Mauritio
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- Joined
- Feb 26, 2018
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Many people commonly attribute gelatin's anti-inflammatory effects solely to the amino acid glycine, and perhaps also to proline or hydroxyproline. However, it appears that gelatin/collagen contains intriguing peptides with a multitude of unique benefits.
This supports the idea of favoring gelatin consumption over relying solely on glycine. According to Peat, the advantages of gelatin on arthritis may not necessarily arise from its impact on collagen but likely from the anti-inflammatory properties of its amino acids. Considering these studies, it could equally be attributed to the peptides, given their potent anti-inflammatory effects.
In this particular study, it was demonstrated that bovine collagen peptides significantly reduced TLR4, COX2, NO, and various pro-inflammatory cytokines.
Beyond reducing intestinal inflammation, the gelatin peptides also exhibited the ability to enhance components such as occludin, contributing to the rebuilding of the intestinal mucosa. Additionally, they influenced the microbiome by increasing the presence of beneficial bacteria, such as Akkermansia."
- The Anti-Inflammatory Effect of Bovine Bone-Gelatin-Derived Peptides in LPS-Induced RAW264.7 Macrophages Cells and Dextran Sulfate Sodium-Induced C57BL/6 Mice
Here is another study on those peptides:
- Spectrum-Effect Relationships between High-Performance Liquid Chromatography (HPLC) Fingerprints and the Antioxidant and Anti-Inflammatory Activities of Collagen Peptides
This supports the idea of favoring gelatin consumption over relying solely on glycine. According to Peat, the advantages of gelatin on arthritis may not necessarily arise from its impact on collagen but likely from the anti-inflammatory properties of its amino acids. Considering these studies, it could equally be attributed to the peptides, given their potent anti-inflammatory effects.
In this particular study, it was demonstrated that bovine collagen peptides significantly reduced TLR4, COX2, NO, and various pro-inflammatory cytokines.
Beyond reducing intestinal inflammation, the gelatin peptides also exhibited the ability to enhance components such as occludin, contributing to the rebuilding of the intestinal mucosa. Additionally, they influenced the microbiome by increasing the presence of beneficial bacteria, such as Akkermansia."
- The Anti-Inflammatory Effect of Bovine Bone-Gelatin-Derived Peptides in LPS-Induced RAW264.7 Macrophages Cells and Dextran Sulfate Sodium-Induced C57BL/6 Mice
Here is another study on those peptides:
- Spectrum-Effect Relationships between High-Performance Liquid Chromatography (HPLC) Fingerprints and the Antioxidant and Anti-Inflammatory Activities of Collagen Peptides