1. F

    Cholinergics are the only thing that makes my digestion move

    Trying to figure out a good solution for a dilemma I have. On one hand, I don’t like taking nicotine because of the dependence factor and potential for negative hormonal impact On the other, the cholinergic stimulation (I assume) is seemingly the only thing that makes my digestion move. On...
  2. Mauritio

    Coffee/Caffeine might help alzheimers

    "Espresso coffee is among the most consumed beverages in the world. Recent studies report a protective activity of the coffee beverage against neurodegenerative disorders such as Alzheimer′s disease. Alzheimer′s disease belongs to a group of disorders, called tauopathies, which are characterized...
  3. S

    Adhd Drugs That Don't Harm Your Health

    Are there any ADHD medications that aren't so bad for your health? I was diagnosed with adhd and my doctor put me on ritalin. But in the forum I read that Ritalin would be estrogenic and would lower body temperature. I already take caffeine, taurine and thiamine to help me. Any help is appreciated.
  4. Sitaruîm

    Coffee and Cholinesterase (AChE)

    In Ray's article about learned helplessness, arguably his most important article, one of the main points seems to be that low cholinesterase leads to overexcitation of the nerves and to cell death. He cites articles that show that rats living in idyllic environments have high levels of...
  5. TMCMac

    AlloP is helping a lot with anxiety and mood! Can I replicate this without it? Would it be sustainable long term?

    I have struggled with a lot of anxiety and mood lately as I work 70 hours and I got Georgis AlloP and its helped a lot with mood and Ive noticed it increases my wanting to socialize it comes so much more natural. I take 4-8mg allop for the past week. I also pair it with metergoline 4mg. I...
  6. NewACC

    Role of Cholinergic and Dopamine Receptors in the Physiology of Caffeine Tolerance

    Dear Forum Members, I found three interesting studies on reversing (or reducing) caffeine tolerance, by adding to chronic (or sub-chronic) caffeine treatment, either the dopamine agonists bromocriptine (a predominantly d2/d3 family agonist) or pergolide (a very potent d1 agonist), or...
  7. BestSinceDAYONE

    Caffeine relieves my migraines...but why?

    So the last few days I've had huge migraines. I started Levothyroxine (that may be it) and am on a low carb diet so I don't know what it is. I've tried different supplements to help and for some reason a low dose of caffeine 100 mg - 200 mg seems to relieve the headache but coffee by itself DOES...
  8. Green Dot

    Recovering from coffee overdose

    Hi everyone, first of all, Happy New Years. As of typing this, I still feel off, so pardon any errors. So a few days back, I believe I had too much coffee, and as a result, had a panic attack. I haven’t really felt the same since then. I feel much, much duller, I also feel dizzy at times...
  9. Mauritio

    Testosterone, progesterone, caffeine and thymoquinone inhibit Coronavirus through HSP-binding

    So this study shows that one of the heat shock proteins is important for viral entry of coronaviruses (and many other pathogens!). The author looked for substances that are helpful in binding to HSPA5 ,so it won't bind to the virus. That's at least how I'm reading it. It's already known that...
  10. Hans

    Should you quit coffee to fix a vitamin B1 deficiency?

    In my newsletter, I asked which topic people would like to see the most, and coffee and B1 were upvoted the most. I know it was also a "hot" topic a while back on the forum, so that's why I decided to post it here as well. View:
  11. Outdoctrination

    Cool coffee video

    View: This video talks a lot about the key reasons Peat and others in the bioenergetic community think coffee is so valuable. Well done.
  12. B

    £14 shampoo is used to treat hair loss associated with COVID‐19

    Dr Fisherman might want to consider that the DHT theory is bogus. 'They are sulphate free, no dangerous chemicals to harm people's hair and they are very rich in lots of good stuff such as biotin, caffeine, rosemary, niacinamide, argan oil and, more importantly, they possess DHT blocking...
  13. BearWithMe

    Boosting metabolism causes huge stress reaction in very well fed body

    I'm eating 400-500g of sugar and 200-250g of protein every day. Around 3000 kcal daily. All good quality, Peaty foods. Oranges, raisins, milk, cheese, organ meats. I'm eating every hour or so. Yet I can't handle even the slightest metabolic boost. 100mg of caffeine, 50mg of niacinamide, 150mg...
  14. cupofcoffee

    Post-diagnostic coffee and tea consumption and breast cancer survival
  15. cupofcoffee

    Coffee polyphenols ameliorate cognitive decline via maintenance of blood-brain barrier (BBB) integrity in senescence-accelerated mouse prone 8 (SAMP8)
  16. cupofcoffee

    Caffeine promotes the expression of telomerase reverse transcriptase to regulate cellular senescence and aging!divAbstract
  17. Hans

    The only thing fat burners burn is your wallet

    This article is not all about bashing fat burners, but elaborates on the concept of metabolic rate, fat and glucose oxidation and common misconceptions when it comes to fat burners. Let me know your thoughts.
  18. B

    Confused about Caffeine

    Hi everyone, I wanted to post this topic because it has been on my mind obsessively for the past couple weeks. I read Ray peat and Haidut's studies on caffeine and got real excited at the prospect of caffeine because I usually feel better cognitively and less anxiety on average when using...
  19. IROM

    Alpecin shampoo: Caffeine, Taurine and Niacinamide (are corporations on to Peating?)

    Just bough this German brand: Alpecin. It contains caffeine, taurine and niacinamide. After a long search for a perfect ready-made shampoo, I may have found it. I was looking in American stores for the longest time and all the caffeine shampoos have garbage like hemp oil or other seed oils...
  20. M

    Coffee & Constipation

    Am I the only one here for whom coffee sometimes causes constipation? I notice that when I stop drinking it, and switch to tea, my transit time improves dramatically. Does anyone know why this happens? My only guess is that the nervous system activation from the caffeine is somehow having a...