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diabetes

  1. C

    Profound linear effect of Hesperidin in diabetes & ulcer / wound healing (& protection against toxic heavy metals) (+youth restoration)

    Hesperidin enhances angiogenesis via modulating expression of growth and inflammatory factor in diabetic foot ulcer in rats Rats with induced diabetes & ulcers were given Hesperidin orally, at does 10mg/kg - 80mg/kg . Group I = non-diabetic non-wounded controls Group II = non-diabetic wounded...
    • cs3000
    • Thread
    • diabetes heavy metals hesperidin mitochondria toxic metals ulcer wound healing
    • Replies: 12
    • Forum: Scientific Studies
  2. haidut

    Vitamin D can reverse peripheral neuropathy and demyelination

    Some great news for patients with diabetes and/or multiple sclerosis (MS). The former is well-known to cause peripheral neuropathy (PN) and the latter's defining characteristics is a progressive demyelination, which leads to both central and peripheral symptoms, including pain, burning, muscle...
    • haidut
    • Thread
    • cholecalciferol demyelination diabetes multiple sclerosis myelin peripheral neuropathy vitamin d
    • Replies: 0
    • Forum: Scientific Studies
  3. haidut

    Glycine may prevent/treat diabetic neuropathy

    A very interesting study, which adds more evidence in favor of the recent hypothesis that glycine (just as taurine) is in fact an essential amino acid. Namely, despite our ability to synthesize glycine, as needed, from the truly essential amino acids, its absence in the diet leads to pathologies...
    • haidut
    • Thread
    • diabetes essential glycine inflammation insulin neuropathy serine
    • Replies: 2
    • Forum: Scientific Studies
  4. Limon9

    Coffee Diterpenes Have A Metformin-Like Anti-Diabetic Action

    My previous post highlighted the pathological mTOR-mediated aerobic glycolysis caused by endotoxin, so I thought it should be balanced with an example of glycolysis-boosting when oxidative phosphorylation is unimpaired. The experiment looked both in vitro and in vivo at the effects of kahweol, a...
    • Limon9
    • Thread
    • ampk coffee diabetes fatty acid oxidation glucose metabolism glycolysis kahweol metformin
    • Replies: 3
    • Forum: Scientific Studies
  5. rothko

    Help me analyze relative's bloodwork

    33 yo male, before breakfast -- has issue with stress and anxiety. depression/slightly bipolar.
  6. haidut

    PUFA metabolite (prostaglandin) promotes lipolysis / fibrosis, causes obesity / diabetes

    Just in case there are still doubts out there about just how detrimental PUFA is to our health, here is a study showing that just one of PUFA's "normal" metabolites (i.e. enzymatically derived, instead of through peroxidation) is sufficient to elevate lipolysis, and that effect alone is enough...
    • haidut
    • Thread
    • aspirin cox diabetes fibrosis lipolysis obesity pge2 prostaglandin pufa
    • Replies: 1
    • Forum: Scientific Studies
  7. haidut

    Blocking serotonin, promoting dopamine may reverse cardiovascular disease (CVD)

    The claim in the title stems from the fact that bromocriptine - the drug used in the study below - is an approximate 5-HT antagonist while also being full agonist on several dopamine receptors. IMO, the study is a monumental success since CVD is largely considered a progressive condition, for...
    • haidut
    • Thread
    • blood pressure bromocriptine calcification cvd diabetes dopamine serotonin stiffness
    • Replies: 3
    • Forum: Scientific Studies
  8. haidut

    Diabetes, Alzheimer's, cancer are bioenergetic diseases; PUFA may be the cause

    The bad news for PUFA (in this case linoleic acid) just keep piling on. At this point, there is hardly a chronic condition out there that has not been linked to elevated PUFA and/or their peroxidation products. The first study below makes the argument that PUFA peroxidation byproducts (created...
    • haidut
    • Thread
    • 4-hydroxynonenal alzheimer cancer diabetes mitochondria oxphos pufa ros
    • Replies: 1
    • Forum: Scientific Studies
  9. haidut

    Endotoxin (LPS) may drive kidney damage in diabetes type II

    Not much of a news, but I like adding to the, already big, pile of evidence that endotoxin/LPS is a major causal factor in virtually all chronic conditions that continue to mystify medicine. Since the study below mentions the compromised intestinal barrier in diabetes patients, interventions...
    • haidut
    • Thread
    • ckd diabetes endotoxin gut barrier kidney damage lps microalbumineria tlr4
    • Replies: 3
    • Forum: Scientific Studies
  10. youngsinatra

    Mastering Diabetes Program

    Did anyone of you heard of the „Mastering Diabetes“ program? It seems pretty aligned with the idea of the glucose / fatty acids substrate competition. (Randle effect) I am following a similar diet even though I additionally eat quite a lot of very lean animal meat (like chicken breast) for...
  11. haidut

    Lifestyle, not age, rules cognitive function...

    ...whether you are 18 or 80. Yes, I know it is hard to believe this statement but that is the conclusion of the study after examining the link between lifestyle (and environment) and cognitive function in a group of people with ages spanning the 18-89 years interval. The conclusion of the study...
    • haidut
    • Thread
    • aging brain cognition dementia diabetes education lifestyle smoking
    • Replies: 15
    • Forum: Scientific Studies
  12. Katelove

    Blood Glucose - High Carb/Low Fat

    I have been doing a high carb/low fat diet to address my diabetes. I was testing at a 170 fasting blood glucose for a while and then I added sugar and fruit for about a month. I didn't test during this time. When I tested again I was at a 500 post prandial. My fasting was 330. I have given up...
    • Katelove
    • Thread
    • blood sugar diabetes high carb low fat
    • Replies: 81
    • Forum: Blood Sugar
  13. haidut

    PUFA metabolites may trigger diabetes type I

    Type I diabetes is known as an autoimmune condition. Namely, for some "unknown" reason(s) the beta-cells of the pancreas get attacked by the immune system and over time this leads to their destruction and inability to produce insulin. Of course, no such thing as an "autoimmune" disease exists...
    • haidut
    • Thread
    • 12/15lox beta-cells diabetes inflammation leukotriene lipoxygenase pancreas pufa
    • Replies: 3
    • Forum: Scientific Studies
  14. haidut

    Vitamin B1 as a potential treatment for Alzheimer's Disease (AD)

    After decades of denial that AD is a metabolic condition, Big Pharma and Big Govt, are silently doing an 180-degree turn by secretly funding university clinical trials for metabolic interventions in that disease. The study below will evaluate the effects of benfotiamine - a lipophilic analog of...
    • haidut
    • Thread
    • alzheimer benfotiamine dementia diabetes glucose oxphos thiamine
    • Replies: 27
    • Forum: Scientific Studies
  15. AlphaCog

    Shinrin-yoku (forest-air bathing and walking) effectively decreases blood glucose levels in diabetic patients

    Abstract The influence of "shinrin-yoku" (forest-air bathing and walking) on blood glucose levels in diabetic patients was examined. Eighty-seven (29 male and 58 female) non-insulin-dependent diabetic patients [61 (SEM 1) years old] participated in the present study. Shinrin-yoku was performed...
    • AlphaCog
    • Thread
    • air bathing blood glucose diabetes forest-air insulin sensitivity nature shinrin-yoku
    • Replies: 11
    • Forum: Mind, Sleep, Stress
  16. haidut

    Malnutrition (fasting) or protein deficiency sufficient to cause diabetes

    Yet another study that should give a pause to all health care providers who push their patients to lose weight at any cost - i.e. "lower is always better", when it comes to BMI, as the dogma goes. Well, apparently not, according to the study below. The even more astounding fact is that it looks...
    • haidut
    • Thread
    • bmi caloric restriction diabetes fasting malnutrition protein deficiency zinc
    • Replies: 3
    • Forum: Scientific Studies
  17. haidut

    SHBG may be a good test for liver (metabolic) health

    A very good study, which probably runs counter to the "mantra" most bodybuilders adhere to - i.e. they would say one must keep their SHBG low in order to increase levels of "free" steroids since, the claim goes, only free steroids are active and capable of influencing cells. If SHBG is high, the...
    • haidut
    • Thread
    • biomarker diabetes glucose oxidation insulin liver metabolism shbg
    • Replies: 1
    • Forum: Scientific Studies
  18. xeliex

    Full blown metabolic syndrome and diabetes

    My 40 year old friend just got his blood tests back due to c/o polydipsia and polyuria. His blood glucose came back over 250 mg/dL and his glycosylated hemoglobin 12%! His lipids where terribly high too - high cholesterol, high triglycerides. He is on synthroid and has been for a long time -...
  19. haidut

    PUFA cause obesity, diabetes, autism, Alzheimer's disease, anxiety, and depression

    The title is an actual quote from the article, so there is no editorializing on my part and it speaks volumes about how the authors feel about their findings. In addition, opposite effects were found for saturated fats, in this case coconut oil, which leads the authors to once again remind...
    • haidut
    • Thread
    • alzheimer autism depression diabetes metabolism oxphos pufa soybean oil
    • Replies: 3
    • Forum: Scientific Studies
  20. haidut

    Endotoxin (LPS) drives obesity, diabetes and CVD in young people

    It looks like medicine is starting to change course on its attitude to endotoxin (LPS). After claiming that LPS is not an issue at all for any human with a functioning liver, a number of high profile studies have come out recently demonstrating chronic endotoxemia (even low-grade) is a causal...
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