBI Abstract In healthy individuals, peripheral insulin resistance evoked by dietary saturated lipid can be accompanied by increased insulin...
  15. P

    Brain Insulin Resistance Identified As Possible New Link Between Alzheimer's Disease, Diabetes

    It says brains inability to burn glucose is responsible for Alzheimer's disease.caused by insulin's resistance in brain, and that probably mediated by inflammation. Brain Insulin Resistance Contributes to Cognitive Decline in Alzheimer's Disease – PR News...
  16. P

    Inflammation Mediates Free Fatty Acid-induced Insulin Resistance

    JNK and tumor necrosis factor-alpha mediate free fatty acid-induced insulin resistance in 3T3-L1 adipocytes. - PubMed - NCBI Lipid infusion and high fat feeding are established causes of systemic and adipose tissue insulin resistance. In this study, we treated 3T3-L1 adipocytes with a mixture...
  17. P

    DHT Levels Inversely Associated With Insulin Resistance Among Older Men

    Testosterone, Dihydrotestosterone, Sex Hormone Binding Globulin and Incident Diabetes among Older Men: the Cardiovascular Health Study. - PubMed - NCBI Abstract CONTEXT: Although sex hormone binding globulin (SHBG) and testosterone (T) have been inversely associated with risk of diabetes...
  18. P

    Iron Decreases Adiponectin - Phlebotomy(blood Donation),Manganese,zinc,vitamin D Increasing It

    Adipocyte iron regulates adiponectin and insulin sensitivity. - PubMed - NCBI Iron overload is associated with increased diabetes risk. We therefore investigated the effect of iron on adiponectin, an insulin-sensitizing adipokine that is decreased in diabetic patients. In humans, normal-range...
  19. haidut

    DHT Lowers Risk Of Diabetes In Older Males

    Most endocrinologists view DHT as an almost exclusively bad hormone. Aside from the its much publicized (and likely incorrect) role in prostate cancer and MPB, endocrinologists consider DHT as a causative agent in insulin resistance and even diabetes type II. Most of that misguided opinion...
  20. haidut

    Androsterone - A Potential Treatment For Insulin Resistance And Diabetes

    In another recent thread, I posted about androsterone's potent thyromimetic effects. Given the ability of thyroid hormone to improve insulin sensitivity and even reverse diabetes type II, it would not be surprising that androsterone would also exhibit such effects. And indeed, androsterone...
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