I notice that when I am low serotonin - I don't really have feelings in the sense of romantic relationships - I don't get jealous nor do I care for any of my exes or any girl that I have ever talked to or made a connection with - I feel like talking to girls and having relations with them but I do not feel emotionally attached in any way shape or form
Whenever I have had a crush on a girl - I notice I was not low-serotonin in that state and as soon as I lower serotonin I stop caring about what happens - in a low-serotonergic state - I'm down to have relations but don't feel emotionally attached to any specific girl.
It seems that oxytocin activates serotonin ? What about vice-versa - is being in a medium or high-serotonergic state make one "vulnerable" to forming emotional attachments/Crushes or bonding connections via oxytocin ? My knowledge on the subject is limited so please correct me if I am wrong
"We found that oxytocin provokes the release of serotonin, which in turn impacts on the serotonin 1A receptor system, by modulating its availability. This happens in several key brain regions for social behavior, such as the amygdala and insula."
"Our results show that oxytocin administration in nonhuman primates influences serotoninergic neurotransmission via at least two ways: (1) by provoking a release of serotonin in key limbic regions; and (2) by increasing the availability of 5-HT1AR receptors in the same limbic areas. Because these two molecules are important for social behavior"
Based on these descriptions of how oxytocin structurally influences serotonin - it seems the immediate disruption of oxytocin would have some drawbacks - would going through a break-up have a negative impact on how serotonin is working in the brain which may be the cause of people crying in break-ups or lashing out at their exes ? I'm thinking of experiences of people trying to quit SSRI's acting erratically and it seems to be a similar effect at least by sound
Whenever I have had a crush on a girl - I notice I was not low-serotonin in that state and as soon as I lower serotonin I stop caring about what happens - in a low-serotonergic state - I'm down to have relations but don't feel emotionally attached to any specific girl.
It seems that oxytocin activates serotonin ? What about vice-versa - is being in a medium or high-serotonergic state make one "vulnerable" to forming emotional attachments/Crushes or bonding connections via oxytocin ? My knowledge on the subject is limited so please correct me if I am wrong
Oxytocin and Serotonin Brain Mechanisms in the Nonhuman Primate
Oxytocin (OT) is increasingly studied for its therapeutic potential in psychiatric disorders, which are associated with the deregulation of several neurotransmission systems. Studies in rodents demonstrated that the interaction between OT and serotonin (5-HT) is critical for several aspects of...
www.jneurosci.org
"We found that oxytocin provokes the release of serotonin, which in turn impacts on the serotonin 1A receptor system, by modulating its availability. This happens in several key brain regions for social behavior, such as the amygdala and insula."
"Our results show that oxytocin administration in nonhuman primates influences serotoninergic neurotransmission via at least two ways: (1) by provoking a release of serotonin in key limbic regions; and (2) by increasing the availability of 5-HT1AR receptors in the same limbic areas. Because these two molecules are important for social behavior"
Based on these descriptions of how oxytocin structurally influences serotonin - it seems the immediate disruption of oxytocin would have some drawbacks - would going through a break-up have a negative impact on how serotonin is working in the brain which may be the cause of people crying in break-ups or lashing out at their exes ? I'm thinking of experiences of people trying to quit SSRI's acting erratically and it seems to be a similar effect at least by sound
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