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  1. tastyfood

    Is summing estradiol, estrone, and estriol the right way to calculate total estrogen levels in serum?

    I was looking at some old estrogen tests I had done, and noticed the the total estrogens doesn't match with the sum of estradiol and estrone, even if they are measured in the same units. Does anyone know if the total estrogens is supposed to be the arithmetic sum of estradiol, estrone, and...
  2. Hans

    Topical DHEA can suppress you (and increase testosterone)!

  3. Hans

    The Unexpected Downsides of Resveratrol as an Aromatase Inhibitor

  4. haidut

    Estrogen causes prostate fibrosis (cancer?), DHT prevents/treats it

    Slowly, but surely, the myth of the "evil" dihydrotestosterone (DHT) and the "beneficial" estrogen, when it comes to prostate health, is going the way of the dodo. In fact, people I know who work in research circles say that the "androgen hypothesis" in prostate cancer is no longer being taken...
  5. Hans

    Androstenedione for maximizing testosterone; good or no?

    https://men-elite.com/2022/11/29/androstenedione-for-maximizing-testosterone-good-or-no/ --------------- TL: DR Androstenedione: Increases T very mildly and only short term, before it causes suppression and enhances testosterone excretion. Increases estrogens to a great extent and for longer...
  6. Hans

    Optimize your testosterone-to-estrogen ratio with thyroid

  7. BlackMolasses

    Could progesterone correct a problem of insomnia in a postmenopausal woman?

    My mother is in menopause and suffers from insomnia, she has obvious signs of too high levels of estradiol (hot flashes, aggressiveness and emotional instability, insomnia?...). Could progesterone help counter balance the problems of menopause by antagonizing estradiol? Would it have any harmful...
  8. haidut

    DHT blocks, androgen antagonists promote breast cancer

    The first claim of the title is already well-known to my readers and to clinical practice. DHT was clinically used back in the middle of the 20th century as a treatment for breast cancer, and the synthetic androgen Drostanolone (Masteron), which still retains its approval by FDA for breast...
  9. Gûs80

    Could aromatase inhibitors be useful in autoimmune diseases?

    Dr Ray Peat mentions in some articles that the cause of autoimmune diseases is high estrogen. Considering this, has anyone seen benefits from using a pharmaceutical aromatase inhibitor? I have a positive ANA marker for Lupus/Sjogren's, and even though it's low, I have several of the symptoms of...
  10. haidut

    Estrogen associated with arterial stiffness in women

    Blood pressure rises with age, and most people over the age of 50 are on some type of blood pressure controlling medication. It is well-known that blood vessels calcify/stiffen with age and that such stiffness is what leads to increased blood pressure - i.e. the inability of vessels to...
  11. haidut

    Low testosterone (T) and/or high estrogen/T ratio predict COVID-19 mortality

    So, there we have it - yet another shameless lie exposed. After claiming completely evidence-free since the beginning of 2020 that high androgen levels are detrimental to males when it comes to COVID-19, mainstream medicine now gets to see its lies/incompetence exposed. Those shameless lies...
  12. JamesGatz

    Leave the Receipts at the store - Receipt Paper is LOADED with ESTROGENS

    If most of you haven't noticed from your own experience touching paper receipts - it seems to give a really big boost to estradiol - especially for users working cashier jobs I would advice having thick gloves or metal clamps to touch this kind of stuff - really not good handling it all day...
  13. haidut

    Even "non-carcinogenic" estrogens can cause cancer

    I know, the title is a "paradox", but this is truly what the article discusses. By now, we already know that the word "paradox" in science is just a euphemism for idotism and/or fraud. Apparently, mainstream medicine has managed to convinced the public somehow that there are carcinogenic and...
  14. shine

    Social isolation stimulates hippocampal estradiol synthesis

    "17β-Estradiol is synthesized de novo in the rat hippocampus. However, the regulatory mechanism of hippocampal estradiol synthesis has remained unclear. We investigated the effects of social isolation on rat hippocampal estradiol synthesis. Rats were divided into two groups: social isolation and...
  15. Lokzo

    Elevated Serum Estradiol Levels May Impair Erectile Function

    Erectile dysfunction attributable to testosterone deficiency is less common in young males, and the effect of estradiol on erectile function in eugonadal young males is unclear. We analyzed data from 195 male participants, including 143 eugonadal patients with erectile dysfunction and 52...
  16. haidut

    Estrogen Can Both Cause And Exacerbate Lupus

    A quick post as a response to a recent argument I had over email with an endocrinologist who follows me on Twitter. His claim was that the causes of Lupus are currently unknown but are likely "multifactorial" and me ascribing such causes to "isolated peculiarities" such as endotoxin (LPS) or...
  17. haidut

    Estrogen Lowers T, DHT, And Fertility; Inhibits 5α-Reductase (5-AR)

    I am posting this study below as a response to numerous angry emails I have been getting over the years. People sending me those emails just cannot accept the idea that estrogen can be detrimental for males (and females as well), and that estrogen levels are directly antagonistic to the male...
  18. haidut

    Aromatase Inhibitor (AI) + DHT Combo May Reverse Kidney Disease (CKD)

    A truly great study for a number of reasons. First, it cites extensive evidence that male patients with diabetes (both types) have low androgens and high estrogen (estradiol). The association between this endocrine abnormality and the severity of diabetes is apparently quite strong, yet it is...
  19. haidut

    Estrogen Directly Causes Polycystic Ovary Syndrome (PCOS)

    The worldwide rates of PCOS are skyrocketing, and have more than doubled over the last 10 years. Currently, about 12% of women in child-bearing age living in "developed" countries have PCOS and as a result struggle with infertility, diabetes, CVD, acne, bone issues, and even cancer. The fact...
  20. B

    Anti-Peat E2 Is Not The Problem

    “. E2 promotes energy homeostasis, improves body fat distribution, ameliorates insulin resistance (or enhances insulin sensitivity), improves β-cell function, and reduces inflammation. “ The Role of Estrogens in Control of Energy Balance and Glucose Homeostasis Aromatase activity and bone...