estradiol

  1. haidut

    Estrogen+PUFA Esters May Drive Obesity; Most Doctors Have Not Even Heard Of Them

    An unassailable dogma in endocrinology is that menopause is characterized by low estrogen levels. The fact that plasma levels are only indicative of ovarian activity is conveniently overlooked, as is the fact that fat tissue grows after menopause and fat is the primary source of estrone (estrone...
    • haidut
    • Thread
    • ester esters estradiol estrogen estrone insulin resistance obesity pufa
    • Replies: 9
    • Forum: Scientific Studies
  2. haidut

    The Carcinogenic And Estrogenic Effects Of PUFA

    Yet another study, which I decided to post because it is one of the few studies that directly points the finger at PUFA (and linoleic acid in particular - the nemesis of user @Travis) as the cause of breast, colon, prostate and other cancers. It also provides evidence for greatly increase serum...
    • haidut
    • Thread
    • breast cancer cancer colon cancer estradiol estrogen linoleic linoleic acid omega-6 prostate cancer pufa
    • Replies: 9
    • Forum: Scientific Studies
  3. haidut

    Estrogen Causes Asthma; Progesterone, T, DHT, And DHEA Are Protective

    Most of the forum members probably know that the incidence of "autoimmune" conditions is much higher in women then in men. This fact gets consistently ignored by doctors working in the field as a mere fluke, or due to "unknown hormonal interactions" which are nonetheless deemed not causative of...
    • haidut
    • Thread
    • asthma autoimmune cause estradiol estrogen histamine inflammation interleukin
    • Replies: 8
    • Forum: Scientific Studies
  4. haidut

    Even A Slight Increase In Estrogen Strongly Decreases DHEA Levels

    I posted a few studies in the past revealing that in old age (and menopause) the levels of pregnenolone, progesterone and DHEA declines, while that of cortisol and aldosterone stays the same or even increases. Pregnenolone, Progesterone And DHEA Drop, Cortisol Rises In Aging The decline in...
    • haidut
    • Thread
    • aging decline dhea dhea-s disease estradiol estrogen frailty menopause
    • Replies: 19
    • Forum: Scientific Studies
  5. haidut

    Estrogen Impairs Memory In Women

    There has been some evidence from rodent studies that estrogen and BDNF are antagonistic to each other as animals exposed to estrogen cannot remember very well. BDNF is akin to an anabolic steroid for the brain, and estrogen powerfully impairs its effects, especially in cases of traumatic brain...
    • haidut
    • Thread
    • alzheimer's bdnf dementia estradiol estrogen hrt inhibit memory women
    • Replies: 1
    • Forum: Scientific Studies
  6. haidut

    Pregnenolone, Progesterone And DHEA Drop, Cortisol Rises In Aging

    I posted a few times about the steroidal characteristics of aging. Many people think there is a drop in testosterone (T) in aging and that is what drives the frailty of aging both in men and women. However, numerous studies show that that total T does not decrease with aging. What does seem to...
    • haidut
    • Thread
    • adrenals aging cortisol dhea dht estradiol gonads pregnenolone progesterone steroidogenesis steroids testosterone
    • Replies: 29
    • Forum: Scientific Studies
  7. haidut

    The Antidepressant Mechanism Of Androsterone

    There is solid evidence that androgens have potent antidepressant effects in both sexes. However, the mechanism of action of that antidepressant effect has not been fully elucidated yet. On the other hand, it is also well known that chemicals that increase the levels of the so-called...
    • haidut
    • Thread
    • anabolic androgen androsterone antidepressant bdnf depression estradiol estrogen hpa stress
    • Replies: 20
    • Forum: Scientific Studies
  8. Drareg

    Study On The Binding Of Dihydrotestosterone, Testosterone And Oestradiol With Sex Hormone Binding Gl

    These binding affinitys bring up the question of what is happening when we supplement DHT? Does it free up testosterone and estrogen,will testosterone convert to estrogen even though DHT issue oozed to suppress this? The body has probably signalled no more DHT? Nothing here breaks down the free...
  9. P

    Estradiol Decreases Taurine Level By Reducing Cysteine Sulfinic Acid Decarboxylase Via The Estrogen

    Estradiol decreases taurine level by reducing cysteine sulfinic acid decarboxylase via the estrogen receptor-α in female mice liver. - PubMed - NCBI Cysteine sulfinic acid decarboxylase (CSAD) and cysteine dioxygenase (CDO) are two rate-limiting enzymes in taurine de novo synthesis, and their...
  10. haidut

    Hypothyroidism Dramatically Increases Estrogen Synthesis

    I posted a study some time ago showing the effects of thyroid hormone on synthesis/metabolism of various steroids. Hyperthyroidism increased androgen production several-fold, but the effects on estrogen synthesis were less clear. This study shows that hypothyroidism increases estrogen...
    • haidut
    • Thread
    • estradiol estrogen hypothyroidism increases normalizes synthesis t3 upregulates
    • Replies: 13
    • Forum: Scientific Studies
  11. haidut

    Infertility In Men Linked To High Estrogen

    Not really surprising but some "studied" have tried to paint a link between increased androgens and infertility, so I thought this would be good post here as a counter-perspective. Increased oestradiol level in seminal plasma in infertile men. - PubMed - NCBI "...Seminal hormonal patterns in...
  12. haidut

    Estrogen Potentiates "addiction" Through The Endocannabinoid (CB1) Receptor

    Please do not take this as an attack on weed. I found this by accident while researching the similarities between estrogen and cocaine, which Ray has written about before. So, the study is really about estrogen and cocaine "addiction". I think the key takeaway is that the endocannabinoid...
    • haidut
    • Thread
    • addiction cannabinoid cb1 estradiol estrogen potentiates stress
    • Replies: 19
    • Forum: Scientific Studies
  13. haidut

    Aspirin Lowers Estrogen Levels / Load / Burden

    It is known that aspirin can inhibit the activation of the enzyme aromatase, which is activates by things like stress and prostaglandins. However, studies showing direct effects of aspirin on estrogenic burden / load in humans are lacking. Speaking of estrogenic burden / load, as I mentioned in...
    • haidut
    • Thread
    • aspirin e1 e1s e2 estradiol estrogen estrone estrone sulfate testosterone
    • Replies: 15
    • Forum: Scientific Studies
  14. P

    Aromatase Inhibition Significanty Enhance Nerve Regeneration

    Sex differences in the effectiveness of treadmill training in enhancing axon regeneration in injured peripheral nerves. - PubMed - NCBI Exercise in the form of daily treadmill training results in significant enhancement of axon regeneration following peripheral nerve injury. Because androgens...
  15. P

    Effects Of Estrogen Versus Estrogen And Progesterone On Cortisol And Interleukin-6

    http://www.maturitas.org/article/S0378-5122%2808%2900258-2/abstract Abstract Objectives The purpose of this study was to compare the effects of 3 months of estrogen replacement therapy, estrogen plus progesterone replacement therapy and a placebo, on the resting cortisol and interleukin-6...
  16. P

    Estradiol Inhibits Hyaluronic Acid Synthase 1 Expression In Human Vascular Smooth Muscle Cells

    Estradiol inhibits hyaluronic acid synthase 1 expression in human vascular smooth muscle cells. - PubMed - NCBI Epidemiological and clinical data suggest that estrogen retards the progression of atherosclerosis. This study aims to elucidate whether the phenotypic regulation of human vascular...
  17. haidut

    Estradiol In Birth Control Pills Causes Seizures

    After 5 decades of public lies that estrogen-based birth control pills are safe, this study now finally says what Ray has been saying for years - estrogen is a brain excitant and causes seizures. And not only does it cause seizures but it causes the type that lead to brain damage. I am not sure...
    • haidut
    • Thread
    • birth control brain damage estradiol estrogen pils seizures uncontrolled
    • Replies: 2
    • Forum: Scientific Studies
  18. P

    The Role Of Dopamine In Methylene Blue-mediated Inhibition Of Estradiol Benzoate-induced Anterior Pi

    The role of dopamine in methylene blue-mediated inhibition of estradiol benzoate-induced anterior pituitary hyperplasia in rats. - PubMed - NCBI Abstract Recently, we demonstrated that methylene blue partially inhibited estradiol-benzoate-induced anterior pituitary hyperplasia in rats. Since...
  19. haidut

    Estrogen (estradiol) Promotes Autoimmunity

    If there is any doubt in anybody's mind about the role of estrogen as a cause of autoimmune conditions I hope that his will clarify the situation some more. The excerpt below is from the study on adrenals and Alzheimers I posted today but I thought that this excerpt deserves its own thread given...
    • haidut
    • Thread
    • aging alzheimer's autoimmune autoimmunity estradiol estrogen immunodeficiency
    • Replies: 6
    • Forum: Scientific Studies
  20. S

    Estradiol And Testosterone Have Opposite Effects On Microtubule Polymerization

    Estradiol and testosterone have opposite effects on microtubule polymerization. Click Orch OR in the signature below for an interesting hypothesis about microtubules and consciousness.
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