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Yet another study demonstrating that the "villain of all males around the world" - the dastardly androgen dihydrotestosterone (DHT) - actually is, in all likelihood, beneficial for males, at least when it comes to their cardiovascular health. However, since CVD is one of the risk factors for...
The claim in the title stems from the fact that bromocriptine - the drug used in the study below - is an approximate 5-HT antagonist while also being full agonist on several dopamine receptors. IMO, the study is a monumental success since CVD is largely considered a progressive condition, for...
"Several other synthetic estrogenic substances, ethynylestradiol, lindane, PCBs, cause eggshell thinning, partly by altering carbonic anhydrase activity (Holm, et al, 2006). Estrogen and serotonin activate carbonic anhydrase in some tissues, progesterone tends to inhibit it."
-Ray Peat
Peat has...
A very interesting study, though I don't really agree with its findings that while "endurance" (in this case running) exercise damages male vascular system it is beneficial for the female one. The majority of intervention studies that looked at both sexes, across all age groups found that...
When I am in inflamed state I always felt extremely worse if I drink milk for example. The symptoms I experience were intestinal bleeding (I have Crohn's), extreme scalp hardness, psoriasis getting worse, fatigue, cramping etc. Even just drinking plain mineral water higher in calcium created...
"How the f*ck did I have three blocked arteries?? I fasted, ate low carb, cut seed oils, did cardio and weights at least 5x a week. End result…. My widow maker was 95% blocked?? thank the Lord I just happened to go to cardiologist after iwatch reported afib"
LINK TO THE TWITTER POST
Take a...
While VIT K2 MK-4 [45mg] helped me with eczema and psoriasis [which maybe prove that this particular skin issues are tightly related to the blood vessels] it caused me to have symptoms of aortic valve calcification/myocarditis. Really badly.
Extreme chest tightening, short cough, shallow...
A great new study sent to me by one of my readers. It will more than likely cause a lot of controversy, despite its findings having a very simple explanation. Namely, chronic exercise increases baseline cortisol and over time, cortisol (acting through the aldosterone/mineralocorticoid receptor)...
Hi, everyone. I read on the forum about cypro having a vitamin K2-like effect on calcification, and I saw reports of people who took vitamin k2 who got, through the anti-calcification effect, a larger jaw. My question is, does cypro have the same effect? Could someone who used it report?
For those of my readers who don't know, vitamin K is a prescription drug in many countries for treating/preventing osteoporosis, blood pressure, liver disease, neurological disorders, cancer, etc. Japan is where this remarkable substance enjoys perhaps the most prestige as an actual drug for...
A great series of studies performed in the 1960s, with Hans Selye spearheading most of the investigations. It is amazing how much was known about human disease and aging, and how much of that knowledge has been so thoroughly forgotten to the point that doctors nowadays have never even heard of...
In addition to its role in bone, brain, and endocrine health now we can add eyes to the list of tissues/organs that may benefit from vitamin K as well. Unfortunately, most studies are still trying to study vitamin K from the point of view of osteocalcin and carboxylation, which only explains a...
Abstract
The present study describes the hair growth-promoting effects of sodium thiosulfate (STS), a widely used compound, in mice. STS accelerated hair growth in the "telogen model", suggesting that it stimulates telogen hair follicles to reenter the anagen phase of hairgrowth. In the same...
Human equivalent dose was about 12mg daily, duration was just 4 days. Cyproheptadine prevented AND reversed soft tissue calcification by acting as an anti-heparin agent, which is similar to what vitamin K2 does.
http://www.ncbi.nlm.nih.gov/pubmed/14324165
"...In the rat, cyproheptadine...
http://www.ncbi.nlm.nih.gov/pubmed/17138823/
Arterial calcification (AC) is generally regarded as an independent risk factor for cardiovascular morbidity and mortality. Matrix Gla protein (MGP) is a potent inhibitor of AC, and its activity depends on vitamin K (VK). In rats, inactivation of...
I always thought that this would be a very logical explanation, given that both Peat and official medicine are aware of the dangers of soft-tissue calcification. However, I was surprised to find out that officially the cause of age-related macular degeneration is still considered "unknown"...