Glucocorticoids Cause Brain Damage

Discussion in 'Scientific Studies' started by jaguar43, Nov 10, 2015.

  1. jaguar43

    jaguar43 Member

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    For the last few years, studies on the use of glucocorticoids ( prednisone, dexamethasone,ect) resulted in a smaller hippocampus and prefrontal cortex. Causing memory loss, attention loss and lower concentration.

    This study shows that Prednisone can actually reduce brain weight and decrease neurons.



    Here is a study on a boy who was taking glucocorticoids, and results showed that he did worse in school than his twin bother who excelled academically, socially, and physically. When they ran a MRI of his brain it showed about 20 % smaller of the hippocampus and decrease activity of prefrontal cortex than his brother.

     
  2. mujuro

    mujuro Member

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    This is exactly what happens in untreated bipolar and schizoprenia. Especially shrunken hippocampi. After a year unmedicated, the very first thing I noticed, on the very first night of taking medication, was that I was able to dream again.
     
  3. Parsifal

    Parsifal Member

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    Is adrenaline a glutocorticoid? If yes then amphetamines that are supposed to enhance memory will in fact damage it? I guess this is the same with estrogens and acetylcholine...
     
  4. OP
    jaguar43

    jaguar43 Member

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    No, adrenaline is not a Glucocorticoid. Though it may increase glucocorticoids through increasing free fatty acid liberation.
     
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