calcification

  1. AlphaCog

    Propionate Microbiome

    A human gut microbial gene catalogue established by metagenomic sequencing Gut bacteria use mostly fermentation to generate energy, converting sugars, in part, to short-chain fatty acid, that are used by the host as energy source. Acetate is important for muscle, heart and brain cells...
    • AlphaCog
    • Thread
    • barley calcification carbon dioxide gastrointestinal transit time oat bran propionic acid salmonella scfa short chain fatty acid succinic acid
    • Replies: 0
    • Forum: Digestion, Gut Flora
  2. haidut

    The fraud unravels - statins cause, not prevent heart disease (CVD)

    While the news that the statin fraud is finally being exposed is certainly good, it is sad that it took so many decades to admit to something so biochemically obvious. Namely, since statins interfere with the synthesis of mevalonic acid, as a consequence they also inhibit the synthesis of the...
    • haidut
    • Thread
    • atp calcification cholesterol coq10 cvd myopathy statin vitamin k
    • Replies: 39
    • Forum: Scientific Studies
  3. cs3000

    Sodium Bicarbonate for issues with calcification from vitamin D? - carbon dioxide

    https://pubmed.ncbi.nlm.nih.gov/26538435/ conflicting study outside of this model: https://pubmed.ncbi.nlm.nih.gov/19809998/ conflicting to that one: From Ray peats newsletter: https://archive.org/details/mega-master-ray-newsletter/page/n163/mode/2up?q=bicarbonate I think 2g of sodium...
    • cs3000
    • Thread
    • baking soda calcification carbon dioxide hypercalcemia sodium bicarbonate vitamin d
    • Replies: 2
    • Forum: Scientific Studies
  4. Apple

    Takuo Fujita (Calcium Paradox) passed away on November 8, 2022, (16 days before Ray Peat)

    Takuo Fujita, MD, PhD (February 10, 1929 to November 8, 2022) https://link.springer.com/article/10.1007/s00774-023-01399-x Ray Peat cited T. Fujita in some of his articles regarding calcium and PTH. He developed a theory which he called the ‘Calcium Paradox’, that is, the contradiction between...
    • Apple
    • Thread
    • calcification calcium calcium paradox parathyroid pth
    • Replies: 73
    • Forum: Ray Peat Topics
  5. haidut

    Declining DHT in aging linked to cardiovascular disease (CVD)

    Yet another study demonstrating that the "villain of all males around the world" - the dastardly androgen dihydrotestosterone (DHT) - actually is, in all likelihood, beneficial for males, at least when it comes to their cardiovascular health. However, since CVD is one of the risk factors for...
    • haidut
    • Thread
    • androgen calcification cvd dht dihydrotestosterone inflammation stiffness vascular
    • Replies: 3
    • Forum: Scientific Studies
  6. haidut

    Blocking serotonin, promoting dopamine may reverse cardiovascular disease (CVD)

    The claim in the title stems from the fact that bromocriptine - the drug used in the study below - is an approximate 5-HT antagonist while also being full agonist on several dopamine receptors. IMO, the study is a monumental success since CVD is largely considered a progressive condition, for...
    • haidut
    • Thread
    • blood pressure bromocriptine calcification cvd diabetes dopamine serotonin stiffness
    • Replies: 4
    • Forum: Scientific Studies
  7. Mauritio

    Carbonic anhydrase II as a biomarker for vascular calcification

    "Several other synthetic estrogenic substances, ethynylestradiol, lindane, PCBs, cause eggshell thinning, partly by altering carbonic anhydrase activity (Holm, et al, 2006). Estrogen and serotonin activate carbonic anhydrase in some tissues, progesterone tends to inhibit it." -Ray Peat Peat has...
    • Mauritio
    • Thread
    • acetazolamide aspirin calcification carbonic anhydrase carbonic anhydrase inhibitor co2 vascular calcification
    • Replies: 3
    • Forum: Science
  8. haidut

    "Endurance" exercise ages the vascular system of males by more than a decade

    A very interesting study, though I don't really agree with its findings that while "endurance" (in this case running) exercise damages male vascular system it is beneficial for the female one. The majority of intervention studies that looked at both sexes, across all age groups found that...
    • haidut
    • Thread
    • aging calcification cortisol cvd endurance exercise running vascular
    • Replies: 23
    • Forum: Scientific Studies
  9. UG Krishnamurti

    Dietary Ca or Ca/P during inflammation will increase calcification and microcalcification?

    When I am in inflamed state I always felt extremely worse if I drink milk for example. The symptoms I experience were intestinal bleeding (I have Crohn's), extreme scalp hardness, psoriasis getting worse, fatigue, cramping etc. Even just drinking plain mineral water higher in calcium created...
  10. UG Krishnamurti

    Wishing this man the best but what can we learn from looking at his markers?

    "How the f*ck did I have three blocked arteries?? I fasted, ate low carb, cut seed oils, did cardio and weights at least 5x a week. End result…. My widow maker was 95% blocked?? thank the Lord I just happened to go to cardiologist after iwatch reported afib" LINK TO THE TWITTER POST Take a...
    • UG Krishnamurti
    • Thread
    • atherosclerosis calcification cardiovascular cvd k2 vdr vitamin d vitamin k
    • Replies: 86
    • Forum: Diet
  11. UG Krishnamurti

    VIT K2 MK-4 increased calcification/stiffness?

    While VIT K2 MK-4 [45mg] helped me with eczema and psoriasis [which maybe prove that this particular skin issues are tightly related to the blood vessels] it caused me to have symptoms of aortic valve calcification/myocarditis. Really badly. Extreme chest tightening, short cough, shallow...
    • UG Krishnamurti
    • Thread
    • aortic valve calcification arterial stiffness calcification stiffness vit k
    • Replies: 30
    • Forum: K
  12. haidut

    Exercise causes (and worsens) arterial calcification

    A great new study sent to me by one of my readers. It will more than likely cause a lot of controversy, despite its findings having a very simple explanation. Namely, chronic exercise increases baseline cortisol and over time, cortisol (acting through the aldosterone/mineralocorticoid receptor)...
    • haidut
    • Thread
    • aldosterone calcification chronic cortisol exercise soft-tissue calcification stress
    • Replies: 33
    • Forum: Scientific Studies
  13. S

    Cypro Works Like Vitamin K2 For A Better Jawline?

    Hi, everyone. I read on the forum about cypro having a vitamin K2-like effect on calcification, and I saw reports of people who took vitamin k2 who got, through the anti-calcification effect, a larger jaw. My question is, does cypro have the same effect? Could someone who used it report?
    • southcesar
    • Thread
    • calcification cyproheptadine jaw vitamin k vitamin k2
    • Replies: 11
    • Forum: Cyproheptadine
  14. haidut

    Vitamin K May Help Reduce Arterial Stiffness & Improve Blood Pressure

    For those of my readers who don't know, vitamin K is a prescription drug in many countries for treating/preventing osteoporosis, blood pressure, liver disease, neurological disorders, cancer, etc. Japan is where this remarkable substance enjoys perhaps the most prestige as an actual drug for...
    • haidut
    • Thread
    • arterial stiffness calcification cvd hypertension menaquinone menatetrenone mk-4 prevent reduce treat vitamin k
    • Replies: 9
    • Forum: Scientific Studies
  15. haidut

    Vitamin E, Anabolic / Catatoxic Steroids, Egg Yolks Stop Soft Tissue Calcification And (maybe) Even

    A great series of studies performed in the 1960s, with Hans Selye spearheading most of the investigations. It is amazing how much was known about human disease and aging, and how much of that knowledge has been so thoroughly forgotten to the point that doctors nowadays have never even heard of...
    • haidut
    • Thread
    • aging anacalciphylaxis calcification calcinosis calciphylaxis prevent progeria reverse soft-tissue calcification testosterone tocopherol vitamin e
    • Replies: 29
    • Forum: Scientific Studies
  16. haidut

    Vitamin K Important For Eye Health Too

    In addition to its role in bone, brain, and endocrine health now we can add eyes to the list of tissues/organs that may benefit from vitamin K as well. Unfortunately, most studies are still trying to study vitamin K from the point of view of osteocalcin and carboxylation, which only explains a...
    • haidut
    • Thread
    • beneficial calcification eyes health matrix gla protein menaquinone mgp mk-4 ocular promote vitamin k vitamin k1 vitamin k2
    • Replies: 14
    • Forum: Scientific Studies
  17. whatever

    Thiosulfate Promotes Hair Growth

    Abstract The present study describes the hair growth-promoting effects of sodium thiosulfate (STS), a widely used compound, in mice. STS accelerated hair growth in the "telogen model", suggesting that it stimulates telogen hair follicles to reenter the anagen phase of hairgrowth. In the same...
  18. Renaiscience_Man

    High Dose Aspirin And Vitamin K2 May Be The Key To Eradicate ''incurable'' Bacterial Infections Whic

    Nanobacteria: An alternative mechanism for pathogenic intra- and extracellular calcification and stone formation
  19. haidut

    Cyproheptadine Prevents / Reverses Soft Tissue Calcification

    Human equivalent dose was about 12mg daily, duration was just 4 days. Cyproheptadine prevented AND reversed soft tissue calcification by acting as an anti-heparin agent, which is similar to what vitamin K2 does. http://www.ncbi.nlm.nih.gov/pubmed/14324165 "...In the rat, cyproheptadine...
  20. P

    Reversed Warfarin Induced Arterial Calcification By Vitamin K Supplement And K1 As Effective As K2

    http://www.ncbi.nlm.nih.gov/pubmed/17138823/ Arterial calcification (AC) is generally regarded as an independent risk factor for cardiovascular morbidity and mortality. Matrix Gla protein (MGP) is a potent inhibitor of AC, and its activity depends on vitamin K (VK). In rats, inactivation of...
    • paymanz
    • Thread
    • calcification matrix gla protein statins vitamin k vitamin k1 vitamin k2 warfarin
    • Replies: 7
    • Forum: Scientific Studies
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